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Q4FK88

- Q4FK88_MOUSE

UniProt

Q4FK88 - Q4FK88_MOUSE

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Protein

Annexin

Gene

Anxa1

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. calcium-dependent phospholipid binding Source: UniProtKB-KW
  2. calcium ion binding Source: InterPro
  3. phospholipase inhibitor activity Source: InterPro

GO - Biological processi

  1. arachidonic acid secretion Source: MGI
  2. positive regulation of G1/S transition of mitotic cell cycle Source: MGI
  3. regulation of cell proliferation Source: MGI
  4. signal transduction Source: MGI
Complete GO annotation...

Keywords - Ligandi

Calcium, Calcium/phospholipid-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
AnnexinUniRule annotation
Gene namesi
Name:Anxa1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:96819. Anxa1.

Subcellular locationi

GO - Cellular componenti

  1. sarcolemma Source: MGI
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiQ4FK88.

Expressioni

Gene expression databases

GenevestigatoriQ4FK88.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000097180.

Structurei

3D structure databases

ProteinModelPortaliQ4FK88.
SMRiQ4FK88. Positions 2-344.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domaini

A pair of annexin repeats may form one binding site for calcium and phospholipid.UniRule annotation

Sequence similaritiesi

Belongs to the annexin family.UniRule annotation
Contains 4 annexin repeats.UniRule annotation
Contains annexin repeats.SAAS annotation

Keywords - Domaini

AnnexinUniRule annotationSAAS annotation, RepeatUniRule annotationSAAS annotation

Phylogenomic databases

HOVERGENiHBG061815.

Family and domain databases

Gene3Di1.10.220.10. 4 hits.
InterProiIPR001464. Annexin.
IPR018502. Annexin_repeat.
IPR018252. Annexin_repeat_CS.
IPR002388. AnnexinI.
[Graphical view]
PfamiPF00191. Annexin. 4 hits.
[Graphical view]
PRINTSiPR00196. ANNEXIN.
PR00197. ANNEXINI.
SMARTiSM00335. ANX. 4 hits.
[Graphical view]
PROSITEiPS00223. ANNEXIN. 4 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q4FK88 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAMVSEFLKQ ARFLENQEQE YVQAVKSYKG GPGSAVSPYP SFNVSSDVAA
60 70 80 90 100
LHKAIMVKGV DEATIIDILT KRTNAQRQQI KAAYLKENGK PLDEVLRKAL
110 120 130 140 150
TGHLEEVVLA MLKTPAQFDA DELRGAMKGL GTDEDTLIEI LTTRSNEQIR
160 170 180 190 200
EINRVYREEL KRDLAKDITS DTSGDFRKAL LALAKGDRCQ DLSVNQDLAD
210 220 230 240 250
TDARALYEAG ERRKGTDVNV FTTILTSRSF PHLRRVFQNY GKYSQHDMNK
260 270 280 290 300
ALDLELKGDI EKCLTTIVKC ATSTPAFFAE KLYEAMKGAG TRHKALIRIM
310 320 330 340
VSRSEIDMNE IKVFYQKKYG ISLCQAILDE TKGDYEKILV ALCGGN
Length:346
Mass (Da):38,734
Last modified:August 30, 2005 - v1
Checksum:i9FBBC11B21237D3C
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CT009771 mRNA. Translation: CAJ18120.1.
UniGeneiMm.248360.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CT009771 mRNA. Translation: CAJ18120.1 .
UniGenei Mm.248360.

3D structure databases

ProteinModelPortali Q4FK88.
SMRi Q4FK88. Positions 2-344.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 10090.ENSMUSP00000097180.

Proteomic databases

PRIDEi Q4FK88.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

MGIi MGI:96819. Anxa1.

Phylogenomic databases

HOVERGENi HBG061815.

Miscellaneous databases

ChiTaRSi ANXA1. mouse.
SOURCEi Search...

Gene expression databases

Genevestigatori Q4FK88.

Family and domain databases

Gene3Di 1.10.220.10. 4 hits.
InterProi IPR001464. Annexin.
IPR018502. Annexin_repeat.
IPR018252. Annexin_repeat_CS.
IPR002388. AnnexinI.
[Graphical view ]
Pfami PF00191. Annexin. 4 hits.
[Graphical view ]
PRINTSi PR00196. ANNEXIN.
PR00197. ANNEXINI.
SMARTi SM00335. ANX. 4 hits.
[Graphical view ]
PROSITEi PS00223. ANNEXIN. 4 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Cloning of mouse full open reading frames in Gateway(TM) system entry vector (pDONR201)."
    Ebert L., Muenstermann E., Schatten R., Henze S., Bohn E., Mollenhauer J., Wiemann S., Schick M., Korn B.
    Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ4FK88_MOUSE
AccessioniPrimary (citable) accession number: Q4FK88
Entry historyi
Integrated into UniProtKB/TrEMBL: August 30, 2005
Last sequence update: August 30, 2005
Last modified: October 29, 2014
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)