Q4FLZ5 (Q4FLZ5_PELUB) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
DNA gyrase subunit A EMBL AAZ21793.1
EC=5.99.1.3 EMBL AAZ21793.1

Gene names

Name:	gyrA EMBL AAZ21793.1
Ordered Locus Names:	SAR11_0985

Organism

Pelagibacter ubique (strain HTCC1062) [Complete proteome] [HAMAP] EMBL AAZ21793.1

Taxonomic identifier

335992 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › SAR11 cluster › Candidatus Pelagibacter

Protein attributes

Sequence length	849 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	DNA gyrase negatively supercoils closed circular double-stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings By similarity. SAAS SAAS006691
Catalytic activity	ATP-dependent breakage, passage and rejoining of double-stranded DNA. SAAS SAAS006691
Subcellular location	Cytoplasm By similarity SAAS SAAS006691.

Ontologies

Keywords
Cellular component	Cytoplasm SAAS SAAS006691
Ligand	ATP-binding SAAS SAAS006691 DNA-binding SAAS SAAS006691 Nucleotide-binding
Molecular function	Isomerase Topoisomerase SAAS SAAS006691
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA topological change Inferred from electronic annotation. Source: InterPro regulation of transcription, DNA-dependent Inferred from electronic annotation. Source: InterPro
Cellular component	chromosome Inferred from electronic annotation. Source: InterPro cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW DNA topoisomerase (ATP-hydrolyzing) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q4FLZ5 [UniParc]. Last modified August 30, 2005. Version 1. Checksum: DF97CB82701BAF11	FASTA	849	94,583
	10 20 30 40 50 60 MKDTEIPKDK NIKLISMHDE MSSSYLSYAM SVIVSRALPD VRDGLKPVHR RILFAMYKGG 70 80 90 100 110 120 YDWSKQFRKS ARIVGDVIGK YHPHGDQSVY DALVRMVQDF SMSLPLVQGQ GNFGSIDGDP 130 140 150 160 170 180 AAAMRYTETR LAKVSQYLID DIEKDTIEYK SNYDETEKEP SVLPAQYPNL LVNGAGGIAV 190 200 210 220 230 240 GMATSIPPHN LGEIIDGTLA LIENKDIKIK ELMKHIPGPD FPTGGVIIGK EIIKAGYNVG 250 260 270 280 290 300 RGSFKIRGEI SVEAQKNGRE RLVITSVPYQ VNKSVLNERI AQLVREKKIE GIKDIRDESN 310 320 330 340 350 360 REGIRVAIDL RNGVEPETIK RLLYKNTSIE SSFGFNTLAI VDGKPKICNL KEFLTNFLTF 370 380 390 400 410 420 REDVVIKKTK FDLKKAEDRA HILIGLSVSV ENLDKIIKII RSSKTPDDAK KSLLNTKWKI 430 440 450 460 470 480 NKSLKLISLV EDKKEKNLYS LSDPQVIAIL ELRLQKLTAL GINEIEVEIK KLADLIKGYK 490 500 510 520 530 540 KIINSKKELL NVISEELKTI KEKFAVPRRT KIIDAILNYD IEETIQKESV IITVTLQGYI 550 560 570 580 590 600 KRGALSSVKQ QKRGGKGKSG ITTRDEDSVV QTLSVNTHTS VLFFSTEGLV YKIKAWKIPE 610 620 630 640 650 660 GSTTSKGKSL FNILPLKNHQ SISSIMPFPD EESDTKNLQI VFATAKGKVR KNSLEDFSSI 670 680 690 700 710 720 NSAGKIAIKL DPNDKIVGVE ICKDDQDVML STKNGKCIRF ESKKLRIFKG RSSKGIKGIE 730 740 750 760 770 780 LSPNDEIVSL SITNKEKIKK DTKSDGRFVL SITENGYGKK TLNNEYRVTN RGGKGIIGIV 790 800 810 820 830 840 NSPRNGSICS SFPVIEGDDV MISTNKGRVI RVAVKEIRTA GRNTQGVRII KLSGDEKVVS AIKIDDNLE

References

[1]

"Genome streamlining in a cosmopolitan oceanic bacterium." Giovannoni S.J., Tripp H.J., Givan S., Podar M., Vergin K.L., Baptista D., Bibbs L., Eads J., Richardson T.H., Noordewier M., Rappe M.S., Short J.M., Carrington J.C., Mathur E.J. Science 309:1242-1245(2005) [PubMed: 16109880] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: HTCC1062.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000084 Genomic DNA. Translation: AAZ21793.1.
RefSeq	YP_266397.1. NC_007205.1.
3D structure databases
ProteinModelPortal	Q4FLZ5.
SMR	Q4FLZ5. Positions 34-512.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3517352.
GenomeReviews	Gene locus SAR11_0985 in contig CP000084_GR.
KEGG	pub:SAR11_0985.
PATRIC	31991451. VBICanPel5618_0976.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0188.
HOGENOM	HBG635183.
OMA	TSIPPHR.
PhylomeDB	Q4FLZ5.
Family and domain databases
InterPro	IPR005743. GyrA. IPR006691. GyrA/parC_pinwhl. IPR002205. Topo_IIA_A/C. IPR013758. Topo_IIA_A/C_ab. IPR013757. Topo_IIA_A_a. IPR013760. Topo_IIA_cen. [Graphical view]
Gene3D	G3DSA:3.90.199.10. Topo_IIA_A/C_ab. 1 hit. G3DSA:1.10.268.10. Topo_IIA_A_a. 1 hit.
KO	K02469.
Pfam	PF03989. DNA_gyraseA_C. 6 hits. PF00521. DNA_topoisoIV. 1 hit. [Graphical view]
SMART	SM00434. TOP4c. 1 hit. [Graphical view]
SUPFAM	SSF56719. Topo_IIA_cen. 1 hit.
TIGRFAMs	TIGR01063. GyrA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q4FLZ5_PELUB

Accession

Primary (citable) accession number: Q4FLZ5

Entry history

Integrated into UniProtKB/TrEMBL:	August 30, 2005
Last sequence update:	August 30, 2005
Last modified:	January 25, 2012
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)