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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Pelagibacter ubique (strain HTCC1062)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

  1. arginine-tRNA ligase activity Source: UniProtKB-HAMAP
  2. ATP binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. arginyl-tRNA aminoacylation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciCPEL335992:GH3Z-977-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:SAR11_0970
OrganismiPelagibacter ubique (strain HTCC1062)
Taxonomic identifieri335992 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaSAR11 clusterCandidatus Pelagibacter
ProteomesiUP000002528 Componenti: Chromosome

Subcellular locationi

  1. Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 577577Arginine--tRNA ligasePRO_0000242061Add
BLAST

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi335992.SAR11_0970.

Structurei

3D structure databases

ProteinModelPortaliQ4FM10.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi132 – 14211"HIGH" regionAdd
BLAST

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0018.
HOGENOMiHOG000247214.
KOiK01887.
OMAiLDTHLEF.
OrthoDBiEOG6JB13C.

Family and domain databases

Gene3Di1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPiMF_00123. Arg_tRNA_synth.
InterProiIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSiPR01038. TRNASYNTHARG.
SMARTiSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.
PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q4FM10-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNIFDLYLDK IIILIKKLNK DGSLELPESL NGVNVDIPPS NFDCDISTNV
60 70 80 90 100
AMVLSKANKK SPIDIANILI ELIKNEDEKI ESISAAKPGF INIKFKTIYW
110 120 130 140 150
NNFIKSINQN HKDYGVNNKE KKQKYLIEFV SANPTGPLHV GHCRGAILGD
160 170 180 190 200
VISNILIFNK HDVSKEYYVN DYGNQILNFT KSVFFRIREI LFNEKFPIEN
210 220 230 240 250
SDLYPGDYLV GIAKNIIKSN KVLKFDKFEN VSKELTLLSV SESLKLIKNN
260 270 280 290 300
LSNLGIVHDR FTSETDIVLN NEVQKAIDKL KEKKLVYSGK IKAPKGEDDE
310 320 330 340 350
NWVEREQLLF KSTDFGDDKD RALQKSDKSW TYFASDVAYH DNKLNRNYDT
360 370 380 390 400
LINILGADHA GYIKRITSVV EALSGDKKKL ICKVSQLVKL IKDGKPFKMS
410 420 430 440 450
KRKGDYITVE DLIAEVGKDA TRFIMLNRSS DVELDFDFTK VKEKSKDNPL
460 470 480 490 500
YYVQYCYARI SSVFRHVNLN IENDLNIKDY EFAYTGDEIK ILKKIAEWPK
510 520 530 540 550
CIEAASLRLE PHRIPVYLYE LSSEFHSYWN MGKEDQSKRF INEQKKISND
560 570
KLVFLKVISN VIKSGMDIVG VDTPQKM
Length:577
Mass (Da):66,292
Last modified:August 30, 2005 - v1
Checksum:iE5ADC3D72F8EB0C6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000084 Genomic DNA. Translation: AAZ21778.1.
RefSeqiYP_266382.1. NC_007205.1.

Genome annotation databases

EnsemblBacteriaiAAZ21778; AAZ21778; SAR11_0970.
KEGGipub:SAR11_0970.
PATRICi31991421. VBICanPel5618_0961.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000084 Genomic DNA. Translation: AAZ21778.1.
RefSeqiYP_266382.1. NC_007205.1.

3D structure databases

ProteinModelPortaliQ4FM10.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi335992.SAR11_0970.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAZ21778; AAZ21778; SAR11_0970.
KEGGipub:SAR11_0970.
PATRICi31991421. VBICanPel5618_0961.

Phylogenomic databases

eggNOGiCOG0018.
HOGENOMiHOG000247214.
KOiK01887.
OMAiLDTHLEF.
OrthoDBiEOG6JB13C.

Enzyme and pathway databases

BioCyciCPEL335992:GH3Z-977-MONOMER.

Family and domain databases

Gene3Di1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPiMF_00123. Arg_tRNA_synth.
InterProiIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSiPR01038. TRNASYNTHARG.
SMARTiSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.
PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: HTCC1062.

Entry informationi

Entry nameiSYR_PELUB
AccessioniPrimary (citable) accession number: Q4FM10
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: August 30, 2005
Last modified: April 1, 2015
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.