SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q4FTK9

- GCSP_PSYA2

UniProt

Q4FTK9 - GCSP_PSYA2

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Glycine dehydrogenase (decarboxylating)

Gene
gcvP, Psyc_0796
Organism
Psychrobacter arcticus (strain DSM 17307 / 273-4)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO2 is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein By similarity.UniRule annotation

Catalytic activityi

Glycine + [glycine-cleavage complex H protein]-N(6)-lipoyl-L-lysine = [glycine-cleavage complex H protein]-S-aminomethyl-N(6)-dihydrolipoyl-L-lysine + CO2.UniRule annotation

Cofactori

Pyridoxal phosphate By similarity.UniRule annotation

GO - Molecular functioni

  1. glycine dehydrogenase (decarboxylating) activity Source: UniProtKB-EC
  2. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. glycine decarboxylation via glycine cleavage system Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

Pyridoxal phosphate

Enzyme and pathway databases

BioCyciPARC259536:GI3A-823-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glycine dehydrogenase (decarboxylating) (EC:1.4.4.2)
Alternative name(s):
Glycine cleavage system P-protein
Glycine decarboxylase
Glycine dehydrogenase (aminomethyl-transferring)
Gene namesi
Name:gcvP
Ordered Locus Names:Psyc_0796
OrganismiPsychrobacter arcticus (strain DSM 17307 / 273-4)
Taxonomic identifieri259536 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesMoraxellaceaePsychrobacter
ProteomesiUP000000546: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 965965Glycine dehydrogenase (decarboxylating)UniRule annotationPRO_0000227122Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei711 – 7111N6-(pyridoxal phosphate)lysine By similarity

Interactioni

Subunit structurei

The glycine cleavage system is composed of four proteins: P, T, L and H By similarity.

Protein-protein interaction databases

STRINGi259536.Psyc_0796.

Structurei

3D structure databases

ProteinModelPortaliQ4FTK9.

Family & Domainsi

Sequence similaritiesi

Belongs to the GcvP family.

Phylogenomic databases

eggNOGiCOG1003.
HOGENOMiHOG000239369.
KOiK00281.
OMAiFDSRPYS.
OrthoDBiEOG6HMXDX.

Family and domain databases

Gene3Di3.40.640.10. 2 hits.
HAMAPiMF_00711. GcvP.
InterProiIPR020580. GDC-P_N.
IPR020581. GDC_P.
IPR003437. GDC_P_homo.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11773. PTHR11773. 1 hit.
PfamiPF02347. GDC-P. 2 hits.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 3 hits.
TIGRFAMsiTIGR00461. gcvP. 1 hit.

Sequencei

Sequence statusi: Complete.

Q4FTK9-1 [UniParc]FASTAAdd to Basket

« Hide

MTISQNPTLD TFKGLFNEAE FVYRHLGSND AKQADLLSAI GYKDMATFIN    50
DTVPEPVRLH KELDLPVAMS EHAALAKLRT MADDITVNKS YIGQGYSPVR 100
MPAVIQRNVL ENPGWYTAYT PYQAEIAQGR LEALLNFQQV CIDLTGLELA 150
GASLLDEATA AAEAMAMSKR VSKSKSMQFF VDDRVYSQTL DVINTRAKYF 200
GWEVVVGDFE LAKSGDYFGA LFQYVGVEGD VKDLTDVIAA VKKNKTYVNV 250
VSDIMSLVLL KSPADMGADV ALGSTQRFGI PMGFGGPHAA YFAFSDKAKR 300
SAPGRIIGVS KDSQGNTALR MALQTREQHI RREKANSNIC TSQVLLANLA 350
GMYAVYHGPG GVKRIATRIH AFATAFADVI KNANDSNLNV VHDQFFDSVV 400
IDCGSEKLAT QIFENADNVG YNLWRLGDSK LSVAFSETSD QEDFKILTQL 450
FVTKAHDLPE DARISLDSTH LRTDDILTHP VFNSHHTEHE MLRYLKSLED 500
KDLAMNRSMI SLGSCTMKLN ATSEMLPITW PEFANVHPFA PRDQVTGYVA 550
MIDSLQEQLK AITGFDDVSM QPNSGASGEY AGLLAIRRYH ESLGETDRDV 600
CLIPMSAHGT NPATAMMMGM KVVVVKTDDN GNVDIDDLTA KSEEHSARLG 650
ALMITYPSTH GVFEEGIRKI CDLIHKHGGQ VYMDGANMNA QVGMMQPADV 700
GADVLHMNLH KTFCIPHGGG GPGMGPIGMK SHLAPFMANH TLSPVHNAQK 750
DCSAVSAAPY GSASILPISW MYIAMMGRDG LLKATELALL NANYVAAELK 800
DYYPVLYTGK NGRVAHECII DIRPLKEETG ISESDIAKRL MDYGFHSPTM 850
SFPVAGTLMI EPTESESKEE LDRFISALKS IKAEAMKAKA GEDNWTLENN 900
PLVNAPHTAA MVIDGEWTYP YSRETAAFPL PYIRTNKFWP SVARVDDAYG 950
DKNLMCSCPS IENYM 965
Length:965
Mass (Da):105,914
Last modified:August 30, 2005 - v1
Checksum:i9CC5BCC617624E50
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000082 Genomic DNA. Translation: AAZ18649.1.
RefSeqiYP_264083.1. NC_007204.1.

Genome annotation databases

EnsemblBacteriaiAAZ18649; AAZ18649; Psyc_0796.
GeneIDi3514644.
KEGGipar:Psyc_0796.
PATRICi23056049. VBIPsyArc98534_0945.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000082 Genomic DNA. Translation: AAZ18649.1 .
RefSeqi YP_264083.1. NC_007204.1.

3D structure databases

ProteinModelPortali Q4FTK9.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 259536.Psyc_0796.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAZ18649 ; AAZ18649 ; Psyc_0796 .
GeneIDi 3514644.
KEGGi par:Psyc_0796.
PATRICi 23056049. VBIPsyArc98534_0945.

Phylogenomic databases

eggNOGi COG1003.
HOGENOMi HOG000239369.
KOi K00281.
OMAi FDSRPYS.
OrthoDBi EOG6HMXDX.

Enzyme and pathway databases

BioCyci PARC259536:GI3A-823-MONOMER.

Family and domain databases

Gene3Di 3.40.640.10. 2 hits.
HAMAPi MF_00711. GcvP.
InterProi IPR020580. GDC-P_N.
IPR020581. GDC_P.
IPR003437. GDC_P_homo.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view ]
PANTHERi PTHR11773. PTHR11773. 1 hit.
Pfami PF02347. GDC-P. 2 hits.
[Graphical view ]
SUPFAMi SSF53383. SSF53383. 3 hits.
TIGRFAMsi TIGR00461. gcvP. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "The genome sequence of Psychrobacter arcticus 273-4, a psychroactive Siberian permafrost bacterium, reveals mechanisms for adaptation to low-temperature growth."
    Ayala-del-Rio H.L., Chain P.S., Grzymski J.J., Ponder M.A., Ivanova N., Bergholz P.W., Di Bartolo G., Hauser L., Land M., Bakermans C., Rodrigues D., Klappenbach J., Zarka D., Larimer F., Richardson P., Murray A., Thomashow M., Tiedje J.M.
    Appl. Environ. Microbiol. 76:2304-2312(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 17307 / 273-4.

Entry informationi

Entry nameiGCSP_PSYA2
AccessioniPrimary (citable) accession number: Q4FTK9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 7, 2006
Last sequence update: August 30, 2005
Last modified: May 14, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi