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Q4CVY8

- Q4CVY8_TRYCC

UniProt

Q4CVY8 - Q4CVY8_TRYCC

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Protein
Submitted name:

Thymidine kinase, putative

Gene

Tc00.1047053511133.20

Organism
Trypanosoma cruzi (strain CL Brener)
Status
Unreviewed - Annotation score: 1 out of 5- Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. ATP binding Source: InterPro
  2. thymidine kinase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

KinaseImported, Transferase

Names & Taxonomyi

Protein namesi
Submitted name:
Thymidine kinase, putativeImported (EC:2.7.1.21Imported)
Gene namesi
ORF Names:Tc00.1047053511133.20Imported
OrganismiTrypanosoma cruzi (strain CL Brener)Imported
Taxonomic identifieri353153 [NCBI]
Taxonomic lineageiEukaryotaEuglenozoaKinetoplastidaTrypanosomatidaeTrypanosomaSchizotrypanum
ProteomesiUP000002296: Unassembled WGS sequence

Structurei

3D structure databases

ProteinModelPortaliQ4CVY8.
SMRiQ4CVY8. Positions 153-328.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the thymidine kinase family.UniRule annotation

Phylogenomic databases

KOiK00857.

Family and domain databases

InterProiIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020633. Thymidine_kinase_CS.
[Graphical view]
PANTHERiPTHR11441. PTHR11441. 1 hit.
PfamiPF00265. TK. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00603. TK_CELLULAR_TYPE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q4CVY8-1 [UniParc]FASTAAdd to Basket

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        10         20         30         40         50
MCTLPSVGVC VCVCVRITFC SSRLGEEGKG REECLASSIA KVGCIVRVNY
60 70 80 90 100
VLHLKKNEFY TPFLYLFVWV VDCTPTHRFT LLYLIFAFPP FFFFFIFFFF
110 120 130 140 150
FVMFASHTST CTLKVHYAED QRNFRLAFGF CASSIQQLLA DTSLQMMLEN
160 170 180 190 200
ESHGHIELII GPMFAGKTTE LMRRVRRELF ARRSCYVIKH SRDARYSRES
210 220 230 240 250
VSSHDKLLLG ATAAVAELRE VGDAWCPYDV VAVDEGQFFP DIVAFCNTAA
260 270 280 290 300
DAGKTVIVSA LDGDYRRQPF DGICRLIPLA ESVKKLTAVC MECHCRSASF
310 320 330 340 350
TYRTVSSEKR ELIGGADMYI AACRTCFVTK SKKRAELEAK GSVQTPDKCS
360 370 380 390 400
DTPAAEKQKG EQREAEEDPI TPPTTIAAAE PPLSASAVRK RPVGVDGNVP
410
TDAERCTSKA RLECH
Length:415
Mass (Da):46,347
Last modified:September 13, 2005 - v1
Checksum:i0A6BD57D96723D13
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAHK01001694 Genomic DNA. Translation: EAN84440.1.
RefSeqiXP_806291.1. XM_801198.1.

Genome annotation databases

GeneIDi3536254.
KEGGitcr:511133.20.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAHK01001694 Genomic DNA. Translation: EAN84440.1 .
RefSeqi XP_806291.1. XM_801198.1.

3D structure databases

ProteinModelPortali Q4CVY8.
SMRi Q4CVY8. Positions 153-328.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 3536254.
KEGGi tcr:511133.20.

Phylogenomic databases

KOi K00857.

Family and domain databases

InterProi IPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020633. Thymidine_kinase_CS.
[Graphical view ]
PANTHERi PTHR11441. PTHR11441. 1 hit.
Pfami PF00265. TK. 1 hit.
[Graphical view ]
SUPFAMi SSF52540. SSF52540. 1 hit.
PROSITEi PS00603. TK_CELLULAR_TYPE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas disease."
    El-Sayed N.M., Myler P.J., Bartholomeu D.C., Nilsson D., Aggarwal G., Tran A.N., Ghedin E., Worthey E.A., Delcher A.L., Blandin G., Westenberger S.J., Caler E., Cerqueira G.C., Branche C., Haas B., Anupama A., Arner E., Aslund L.
    , Attipoe P., Bontempi E., Bringaud F., Burton P., Cadag E., Campbell D.A., Carrington M., Crabtree J., Darban H., da Silveira J.F., de Jong P., Edwards K., Englund P.T., Fazelina G., Feldblyum T., Ferella M., Frasch A.C., Gull K., Horn D., Hou L., Huang Y., Kindlund E., Klingbeil M., Kluge S., Koo H., Lacerda D., Levin M.J., Lorenzi H., Louie T., Machado C.R., McCulloch R., McKenna A., Mizuno Y., Mottram J.C., Nelson S., Ochaya S., Osoegawa K., Pai G., Parsons M., Pentony M., Pettersson U., Pop M., Ramirez J.L., Rinta J., Robertson L., Salzberg S.L., Sanchez D.O., Seyler A., Sharma R., Shetty J., Simpson A.J., Sisk E., Tammi M.T., Tarleton R., Teixeira S., Van Aken S., Vogt C., Ward P.N., Wickstead B., Wortman J., White O., Fraser C.M., Stuart K.D., Andersson B.
    Science 309:409-415(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CL BrenerImported.

Entry informationi

Entry nameiQ4CVY8_TRYCC
AccessioniPrimary (citable) accession number: Q4CVY8
Entry historyi
Integrated into UniProtKB/TrEMBL: September 13, 2005
Last sequence update: September 13, 2005
Last modified: October 29, 2014
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3