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Q4FQB4 (SYR_PSYA2) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 63. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:Psyc_1946
OrganismPsychrobacter arcticus (strain DSM 17307 / 273-4) [Complete proteome] [HAMAP]
Taxonomic identifier259536 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesMoraxellaceaePsychrobacter

Protein attributes

Sequence length609 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 609609Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_0000242073

Regions

Motif132 – 14211"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
Q4FQB4 [UniParc].

Last modified August 30, 2005. Version 1.
Checksum: 7718E72C758D6137

FASTA60967,269
        10         20         30         40         50         60 
MSQAQINTLA SLFDSAIAVL KNDGELPADW QNNSQITRTK DASHGDFASN IALTAAKAAK 

        70         80         90        100        110        120 
ANPRQVAEKI VNALPENQDI RQIEIAGPGF INVFLNTEAK FAVLDDIFNL QAGFGLSKQF 

       130        140        150        160        170        180 
DGQKVQVEFV SANPTSSLHV GHGRGAAFGM SVSNLLEAIG YDVTREYYVN DAGRQMDILA 

       190        200        210        220        230        240 
TSTYLRYLET NGEPVTFPVN GYQGDYVSDI AQTLKTQHAD TYVHRFAEIA KDVPEDAQFE 

       250        260        270        280        290        300 
INADGEKVLL SGDKEAHIDG LIANSKALLG SGYELFLNAA LSSILADIKD DLNDFGVSYE 

       310        320        330        340        350        360 
CWFSERSIDS EIEPVLQILE DKGYLYEKDG NIWFKSTDFG DEKDRVVRRA NGQSTYFASD 

       370        380        390        400        410        420 
IAYHKNKFDR GFDKVVNVWG ADHHGYVPRV KAALLALGID ADRLDVVLVQ FVALWRGDEK 

       430        440        450        460        470        480 
VQMSSRSGKF VTLRELRHEV GNDAARFYYV ARKPEVHVDF DLELAKSQSK DNLVYYIQYA 

       490        500        510        520        530        540 
HARVCRVLEK LEASGLSVND AMGAEQQELL VASSEEELIK LLAAYPATLL RSATGYEPHI 

       550        560        570        580        590        600 
LTNYLKELAA LFHGWYDSNR ILPVSLTSGE TPSADEMAMM QARLRLSKAV RLVISNGLGL 


LGLSAPSSM 

« Hide

References

[1]"The genome sequence of Psychrobacter arcticus 273-4, a psychroactive Siberian permafrost bacterium, reveals mechanisms for adaptation to low-temperature growth."
Ayala-del-Rio H.L., Chain P.S., Grzymski J.J., Ponder M.A., Ivanova N., Bergholz P.W., Di Bartolo G., Hauser L., Land M., Bakermans C., Rodrigues D., Klappenbach J., Zarka D., Larimer F., Richardson P., Murray A., Thomashow M., Tiedje J.M.
Appl. Environ. Microbiol. 76:2304-2312(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 17307 / 273-4.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000082 Genomic DNA. Translation: AAZ19794.1.
RefSeqYP_265228.1. NC_007204.1.

3D structure databases

ProteinModelPortalQ4FQB4.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING259536.Psyc_1946.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAZ19794; AAZ19794; Psyc_1946.
GeneID3515916.
KEGGpar:Psyc_1946.
PATRIC23058789. VBIPsyArc98534_2299.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247214.
KOK01887.
OMAHARICQV.
OrthoDBEOG6JB13C.

Enzyme and pathway databases

BioCycPARC259536:GI3A-1991-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 2 hits.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
ProtoNetSearch...

Entry information

Entry nameSYR_PSYA2
AccessionPrimary (citable) accession number: Q4FQB4
Entry history
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: August 30, 2005
Last modified: May 14, 2014
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries