Nras

Functionⁱ

GO - Molecular functionⁱ

GTPase activity Source: InterPro
GTP binding Source: UniProtKB-KW

Complete GO annotation...

GO - Biological processⁱ

signal transduction Source: InterPro

Complete GO annotation...

Keywordsⁱ

Ligand	GTP-bindingSAAS annotation, Nucleotide-binding

Ligand

GTP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: Nras proteinImported
Gene namesⁱ	Name:NrasImported
Organismⁱ	Mus musculus (Mouse)Imported
Taxonomic identifierⁱ	10090 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus

Organism-specific databases

MGIⁱ	MGI:97376. Nras.

Subcellular locationⁱ

GO - Cellular componentⁱ

membrane Source: InterPro

Complete GO annotation...

PTM / Processingⁱ

Proteomic databases

PaxDbⁱ	Q4FJP3.
PRIDEⁱ	Q4FJP3.

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSMUSG00000027852.
Genevisibleⁱ	Q4FJP3. MM.

Interactionⁱ

Protein-protein interaction databases

IntActⁱ	Q4FJP3. 1 interactor.

IntActⁱ

Q4FJP3. 1 interactor.

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q4FJP3.
SMRⁱ	Q4FJP3.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Phylogenomic databases

eggNOGⁱ	KOG0395. Eukaryota. COG1100. LUCA.
HOGENOMⁱ	HOG000233973.
HOVERGENⁱ	HBG009351.
KEGG Orthology (KO) More...KOⁱ	K07828.

Family and domain databases

InterProⁱ	View protein in InterPro IPR027417. P-loop_NTPase. IPR005225. Small_GTP-bd_dom. IPR001806. Small_GTPase. IPR020849. Small_GTPase_Ras.
PANTHERⁱ	PTHR24070. PTHR24070. 1 hit.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00071. Ras. 1 hit.
SUPFAMⁱ	SSF52540. SSF52540. 1 hit.
TIGRFAMsⁱ	TIGR00231. small_GTP. 1 hit.
PROSITEⁱ	View protein in PROSITE PS51421. RAS. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Complete.

Q4FJP3-1 [UniParc]FASTA Add to basket

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        10         20         30         40         50
MTEYKLVVVG AGGVGKSALT IQLIQNHFVD EYDPTIEDSY RKQVVIDGET 
        60         70         80         90        100
CLLDILDTAG QEEYSAMRDQ YMRTGEGFLC VFAINNSKSF ADINLYREQI 
       110        120        130        140        150
KRVKDSDDVP MVLVGNKCDL PTRTVDTKQA HELAKSYGIP FIETSAKTRQ 
       160        170        180        190 
GVEDAFYTLV REIRQYRMKK LNSSDDGTQG CMGLPCVLMC KTL

Length:193

Mass (Da):21,689

Last modified:August 30, 2005 - v1

Checksum:ⁱBEF9E0AEA88D33F6

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	CT010359 mRNA. Translation: CAJ18567.1.
NCBI Reference Sequences More...RefSeqⁱ	NP_035067.2. NM_010937.2.
UniGeneⁱ	Mm.400954.

Genome annotation databases

GeneIDⁱ	18176.
KEGGⁱ	mmu:18176.

Similar proteinsⁱ

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:

100%	UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%	UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%	UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	CT010359 mRNA. Translation: CAJ18567.1.
NCBI Reference Sequences More...RefSeqⁱ	NP_035067.2. NM_010937.2.
UniGeneⁱ	Mm.400954.

3D structure databases

ProteinModelPortalⁱ	Q4FJP3.
SMRⁱ	Q4FJP3.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

IntActⁱ	Q4FJP3. 1 interactor.

IntActⁱ

Q4FJP3. 1 interactor.

Proteomic databases

PaxDbⁱ	Q4FJP3.
PRIDEⁱ	Q4FJP3.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

GeneIDⁱ	18176.
KEGGⁱ	mmu:18176.

Organism-specific databases

CTDⁱ	4893.
MGIⁱ	MGI:97376. Nras.

Phylogenomic databases

eggNOGⁱ	KOG0395. Eukaryota. COG1100. LUCA.
HOGENOMⁱ	HOG000233973.
HOVERGENⁱ	HBG009351.
KEGG Orthology (KO) More...KOⁱ	K07828.

Miscellaneous databases

ChiTaRSⁱ	Nras. mouse.
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSMUSG00000027852.
Genevisibleⁱ	Q4FJP3. MM.

Family and domain databases

InterProⁱ	View protein in InterPro IPR027417. P-loop_NTPase. IPR005225. Small_GTP-bd_dom. IPR001806. Small_GTPase. IPR020849. Small_GTPase_Ras.
PANTHERⁱ	PTHR24070. PTHR24070. 1 hit.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00071. Ras. 1 hit.
SUPFAMⁱ	SSF52540. SSF52540. 1 hit.
TIGRFAMsⁱ	TIGR00231. small_GTP. 1 hit.
PROSITEⁱ	View protein in PROSITE PS51421. RAS. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	Q4FJP3_MOUSE
Accessionⁱ	Q4FJP3Primary (citable) accession number: Q4FJP3
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	August 30, 2005
	Last sequence update:	August 30, 2005
	Last modified:	July 5, 2017
	This is version 93 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

UniProtKB

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UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q4FJP3 (Q4FJP3_MOUSE)

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Nras protein

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ