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Protein
Submitted name:

DNA ligase, putative

Gene

Tc00.1047053506287.200

Organism
Trypanosoma cruzi (strain CL Brener)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. ATP binding Source: InterPro
  2. DNA ligase (ATP) activity Source: UniProtKB-EC

GO - Biological processi

  1. DNA ligation involved in DNA repair Source: InterPro
  2. DNA recombination Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LigaseImported

Names & Taxonomyi

Protein namesi
Submitted name:
DNA ligase, putativeImported (EC:6.5.1.1Imported)
Gene namesi
ORF Names:Tc00.1047053506287.200Imported
OrganismiTrypanosoma cruzi (strain CL Brener)Imported
Taxonomic identifieri353153 [NCBI]
Taxonomic lineageiEukaryotaEuglenozoaKinetoplastidaTrypanosomatidaeTrypanosomaSchizotrypanum
ProteomesiUP000002296 Componenti: Unassembled WGS sequence

Structurei

3D structure databases

ProteinModelPortaliQ4DIW6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

KOiK10747.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
InterProiIPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR029319. DNA_ligase_OB.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF01068. DNA_ligase_A_M. 1 hit.
PF14743. DNA_ligase_OB_2. 1 hit.
[Graphical view]
SUPFAMiSSF50249. SSF50249. 1 hit.
PROSITEiPS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q4DIW6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVLARIGART EMWRRCSCLG RAIVQSVDPS LLFGAGRPRT KQQAEKYKEL
60 70 80 90 100
KNTTIQAAFP HLAACWVGPC WGTVMITPHH ISPLCLKIAV WRCSECLQEF
110 120 130 140 150
EMSIAKFVDQ HGVCPLCKKP QRSLEAPNKE PETTNGSSTE GKNGDFNLGS
160 170 180 190 200
AAAMKMTTTT KNEVVYAKAP RMIHTNYKSV LHDNPEWEEI NIQPMLAQKW
210 220 230 240 250
ETVAAELLNP GPGEEKELLL ASPKIDGVRC LIGYNRRKKE PQFFSRSGIL
260 270 280 290 300
LECCHGLVPH VMPLFEADPT LVLDGELFAP QCNFEELNGL VRRLEKFTTP
310 320 330 340 350
EMRERQAQLL EYFSFDIMHS SQLSSSSAPF SERYRLLKKM VPTCGAKRIS
360 370 380 390 400
AYQHDEEKRK IIRQKQRPDN AAAEGTIKLY HVPAAQVGAE EMDEVLEEAC
410 420 430 440 450
SQGFEGVMIR RPGFPYEHGK RSFGLLKYKT MHDAEYRIVD FLPGQGKFRG
460 470 480 490 500
GLGAFICETK TGIRFNATPK TTYENRLALW GKRQELLGKY LTVQYQELSS
510 520
QDVPRFPVAK AVRGTSEEEF L
Length:521
Mass (Da):58,898
Last modified:September 13, 2005 - v1
Checksum:i67C4D46BA24757B4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAHK01000431 Genomic DNA. Translation: EAN92478.1.
RefSeqiXP_814329.1. XM_809236.1.

Genome annotation databases

GeneIDi3545849.
KEGGitcr:506287.200.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAHK01000431 Genomic DNA. Translation: EAN92478.1.
RefSeqiXP_814329.1. XM_809236.1.

3D structure databases

ProteinModelPortaliQ4DIW6.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi3545849.
KEGGitcr:506287.200.

Phylogenomic databases

KOiK10747.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
InterProiIPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR029319. DNA_ligase_OB.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF01068. DNA_ligase_A_M. 1 hit.
PF14743. DNA_ligase_OB_2. 1 hit.
[Graphical view]
SUPFAMiSSF50249. SSF50249. 1 hit.
PROSITEiPS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas disease."
    El-Sayed N.M., Myler P.J., Bartholomeu D.C., Nilsson D., Aggarwal G., Tran A.N., Ghedin E., Worthey E.A., Delcher A.L., Blandin G., Westenberger S.J., Caler E., Cerqueira G.C., Branche C., Haas B., Anupama A., Arner E., Aslund L.
    , Attipoe P., Bontempi E., Bringaud F., Burton P., Cadag E., Campbell D.A., Carrington M., Crabtree J., Darban H., da Silveira J.F., de Jong P., Edwards K., Englund P.T., Fazelina G., Feldblyum T., Ferella M., Frasch A.C., Gull K., Horn D., Hou L., Huang Y., Kindlund E., Klingbeil M., Kluge S., Koo H., Lacerda D., Levin M.J., Lorenzi H., Louie T., Machado C.R., McCulloch R., McKenna A., Mizuno Y., Mottram J.C., Nelson S., Ochaya S., Osoegawa K., Pai G., Parsons M., Pentony M., Pettersson U., Pop M., Ramirez J.L., Rinta J., Robertson L., Salzberg S.L., Sanchez D.O., Seyler A., Sharma R., Shetty J., Simpson A.J., Sisk E., Tammi M.T., Tarleton R., Teixeira S., Van Aken S., Vogt C., Ward P.N., Wickstead B., Wortman J., White O., Fraser C.M., Stuart K.D., Andersson B.
    Science 309:409-415(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CL BrenerImported.

Entry informationi

Entry nameiQ4DIW6_TRYCC
AccessioniPrimary (citable) accession number: Q4DIW6
Entry historyi
Integrated into UniProtKB/TrEMBL: September 13, 2005
Last sequence update: September 13, 2005
Last modified: March 4, 2015
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.