Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q4ADV7

- RIC1_HUMAN

UniProt

Q4ADV7 - RIC1_HUMAN

Protein

Protein RIC1 homolog

Gene

KIAA1432

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 4 out of 5- Experimental evidence at protein leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 79 (01 Oct 2014)
      Sequence version 2 (26 Feb 2008)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Required for phosphorylation and localization of GJA1.1 Publication

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Protein RIC1 homolog
    Alternative name(s):
    Connexin-43-interacting protein of 150 kDa
    Gene namesi
    Name:KIAA1432
    Synonyms:CIP150
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 9

    Organism-specific databases

    HGNCiHGNC:17686. KIAA1432.

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW

    Keywords - Cellular componenti

    Membrane

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA134884486.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 14231423Protein RIC1 homologPRO_0000320662Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei378 – 3781Phosphoserine1 Publication
    Modified residuei385 – 3851Phosphothreonine1 Publication
    Modified residuei996 – 9961Phosphothreonine1 Publication

    Keywords - PTMi

    Phosphoprotein

    Proteomic databases

    MaxQBiQ4ADV7.
    PaxDbiQ4ADV7.
    PRIDEiQ4ADV7.

    PTM databases

    PhosphoSiteiQ4ADV7.

    Expressioni

    Tissue specificityi

    Present in kidney and various cell lines (at protein level). Widely expressed at low level.2 Publications

    Gene expression databases

    ArrayExpressiQ4ADV7.
    BgeeiQ4ADV7.
    CleanExiHS_KIAA1432.
    GenevestigatoriQ4ADV7.

    Organism-specific databases

    HPAiHPA051578.

    Interactioni

    Subunit structurei

    Interacts with GJA1.1 Publication

    Protein-protein interaction databases

    BioGridi121640. 2 interactions.
    IntActiQ4ADV7. 1 interaction.
    STRINGi9606.ENSP00000402240.

    Structurei

    3D structure databases

    ProteinModelPortaliQ4ADV7.
    SMRiQ4ADV7. Positions 253-339.
    ModBaseiSearch...
    MobiDBiSearch...

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei1267 – 128721HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Repeati64 – 10340WD 1Add
    BLAST
    Repeati304 – 34340WD 2Add
    BLAST

    Sequence similaritiesi

    Belongs to the RIC1 family.Curated
    Contains 2 WD repeats.Curated

    Keywords - Domaini

    Repeat, Transmembrane, Transmembrane helix, WD repeat

    Phylogenomic databases

    eggNOGiNOG239520.
    HOGENOMiHOG000047604.
    HOVERGENiHBG091027.
    InParanoidiQ4ADV7.
    OMAiQSVENVW.
    OrthoDBiEOG7ZSHS3.
    PhylomeDBiQ4ADV7.
    TreeFamiTF105927.

    Family and domain databases

    Gene3Di2.130.10.10. 2 hits.
    InterProiIPR009771. Ribosome_control_1.
    IPR015943. WD40/YVTN_repeat-like_dom.
    IPR017986. WD40_repeat_dom.
    [Graphical view]
    PfamiPF07064. RIC1. 1 hit.
    [Graphical view]
    SUPFAMiSSF50978. SSF50978. 2 hits.

    Sequences (3)i

    Sequence statusi: Complete.

    This entry describes 3 isoformsi produced by alternative splicing. Align

    Isoform 1 (identifier: Q4ADV7-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MYFLSGWPKR LLCPLGSPAE APFHVQSDPQ RAFFAVLAAA RLSIWYSRPS     50
    VLIVTYKEPA KSSTQFGSYK QAEWRPDSTM IAVSTANGYI LFFHITSTRG 100
    DKYLYEPVYP KGSPQMKGTP HFKEEQCAPA LNLEMRKILD LQAPIMSLQS 150
    VLEDLLVATS DGLLHLIHWE GMTNGRKAIN LCTVPFSVDL QSSRVGSFLG 200
    FTDVHIRDME YCATLDGFAV VFNDGKVGFI TPVSSRFTAE QLHGVWPQDV 250
    VDGTCVAVNN KYRLMAFGCV SGSVQVYTID NSTGAMLLSH KLELTAKQYP 300
    DIWNKTGAVK LMRWSPDNSV VIVTWEYGGL SLWSVFGAQL ICTLGGDFAY 350
    RSDGTKKDPL KINSMSWGAE GYHLWVISGF GSQNTEIESD LRSVVKQPSI 400
    LLFQFIKSVL TVNPCMSNQE QVLLQGEDRL YLNCGEASQT QNPRSSSTHS 450
    EHKPSREKSP FADGGLESQG LSTLLGHRHW HVVQISSTYL ESNWPIRFSA 500
    IDKLGQNIAV VGKFGFAHYS LLTKKWKLFG NITQEQNMIV TGGLAWWNDF 550
    MVLACYNIND RQEELRVYLR TSNLDNAFAH VTKAQAETLL LSVFQDMVIV 600
    FRADCSICLY SIERKSDGPN TTAGIQVLQE VSMSRYIPHP FLVVSVTLTS 650
    VSTENGITLK MPQQARGAES IMLNLAGQLI MMQRDRSGPQ IREKDSNPNN 700
    QRKLLPFCPP VVLAQSVENV WTTCRANKQK RHLLEALWLS CGGAGMKVWL 750
    PLFPRDHRKP HSFLSQRIML PFHINIYPLA VLFEDALVLG AVNDTLLYDS 800
    LYTRNNAREQ LEVLFPFCVV ERTSQIYLHH ILRQLLVRNL GEQALLLAQS 850
    CATLPYFPHV LELMLHEVLE EEATSREPIP DPLLPTVAKF ITEFPLFLQT 900
    VVHCARKTEY ALWNYLFAAV GNPKDLFEEC LMAQDLDTAA SYLIILQNME 950
    VPAVSRQHAT LLFNTALEQG KWDLCRHMIR FLKAIGSGES ETPPSTPTAQ 1000
    EPSSSGGFEF FRNRSISLSQ SAENVPASKF SLQKTLSMPS GPSGKRWSKD 1050
    SDCAENMYID MMLWRHARRL LEDVRLKDLG CFAAQLGFEL ISWLCKERTR 1100
    AARVDNFVIA LKRLHKDFLW PLPIIPASSI SSPFKNGKYR TVGEQLLKSQ 1150
    SADPFLNLEM DAGISNIQRS QSWLSNIGPT HHEIDTASSH GPQMQDAFLS 1200
    PLSNKGDECS IGSATDLTES SSMVDGDWTM VDENFSTLSL TQSELEHISM 1250
    ELASKGPHKS QVQLRYLLHI FMEAGCLDWC IVIGLILRES SIINQILVIT 1300
    QSSEVDGEML QNIKTGLHAV DRWASTDCPG YKPFLNIIKP QLQKLSEITE 1350
    EQVQPDAFQP ITMGKTPEQT SPRAEESRGS SSHGSIPQGE VGSSNMVSRK 1400
    EEDTAQAEEE EPFQDGTYDC SVS 1423
    Length:1,423
    Mass (Da):159,301
    Last modified:February 26, 2008 - v2
    Checksum:i9F6F43F572021930
    GO
    Isoform 2 (identifier: Q4ADV7-2) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         1142-1165: VGEQLLKSQSADPFLNLEMDAGIS → GNVDFMSLVQGELYFTPCIYTFCY
         1166-1423: Missing.

    Note: No experimental confirmation available.

    Show »
    Length:1,165
    Mass (Da):131,167
    Checksum:iFCEA626180A59C3E
    GO
    Isoform 3 (identifier: Q4ADV7-3) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         498-534: Missing.

    Note: No experimental confirmation available.

    Show »
    Length:1,386
    Mass (Da):155,177
    Checksum:i9EAA63EE7FCDFDA9
    GO

    Sequence cautioni

    The sequence AAI36617.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.
    The sequence AAI44297.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.
    The sequence BAB14150.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.
    The sequence BAE16982.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.
    The sequence CAB66809.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.
    The sequence CAI95003.1 differs from that shown. Reason: Erroneous gene model prediction.
    The sequence CAI95004.1 differs from that shown. Reason: Erroneous gene model prediction.

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti659 – 6591L → F in BAB84976. (PubMed:10718198)Curated
    Sequence conflicti664 – 6641Q → E in BAB84976. (PubMed:10718198)Curated
    Sequence conflicti1012 – 10121R → G in AAH30576. (PubMed:12168954)Curated

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei498 – 53437Missing in isoform 3. 1 PublicationVSP_042408Add
    BLAST
    Alternative sequencei1142 – 116524VGEQL…DAGIS → GNVDFMSLVQGELYFTPCIY TFCY in isoform 2. 2 PublicationsVSP_031706Add
    BLAST
    Alternative sequencei1166 – 1423258Missing in isoform 2. 2 PublicationsVSP_031707Add
    BLAST

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL136980 Genomic DNA. Translation: CAI95003.1. Sequence problems.
    AL136980 Genomic DNA. Translation: CAI95004.1. Sequence problems.
    AL354744 Genomic DNA. No translation available.
    CH471071 Genomic DNA. Translation: EAW58760.1.
    AL136875 mRNA. Translation: CAB66809.1. Different initiation.
    AB205401 mRNA. Translation: BAE16982.1. Different initiation.
    AK022642 mRNA. Translation: BAB14150.1. Different initiation.
    AB037853 mRNA. Translation: BAA92670.2.
    AK074150 mRNA. Translation: BAB84976.1.
    BC030576 mRNA. Translation: AAH30576.1.
    BC136616 mRNA. Translation: AAI36617.1. Different initiation.
    BC144296 mRNA. Translation: AAI44297.1. Different initiation.
    CCDSiCCDS34982.2. [Q4ADV7-1]
    CCDS47949.2. [Q4ADV7-2]
    RefSeqiNP_001129392.2. NM_001135920.2. [Q4ADV7-2]
    NP_001193486.1. NM_001206557.1. [Q4ADV7-3]
    NP_065880.2. NM_020829.3. [Q4ADV7-1]
    UniGeneiHs.211520.
    Hs.661509.

    Genome annotation databases

    EnsembliENST00000251879; ENSP00000251879; ENSG00000107036. [Q4ADV7-2]
    ENST00000414202; ENSP00000416696; ENSG00000107036. [Q4ADV7-1]
    ENST00000418622; ENSP00000402240; ENSG00000107036.
    GeneIDi57589.
    KEGGihsa:57589.
    UCSCiuc003zjh.4. human. [Q4ADV7-2]
    uc003zji.4. human. [Q4ADV7-1]
    uc003zjl.4. human. [Q4ADV7-3]

    Polymorphism databases

    DMDMi182702127.

    Keywords - Coding sequence diversityi

    Alternative splicing

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL136980 Genomic DNA. Translation: CAI95003.1 . Sequence problems.
    AL136980 Genomic DNA. Translation: CAI95004.1 . Sequence problems.
    AL354744 Genomic DNA. No translation available.
    CH471071 Genomic DNA. Translation: EAW58760.1 .
    AL136875 mRNA. Translation: CAB66809.1 . Different initiation.
    AB205401 mRNA. Translation: BAE16982.1 . Different initiation.
    AK022642 mRNA. Translation: BAB14150.1 . Different initiation.
    AB037853 mRNA. Translation: BAA92670.2 .
    AK074150 mRNA. Translation: BAB84976.1 .
    BC030576 mRNA. Translation: AAH30576.1 .
    BC136616 mRNA. Translation: AAI36617.1 . Different initiation.
    BC144296 mRNA. Translation: AAI44297.1 . Different initiation.
    CCDSi CCDS34982.2. [Q4ADV7-1 ]
    CCDS47949.2. [Q4ADV7-2 ]
    RefSeqi NP_001129392.2. NM_001135920.2. [Q4ADV7-2 ]
    NP_001193486.1. NM_001206557.1. [Q4ADV7-3 ]
    NP_065880.2. NM_020829.3. [Q4ADV7-1 ]
    UniGenei Hs.211520.
    Hs.661509.

    3D structure databases

    ProteinModelPortali Q4ADV7.
    SMRi Q4ADV7. Positions 253-339.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 121640. 2 interactions.
    IntActi Q4ADV7. 1 interaction.
    STRINGi 9606.ENSP00000402240.

    PTM databases

    PhosphoSitei Q4ADV7.

    Polymorphism databases

    DMDMi 182702127.

    Proteomic databases

    MaxQBi Q4ADV7.
    PaxDbi Q4ADV7.
    PRIDEi Q4ADV7.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000251879 ; ENSP00000251879 ; ENSG00000107036 . [Q4ADV7-2 ]
    ENST00000414202 ; ENSP00000416696 ; ENSG00000107036 . [Q4ADV7-1 ]
    ENST00000418622 ; ENSP00000402240 ; ENSG00000107036 .
    GeneIDi 57589.
    KEGGi hsa:57589.
    UCSCi uc003zjh.4. human. [Q4ADV7-2 ]
    uc003zji.4. human. [Q4ADV7-1 ]
    uc003zjl.4. human. [Q4ADV7-3 ]

    Organism-specific databases

    CTDi 57589.
    GeneCardsi GC09P005629.
    H-InvDB HIX0007902.
    HGNCi HGNC:17686. KIAA1432.
    HPAi HPA051578.
    MIMi 610354. gene.
    neXtProti NX_Q4ADV7.
    PharmGKBi PA134884486.
    HUGEi Search...
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG239520.
    HOGENOMi HOG000047604.
    HOVERGENi HBG091027.
    InParanoidi Q4ADV7.
    OMAi QSVENVW.
    OrthoDBi EOG7ZSHS3.
    PhylomeDBi Q4ADV7.
    TreeFami TF105927.

    Miscellaneous databases

    ChiTaRSi KIAA1432. human.
    GenomeRNAii 57589.
    NextBioi 64170.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q4ADV7.
    Bgeei Q4ADV7.
    CleanExi HS_KIAA1432.
    Genevestigatori Q4ADV7.

    Family and domain databases

    Gene3Di 2.130.10.10. 2 hits.
    InterProi IPR009771. Ribosome_control_1.
    IPR015943. WD40/YVTN_repeat-like_dom.
    IPR017986. WD40_repeat_dom.
    [Graphical view ]
    Pfami PF07064. RIC1. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50978. SSF50978. 2 hits.
    ProtoNeti Search...

    Publicationsi

    1. "DNA sequence and analysis of human chromosome 9."
      Humphray S.J., Oliver K., Hunt A.R., Plumb R.W., Loveland J.E., Howe K.L., Andrews T.D., Searle S., Hunt S.E., Scott C.E., Jones M.C., Ainscough R., Almeida J.P., Ambrose K.D., Ashwell R.I.S., Babbage A.K., Babbage S., Bagguley C.L.
      , Bailey J., Banerjee R., Barker D.J., Barlow K.F., Bates K., Beasley H., Beasley O., Bird C.P., Bray-Allen S., Brown A.J., Brown J.Y., Burford D., Burrill W., Burton J., Carder C., Carter N.P., Chapman J.C., Chen Y., Clarke G., Clark S.Y., Clee C.M., Clegg S., Collier R.E., Corby N., Crosier M., Cummings A.T., Davies J., Dhami P., Dunn M., Dutta I., Dyer L.W., Earthrowl M.E., Faulkner L., Fleming C.J., Frankish A., Frankland J.A., French L., Fricker D.G., Garner P., Garnett J., Ghori J., Gilbert J.G.R., Glison C., Grafham D.V., Gribble S., Griffiths C., Griffiths-Jones S., Grocock R., Guy J., Hall R.E., Hammond S., Harley J.L., Harrison E.S.I., Hart E.A., Heath P.D., Henderson C.D., Hopkins B.L., Howard P.J., Howden P.J., Huckle E., Johnson C., Johnson D., Joy A.A., Kay M., Keenan S., Kershaw J.K., Kimberley A.M., King A., Knights A., Laird G.K., Langford C., Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C., Lloyd D.M., Lovell J., Martin S., Mashreghi-Mohammadi M., Matthews L., McLaren S., McLay K.E., McMurray A., Milne S., Nickerson T., Nisbett J., Nordsiek G., Pearce A.V., Peck A.I., Porter K.M., Pandian R., Pelan S., Phillimore B., Povey S., Ramsey Y., Rand V., Scharfe M., Sehra H.K., Shownkeen R., Sims S.K., Skuce C.D., Smith M., Steward C.A., Swarbreck D., Sycamore N., Tester J., Thorpe A., Tracey A., Tromans A., Thomas D.W., Wall M., Wallis J.M., West A.P., Whitehead S.L., Willey D.L., Williams S.A., Wilming L., Wray P.W., Young L., Ashurst J.L., Coulson A., Blocker H., Durbin R.M., Sulston J.E., Hubbard T., Jackson M.J., Bentley D.R., Beck S., Rogers J., Dunham I.
      Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 7-1423 (ISOFORM 2).
      Tissue: Testis.
    4. "Molecular cloning and functional analysis of a novel Cx43 partner protein CIP150."
      Akiyama M., Ishida N., Ogawa T., Yogo K., Takeya T.
      Biochem. Biophys. Res. Commun. 335:1264-1271(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 73-1423 (ISOFORM 1), FUNCTION, TISSUE SPECIFICITY, INTERACTION WITH GJA1.
      Tissue: Placenta.
    5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 73-1423 (ISOFORMS 1 AND 3).
      Tissue: Bone marrow.
    6. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 531-1423 (ISOFORM 2).
      Tissue: Teratocarcinoma.
    7. "Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro."
      Nagase T., Kikuno R., Ishikawa K., Hirosawa M., Ohara O.
      DNA Res. 7:65-73(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 628-1423 (ISOFORM 1), TISSUE SPECIFICITY.
      Tissue: Brain.
    8. "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones."
      Nakajima D., Okazaki N., Yamakawa H., Kikuno R., Ohara O., Nagase T.
      DNA Res. 9:99-106(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: SEQUENCE REVISION.
    9. "The nucleotide sequence of a long cDNA clone isolated from human spleen."
      Jikuya H., Takano J., Nomura N., Kikuno R., Nagase T., Ohara O.
      Submitted (JAN-2002) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 656-1423.
      Tissue: Spleen.
    10. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-996, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Cervix carcinoma.
    11. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
      Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J., Mohammed S.
      Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    12. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
      Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K.
      Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-378 AND THR-385, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Leukemic T-cell.
    13. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
      Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.
      Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

    Entry informationi

    Entry nameiRIC1_HUMAN
    AccessioniPrimary (citable) accession number: Q4ADV7
    Secondary accession number(s): B2RN24
    , B7ZM67, G5E932, Q4VXJ8, Q4VXJ9, Q76MT5, Q8N6E0, Q8TEH4, Q9H0A5, Q9H9S1
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 26, 2008
    Last sequence update: February 26, 2008
    Last modified: October 1, 2014
    This is version 79 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 9
      Human chromosome 9: entries, gene names and cross-references to MIM
    2. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3