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Protein

Glycosyltransferase-like domain-containing protein 1

Gene

GTDC1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Protein family/group databases

CAZyiGT4. Glycosyltransferase Family 4.

Names & Taxonomyi

Protein namesi
Recommended name:
Glycosyltransferase-like domain-containing protein 1
Alternative name(s):
Mannosyltransferase-like protein Xa1 Publication
Mat-Xa1 Publication
Gene namesi
Name:GTDC1
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

HGNCiHGNC:20887. GTDC1.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134892601.

Polymorphism and mutation databases

BioMutaiGTDC1.
DMDMi121946960.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 458458Glycosyltransferase-like domain-containing protein 1PRO_0000311088Add
BLAST

Proteomic databases

MaxQBiQ4AE62.
PaxDbiQ4AE62.
PRIDEiQ4AE62.

PTM databases

iPTMnetiQ4AE62.
PhosphoSiteiQ4AE62.

Expressioni

Tissue specificityi

Ubiquitous. Expressed at high levels in the lung, brain, spleen, testis, placenta. ovary, pancreas, spleen and peripheral blood leukocytes. Expressed at low level in the colon, small intestine, kidney, skeletal muscle and thymus. Expressed at high level in colon adenocarcinoma.2 Publications

Gene expression databases

BgeeiQ4AE62.
CleanExiHS_GTDC1.
ExpressionAtlasiQ4AE62. baseline and differential.
GenevisibleiQ4AE62. HS.

Organism-specific databases

HPAiHPA036694.

Interactioni

Protein-protein interaction databases

BioGridi122829. 1 interaction.

Structurei

3D structure databases

ProteinModelPortaliQ4AE62.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG410IICG. Eukaryota.
ENOG410ZWWX. LUCA.
GeneTreeiENSGT00390000006631.
HOVERGENiHBG106976.
InParanoidiQ4AE62.
OMAiFMPKHKT.
OrthoDBiEOG7N63MQ.
PhylomeDBiQ4AE62.
TreeFamiTF324818.

Family and domain databases

InterProiIPR001296. Glyco_trans_1.
IPR022701. GlycosylTrfase_1_N.
[Graphical view]
PfamiPF12038. DUF3524. 1 hit.
PF00534. Glycos_transf_1. 1 hit.
[Graphical view]

Sequences (6)i

Sequence statusi: Complete.

This entry describes 6 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: Q4AE62-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MSILIIEAFY GGSHKQLVDL LQEELGDCVV YTLPAKKWHW RARTSALYFS
60 70 80 90 100
QTIPISEHYR TLFASSVLNL TELAALRPDL GKLKKILYFH ENQLIYPVKK
110 120 130 140 150
CQERDFQYGY NQILSCLVAD VVVFNSVFNM ESFLTSMGKF MKLIPDHRPK
160 170 180 190 200
DLESIIRPKC QVIYFPIRFP DVSRFMPKHK TTHLKKMLGL KGNGGAVLSM
210 220 230 240 250
ALPFQPEQRD SEDLLKNFNS ECDTHCGLDT ARQEYLGNSL RQESDLKKST
260 270 280 290 300
SSDNSSSHHG ENKQNLTVDP CDILGGVDNQ QRLLHIVWPH RWEHDKDPES
310 320 330 340 350
FFKVLMHLKD LGLNFHVSVL GETFTDVPDI FSEAKKALGS SVLHWGYLPS
360 370 380 390 400
KDDYFQVLCM ADVVISTAKH EFFGVAMLEA VYCGCYPLCP KDLVYPEIFP
410 420 430 440 450
AEYLYSTPEQ LSKRLQNFCK RPDIIRKHLY KGEIAPFSWA ALHGKFRSLL

TTEPREDL
Length:458
Mass (Da):52,597
Last modified:September 13, 2005 - v1
Checksum:iC1B4BCD52B354A72
GO
Isoform 2 (identifier: Q4AE62-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     293-377: Missing.

Show »
Length:373
Mass (Da):43,037
Checksum:i4C74F018A45D7D9D
GO
Isoform 3 (identifier: Q4AE62-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     293-458: Missing.

Show »
Length:292
Mass (Da):33,576
Checksum:i9C0E3C895DF5528C
GO
Isoform 4 (identifier: Q4AE62-4) [UniParc]FASTAAdd to basket

Also known as: c

The sequence of this isoform differs from the canonical sequence as follows:
     329-376: DIFSEAKKAL...TAKHEFFGVA → GWKLCTVGVT...SRISARDQIL
     377-458: Missing.

Note: No experimental confirmation available.
Show »
Length:376
Mass (Da):43,316
Checksum:iC5EA3CF062C9E077
GO
Isoform 5 (identifier: Q4AE62-5) [UniParc]FASTAAdd to basket

Also known as: f

The sequence of this isoform differs from the canonical sequence as follows:
     1-59: MSILIIEAFY...SQTIPISEHY → MLTLHVWIWFGFMPCPNLMQNYNHQCC

Note: No experimental confirmation available.
Show »
Length:426
Mass (Da):49,070
Checksum:i3D4A7CECA16FB9F1
GO
Isoform 6 (identifier: Q4AE62-6) [UniParc]FASTAAdd to basket

Also known as: d

The sequence of this isoform differs from the canonical sequence as follows:
     1-129: Missing.

Note: No experimental confirmation available.
Show »
Length:329
Mass (Da):37,681
Checksum:iCF4CE22B171213F9
GO

Sequence cautioni

The sequence AAX93131.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated
The sequence BAB13904.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti137 – 1371M → I.2 Publications
Corresponds to variant rs3731958 [ dbSNP | Ensembl ].
VAR_037136

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1 – 129129Missing in isoform 6. VSP_057596Add
BLAST
Alternative sequencei1 – 5959MSILI…ISEHY → MLTLHVWIWFGFMPCPNLMQ NYNHQCC in isoform 5. VSP_057597Add
BLAST
Alternative sequencei293 – 458166Missing in isoform 3. 1 PublicationVSP_029378Add
BLAST
Alternative sequencei293 – 37785Missing in isoform 2. 1 PublicationVSP_029379Add
BLAST
Alternative sequencei329 – 37648DIFSE…FFGVA → GWKLCTVGVTHFVLKIWFIP KYFQLNICILHLNSFQKGSR ISARDQIL in isoform 4. VSP_057598Add
BLAST
Alternative sequencei377 – 45882Missing in isoform 4. VSP_057599Add
BLAST

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY281366 mRNA. Translation: AAQ16408.1.
AB597184 mRNA. Translation: BAK74843.1.
AB201269 mRNA. Translation: BAE16560.1.
AK021815 mRNA. Translation: BAB13904.1. Different initiation.
AK291357 mRNA. Translation: BAF84046.1.
AC009957 Genomic DNA. No translation available.
AC010130 Genomic DNA. No translation available.
AC010681 Genomic DNA. Translation: AAX93131.1. Different initiation.
AC016910 Genomic DNA. Translation: AAY14764.1.
CH471058 Genomic DNA. Translation: EAX11579.1.
CH471058 Genomic DNA. Translation: EAX11580.1.
CH471058 Genomic DNA. Translation: EAX11581.1.
CH471058 Genomic DNA. Translation: EAX11582.1.
CH471058 Genomic DNA. Translation: EAX11583.1.
CH471058 Genomic DNA. Translation: EAX11584.1.
CH471058 Genomic DNA. Translation: EAX11585.1.
BC017741 mRNA. Translation: AAH17741.1.
BC061699 mRNA. Translation: AAH61699.1.
CCDSiCCDS2185.1. [Q4AE62-2]
CCDS33300.1. [Q4AE62-1]
CCDS63029.1. [Q4AE62-4]
CCDS74582.1. [Q4AE62-6]
CCDS74583.1. [Q4AE62-5]
RefSeqiNP_001006637.1. NM_001006636.3. [Q4AE62-1]
NP_001158101.1. NM_001164629.3. [Q4AE62-1]
NP_001271162.1. NM_001284233.1. [Q4AE62-4]
NP_001271163.1. NM_001284234.1. [Q4AE62-6]
NP_001271164.1. NM_001284235.1. [Q4AE62-3]
NP_001271167.1. NM_001284238.1. [Q4AE62-5]
NP_078935.2. NM_024659.4. [Q4AE62-2]
XP_011510159.1. XM_011511857.1. [Q4AE62-1]
XP_011510162.1. XM_011511860.1. [Q4AE62-4]
XP_011510163.1. XM_011511861.1. [Q4AE62-2]
UniGeneiHs.44780.
Hs.724028.
Hs.724030.
Hs.724213.

Genome annotation databases

EnsembliENST00000241391; ENSP00000241391; ENSG00000121964. [Q4AE62-4]
ENST00000344850; ENSP00000339750; ENSG00000121964. [Q4AE62-1]
ENST00000392867; ENSP00000376606; ENSG00000121964. [Q4AE62-2]
ENST00000392869; ENSP00000376608; ENSG00000121964. [Q4AE62-1]
ENST00000392871; ENSP00000376610; ENSG00000121964. [Q4AE62-4]
ENST00000409214; ENSP00000386581; ENSG00000121964. [Q4AE62-1]
ENST00000463875; ENSP00000437964; ENSG00000121964. [Q4AE62-6]
ENST00000542155; ENSP00000438323; ENSG00000121964. [Q4AE62-1]
ENST00000618778; ENSP00000484990; ENSG00000121964. [Q4AE62-5]
GeneIDi79712.
KEGGihsa:79712.
UCSCiuc002tvo.4. human.
uc002tvp.4. human. [Q4AE62-1]
uc010fno.5. human.
uc061ofi.1. human.

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY281366 mRNA. Translation: AAQ16408.1.
AB597184 mRNA. Translation: BAK74843.1.
AB201269 mRNA. Translation: BAE16560.1.
AK021815 mRNA. Translation: BAB13904.1. Different initiation.
AK291357 mRNA. Translation: BAF84046.1.
AC009957 Genomic DNA. No translation available.
AC010130 Genomic DNA. No translation available.
AC010681 Genomic DNA. Translation: AAX93131.1. Different initiation.
AC016910 Genomic DNA. Translation: AAY14764.1.
CH471058 Genomic DNA. Translation: EAX11579.1.
CH471058 Genomic DNA. Translation: EAX11580.1.
CH471058 Genomic DNA. Translation: EAX11581.1.
CH471058 Genomic DNA. Translation: EAX11582.1.
CH471058 Genomic DNA. Translation: EAX11583.1.
CH471058 Genomic DNA. Translation: EAX11584.1.
CH471058 Genomic DNA. Translation: EAX11585.1.
BC017741 mRNA. Translation: AAH17741.1.
BC061699 mRNA. Translation: AAH61699.1.
CCDSiCCDS2185.1. [Q4AE62-2]
CCDS33300.1. [Q4AE62-1]
CCDS63029.1. [Q4AE62-4]
CCDS74582.1. [Q4AE62-6]
CCDS74583.1. [Q4AE62-5]
RefSeqiNP_001006637.1. NM_001006636.3. [Q4AE62-1]
NP_001158101.1. NM_001164629.3. [Q4AE62-1]
NP_001271162.1. NM_001284233.1. [Q4AE62-4]
NP_001271163.1. NM_001284234.1. [Q4AE62-6]
NP_001271164.1. NM_001284235.1. [Q4AE62-3]
NP_001271167.1. NM_001284238.1. [Q4AE62-5]
NP_078935.2. NM_024659.4. [Q4AE62-2]
XP_011510159.1. XM_011511857.1. [Q4AE62-1]
XP_011510162.1. XM_011511860.1. [Q4AE62-4]
XP_011510163.1. XM_011511861.1. [Q4AE62-2]
UniGeneiHs.44780.
Hs.724028.
Hs.724030.
Hs.724213.

3D structure databases

ProteinModelPortaliQ4AE62.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi122829. 1 interaction.

Protein family/group databases

CAZyiGT4. Glycosyltransferase Family 4.

PTM databases

iPTMnetiQ4AE62.
PhosphoSiteiQ4AE62.

Polymorphism and mutation databases

BioMutaiGTDC1.
DMDMi121946960.

Proteomic databases

MaxQBiQ4AE62.
PaxDbiQ4AE62.
PRIDEiQ4AE62.

Protocols and materials databases

DNASUi79712.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000241391; ENSP00000241391; ENSG00000121964. [Q4AE62-4]
ENST00000344850; ENSP00000339750; ENSG00000121964. [Q4AE62-1]
ENST00000392867; ENSP00000376606; ENSG00000121964. [Q4AE62-2]
ENST00000392869; ENSP00000376608; ENSG00000121964. [Q4AE62-1]
ENST00000392871; ENSP00000376610; ENSG00000121964. [Q4AE62-4]
ENST00000409214; ENSP00000386581; ENSG00000121964. [Q4AE62-1]
ENST00000463875; ENSP00000437964; ENSG00000121964. [Q4AE62-6]
ENST00000542155; ENSP00000438323; ENSG00000121964. [Q4AE62-1]
ENST00000618778; ENSP00000484990; ENSG00000121964. [Q4AE62-5]
GeneIDi79712.
KEGGihsa:79712.
UCSCiuc002tvo.4. human.
uc002tvp.4. human. [Q4AE62-1]
uc010fno.5. human.
uc061ofi.1. human.

Organism-specific databases

CTDi79712.
GeneCardsiGTDC1.
H-InvDBHIX0002488.
HGNCiHGNC:20887. GTDC1.
HPAiHPA036694.
MIMi610165. gene.
neXtProtiNX_Q4AE62.
PharmGKBiPA134892601.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IICG. Eukaryota.
ENOG410ZWWX. LUCA.
GeneTreeiENSGT00390000006631.
HOVERGENiHBG106976.
InParanoidiQ4AE62.
OMAiFMPKHKT.
OrthoDBiEOG7N63MQ.
PhylomeDBiQ4AE62.
TreeFamiTF324818.

Miscellaneous databases

ChiTaRSiGTDC1. human.
GenomeRNAii79712.
PROiQ4AE62.
SOURCEiSearch...

Gene expression databases

BgeeiQ4AE62.
CleanExiHS_GTDC1.
ExpressionAtlasiQ4AE62. baseline and differential.
GenevisibleiQ4AE62. HS.

Family and domain databases

InterProiIPR001296. Glyco_trans_1.
IPR022701. GlycosylTrfase_1_N.
[Graphical view]
PfamiPF12038. DUF3524. 1 hit.
PF00534. Glycos_transf_1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Cloning and expression of human GTDC1 gene (glycosyltransferase-like domain containing 1) from human fetal library."
    Zhao E., Li Y., Fu X., Zhang J.-Y., Zeng H., Zeng L., Lin Y., Chen J., Yin G., Qian J., Ying K., Xie Y., Zhao R.C., Mao Y.-M.
    DNA Cell Biol. 23:183-187(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), TISSUE SPECIFICITY, VARIANT ILE-137.
    Tissue: Brain.
  2. "Remarkable expression in the colon adenocarcinoma of Hmat-Xa, a human mannosyltransferase-like gene, that is homologous to Drosophila gene GC15914."
    Shimono N., Nishimura Y., Kamiguchi H., Nishikawa Y.
    Biosci. Biotechnol. Biochem. 75:1451-1455(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), TISSUE SPECIFICITY.
    Tissue: Fetal brain.
  3. "Cloning and expression of a novel human mannosyltransferase candidate."
    Nishikawa Y., Takahashi T., Saito A., Shimazawa K., Hosaka M.
    Submitted (JAN-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
  4. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1), VARIANT ILE-137.
    Tissue: Brain and Embryo.
  5. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
    Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H.
    , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K.
    Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  6. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  7. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 2 AND 3).
    Tissue: Bone and Kidney.

Entry informationi

Entry nameiGTDC1_HUMAN
AccessioniPrimary (citable) accession number: Q4AE62
Secondary accession number(s): A0A087X2H5
, A8K5P2, D3DP81, G1UFN1, G5EA49, H7BYJ5, Q53SM7, Q53TC5, Q6P7E7, Q6PJB6, Q6WKW6, Q9HAE5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 13, 2007
Last sequence update: September 13, 2005
Last modified: June 8, 2016
This is version 95 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 2
    Human chromosome 2: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.