ID   GPH_PSYA2               Reviewed;         230 AA.
AC   Q4FPT7;
DT   30-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT   30-AUG-2005, sequence version 1.
DT   16-JUN-2009, entry version 25.
DE   RecName: Full=Phosphoglycolate phosphatase;
DE            Short=PGPase;
DE            Short=PGP;
DE            EC=3.1.3.18;
GN   OrderedLocusNames=Psyc_2124;
OS   Psychrobacter arcticus (strain DSM 17307 / 273-4).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Moraxellaceae; Psychrobacter.
OX   NCBI_TaxID=259536;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   NASA Astrobiology Institute;
RA   Ayala-del-Rio H.L., Chain P., Ponder M.A., Di Bartolo G., Ivanova N.,
RA   Bergholz P.W., Hauser L., Land M., Bakermans C., Rodrigues D.,
RA   Klappenbach J.A., Zarka D., Larimer F., Richardson P., Thomashow M.F.,
RA   Tiedje J.M.;
RT   "Complete sequence of Psychrobacter arcticum 273-4.";
RL   Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Specifically catalyzes the dephosphorylation of 2-
CC       phosphoglycolate. Is involved in the dissimilation of the
CC       intracellular 2-phosphoglycolate formed during the DNA repair of
CC       3'-phosphoglycolate ends, a major class of DNA lesions induced by
CC       oxidative stress (By similarity).
CC   -!- CATALYTIC ACTIVITY: 2-phosphoglycolate + H(2)O = glycolate +
CC       phosphate.
CC   -!- PATHWAY: Organic acid metabolism; glycolic acid biosynthesis;
CC       glycolic acid from 2-phosphoglycolic acid: step 1/1.
CC   -!- SIMILARITY: Belongs to the HAD-like hydrolase superfamily.
CC       CbbY/cbbZ/gph/yieH family.
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DR   EMBL; CP000082; AAZ19971.1; -; Genomic_DNA.
DR   RefSeq; YP_265405.1; -.
DR   GeneID; 3516112; -.
DR   GenomeReviews; CP000082_GR; Psyc_2124.
DR   KEGG; par:Psyc_2124; -.
DR   NMPDR; fig|259536.4.peg.2096; -.
DR   HOGENOM; Q4FPT7; -.
DR   OMA; Q4FPT7; AVCEQFS.
DR   BioCyc; PARC259536:PSYC_2124-MON; -.
DR   GO; GO:0008967; F:phosphoglycolate phosphatase activity; IEA:HAMAP.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:HAMAP.
DR   HAMAP; MF_00495; -; 1.
DR   InterPro; IPR005834; Dehalogen-like_hydro.
DR   InterPro; IPR006439; HAD-SF_hydro_IA_v1.
DR   InterPro; IPR006402; HAD-SF_hydro_IA_v3.
DR   InterPro; IPR005833; Haloacid_DH/epoxide_hydro.
DR   InterPro; IPR006346; PGP_bact.
DR   Pfam; PF00702; Hydrolase; 1.
DR   PRINTS; PR00413; HADHALOGNASE.
DR   TIGRFAMs; TIGR01549; HAD-SF-IA-v1; 1.
DR   TIGRFAMs; TIGR01509; HAD-SF-IA-v3; 1.
DR   TIGRFAMs; TIGR01449; PGP_bact; 1.
PE   3: Inferred from homology;
KW   Carbohydrate metabolism; Complete proteome; Hydrolase.
FT   CHAIN         1    230       Phosphoglycolate phosphatase.
FT                                /FTId=PRO_0000238172.
FT   ACT_SITE      9      9       Nucleophile (By similarity).
SQ   SEQUENCE   230 AA;  25142 MW;  AB48E503E22515B5 CRC64;
     MDKQLLIFDF DGTLIDSVPD LADAVNAMLT TLGKAPYPID TIRNWVGNGS RMLVERALVG
     KIEVSEGELA KETIDHAEQV FFDAYSKMGG SKTVAYPNVD SGLKKLKAAG FKLALVTNKP
     IRFVPKILQF FGWHDIFSEV LGGDSLPTKK PDPAPLLHVC EVLNINPAQA VMIGDSINDI
     LAGQNANMDT LGLSYGYNYG QDIRQLNPTE AFDDFSALVD YLLKAYPANN
//