SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q4FJK3

- Q4FJK3_MOUSE

UniProt

Q4FJK3 - Q4FJK3_MOUSE

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Submitted name:

Sirt3 protein

Gene
Sirt3, mCG_22591
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 3 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. NAD+ binding Source: InterPro
  2. NAD-dependent histone deacetylase activity (H3-K14 specific) Source: MGI
  3. zinc ion binding Source: Ensembl

GO - Biological processi

  1. aerobic respiration Source: Ensembl
  2. histone H3 deacetylation Source: GOC
  3. peptidyl-lysine deacetylation Source: Ensembl
  4. protein deacetylation Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Sirt3 proteinImported
Submitted name:
Sirtuin 3 (Silent mating type information regulation 2, homolog) 3 (S. cerevisiae), isoform CRA_aImported
Gene namesi
Name:Sirt3Imported
ORF Names:mCG_22591Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1927665. Sirt3.

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: MGI
  2. membrane Source: MGI
  3. mitochondrion Source: MGI
Complete GO annotation...

Expressioni

Gene expression databases

GenevestigatoriQ4FJK3.

Family & Domainsi

Phylogenomic databases

HOVERGENiHBG057095.
InParanoidiQ4FJK3.
KOiK11413.
OMAiVGPFAWQ.

Family and domain databases

Gene3Di3.30.1600.10. 2 hits.
3.40.50.1220. 3 hits.
InterProiIPR029035. DHS-like_NAD/FAD-binding_dom.
IPR003000. Sirtuin.
IPR026591. Sirtuin_cat_small_dom.
IPR017328. Sirtuin_class_I.
IPR026590. Ssirtuin_cat_dom.
[Graphical view]
PANTHERiPTHR11085. PTHR11085. 1 hit.
PfamiPF02146. SIR2. 1 hit.
[Graphical view]
PIRSFiPIRSF037938. SIR2_euk. 1 hit.
SUPFAMiSSF52467. SSF52467. 1 hit.
PROSITEiPS50305. SIRTUIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q4FJK3-1 [UniParc]FASTAAdd to Basket

« Hide

MVGAGISTPS GIPDFRSPGS GLYSNLQQYD IPYPEAIFEL GFFFHNPKPF    50
FMLAKELYPG HYRPNVTHYF LRLLHDKELL LRLYTQNIDG LERASGIPAS 100
KLVEAHGTFV TATCTVCRRS FPGEDIWADV MADRVPRCPV CTGVVKPDIV 150
FFGEQLPARF LLHMADFALA DLLLILGTSL EVEPFASLSE AVQKSVPRLL 200
INRDLVGPFV LSPRRKDVVQ LGDVVHGVER LVDLLGWTQE LLDLMQRERG 250
KLDGQDR 257
Length:257
Mass (Da):28,822
Last modified:August 30, 2005 - v1
Checksum:iF756041FBC9B985E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CT010402 mRNA. Translation: CAJ18608.1.
CH466531 Genomic DNA. Translation: EDL17961.1.
CH466531 Genomic DNA. Translation: EDL17963.1.
RefSeqiNP_001120823.1. NM_001127351.1.
NP_071878.2. NM_022433.2.
UniGeneiMm.244216.

Genome annotation databases

GeneIDi64384.
KEGGimmu:64384.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CT010402 mRNA. Translation: CAJ18608.1 .
CH466531 Genomic DNA. Translation: EDL17961.1 .
CH466531 Genomic DNA. Translation: EDL17963.1 .
RefSeqi NP_001120823.1. NM_001127351.1.
NP_071878.2. NM_022433.2.
UniGenei Mm.244216.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 64384.
KEGGi mmu:64384.

Organism-specific databases

CTDi 23410.
MGIi MGI:1927665. Sirt3.

Phylogenomic databases

HOVERGENi HBG057095.
InParanoidi Q4FJK3.
KOi K11413.
OMAi VGPFAWQ.

Miscellaneous databases

ChiTaRSi SIRT3. mouse.
NextBioi 320063.
SOURCEi Search...

Gene expression databases

Genevestigatori Q4FJK3.

Family and domain databases

Gene3Di 3.30.1600.10. 2 hits.
3.40.50.1220. 3 hits.
InterProi IPR029035. DHS-like_NAD/FAD-binding_dom.
IPR003000. Sirtuin.
IPR026591. Sirtuin_cat_small_dom.
IPR017328. Sirtuin_class_I.
IPR026590. Ssirtuin_cat_dom.
[Graphical view ]
PANTHERi PTHR11085. PTHR11085. 1 hit.
Pfami PF02146. SIR2. 1 hit.
[Graphical view ]
PIRSFi PIRSF037938. SIR2_euk. 1 hit.
SUPFAMi SSF52467. SSF52467. 1 hit.
PROSITEi PS50305. SIRTUIN. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome."
    Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W.
    , Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D.
    Science 296:1661-1671(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MixedImported.
  2. "Cloning of mouse full open reading frames in Gateway(R) system entry vector (pDONR201)."
    Ebert L., Muenstermann E., Schatten R., Henze S., Bohn E., Mollenhauer J., Wiemann S., Schick M., Korn B.
    Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  3. Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
    Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MixedImported.

Entry informationi

Entry nameiQ4FJK3_MOUSE
AccessioniPrimary (citable) accession number: Q4FJK3
Entry historyi
Integrated into UniProtKB/TrEMBL: August 30, 2005
Last sequence update: August 30, 2005
Last modified: June 11, 2014
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi