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Protein
Submitted name:

TACI

Gene

TACI

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

ReceptorImported

Names & Taxonomyi

Protein namesi
Submitted name:
TACIImported
Submitted name:
Tumor necrosis factor receptor superfamily, member 13BImported
Submitted name:
Tumor necrosis factor receptor superfamily, member 13B, isoform CRA_aImported
Gene namesi
Name:TACIImported
Synonyms:TNFRSF13BImported
ORF Names:hCG_28297Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei161 – 18626HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA38509.

Expressioni

Gene expression databases

ExpressionAtlasiQ4ACX1. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000261652.

Structurei

3D structure databases

SMRiQ4ACX1. Positions 68-109.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini37 – 6731TACI-CRD2InterPro annotationAdd
BLAST
Domaini69 – 10739TACI-CRD2InterPro annotationAdd
BLAST

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IHJ8. Eukaryota.
ENOG410Z545. LUCA.
GeneTreeiENSGT00390000013910.
HOVERGENiHBG058015.
KOiK05150.
OMAiCHTRTTV.
PhylomeDBiQ4ACX1.

Family and domain databases

InterProiIPR015384. TACI_Cys-rich-dom.
IPR022317. TNFR_13B.
[Graphical view]
PfamiPF09305. TACI-CRD2. 2 hits.
[Graphical view]
PRINTSiPR01963. TNFACTORR13B.

Sequencei

Sequence statusi: Complete.

Q4ACX1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSGLGRSRRG GRSRVDQEER FPQGLWTGVA MRSCPEEQYW DPLLGTCMSC
60 70 80 90 100
KTICNHQSQR TCAAFCRSLS CRKEQGKFYD HLLRDCISCA SICGQHPKQC
110 120 130 140 150
AYFCENKLRS PVNLPPELRR QRSGEVENNS DNSGRYQGLE HRGSEASPAL
160 170 180 190 200
PGLKLSADQV ALVYSTLGLC LCAVLCCFLV AVACFLKKRG DPCSCQPRSR
210 220 230 240 250
PRQSPAKSSQ DHAMEAGSPV STSPEPVETC SFCFPECRAP TQESAVTPGT
260 270 280 290
PDPTCAGRWG CHTRTTVLQP CPHIPDSGLG IVCVPAQEGG PGA
Length:293
Mass (Da):31,816
Last modified:September 13, 2005 - v1
Checksum:i411799F3DE17A5EB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EF064711 Genomic DNA. Translation: ABK41894.1.
AB222991 Genomic DNA. Translation: BAE16555.1.
CH471196 Genomic DNA. Translation: EAW55728.1.
RefSeqiNP_036584.1. NM_012452.2.
UniGeneiHs.158341.

Genome annotation databases

GeneIDi23495.
KEGGihsa:23495.
UCSCiuc002gqs.2. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EF064711 Genomic DNA. Translation: ABK41894.1.
AB222991 Genomic DNA. Translation: BAE16555.1.
CH471196 Genomic DNA. Translation: EAW55728.1.
RefSeqiNP_036584.1. NM_012452.2.
UniGeneiHs.158341.

3D structure databases

SMRiQ4ACX1. Positions 68-109.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000261652.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi23495.
KEGGihsa:23495.
UCSCiuc002gqs.2. human.

Organism-specific databases

CTDi23495.
PharmGKBiPA38509.

Phylogenomic databases

eggNOGiENOG410IHJ8. Eukaryota.
ENOG410Z545. LUCA.
GeneTreeiENSGT00390000013910.
HOVERGENiHBG058015.
KOiK05150.
OMAiCHTRTTV.
PhylomeDBiQ4ACX1.

Miscellaneous databases

ChiTaRSiTNFRSF13B. human.
GenomeRNAii23495.
NextBioi45863.

Gene expression databases

ExpressionAtlasiQ4ACX1. baseline and differential.

Family and domain databases

InterProiIPR015384. TACI_Cys-rich-dom.
IPR022317. TNFR_13B.
[Graphical view]
PfamiPF09305. TACI-CRD2. 2 hits.
[Graphical view]
PRINTSiPR01963. TNFACTORR13B.
ProtoNetiSearch...

Publicationsi

  1. "The sequence of the human genome."
    Venter J.C., Adams M.D., Myers E.W., Li P.W., Mural R.J., Sutton G.G., Smith H.O., Yandell M., Evans C.A., Holt R.A., Gocayne J.D., Amanatides P., Ballew R.M., Huson D.H., Wortman J.R., Zhang Q., Kodira C.D., Zheng X.H.
    , Chen L., Skupski M., Subramanian G., Thomas P.D., Zhang J., Gabor Miklos G.L., Nelson C., Broder S., Clark A.G., Nadeau J., McKusick V.A., Zinder N., Levine A.J., Roberts R.J., Simon M., Slayman C., Hunkapiller M., Bolanos R., Delcher A., Dew I., Fasulo D., Flanigan M., Florea L., Halpern A., Hannenhalli S., Kravitz S., Levy S., Mobarry C., Reinert K., Remington K., Abu-Threideh J., Beasley E., Biddick K., Bonazzi V., Brandon R., Cargill M., Chandramouliswaran I., Charlab R., Chaturvedi K., Deng Z., Di Francesco V., Dunn P., Eilbeck K., Evangelista C., Gabrielian A.E., Gan W., Ge W., Gong F., Gu Z., Guan P., Heiman T.J., Higgins M.E., Ji R.R., Ke Z., Ketchum K.A., Lai Z., Lei Y., Li Z., Li J., Liang Y., Lin X., Lu F., Merkulov G.V., Milshina N., Moore H.M., Naik A.K., Narayan V.A., Neelam B., Nusskern D., Rusch D.B., Salzberg S., Shao W., Shue B., Sun J., Wang Z., Wang A., Wang X., Wang J., Wei M., Wides R., Xiao C., Yan C., Yao A., Ye J., Zhan M., Zhang W., Zhang H., Zhao Q., Zheng L., Zhong F., Zhong W., Zhu S., Zhao S., Gilbert D., Baumhueter S., Spier G., Carter C., Cravchik A., Woodage T., Ali F., An H., Awe A., Baldwin D., Baden H., Barnstead M., Barrow I., Beeson K., Busam D., Carver A., Center A., Cheng M.L., Curry L., Danaher S., Davenport L., Desilets R., Dietz S., Dodson K., Doup L., Ferriera S., Garg N., Gluecksmann A., Hart B., Haynes J., Haynes C., Heiner C., Hladun S., Hostin D., Houck J., Howland T., Ibegwam C., Johnson J., Kalush F., Kline L., Koduru S., Love A., Mann F., May D., McCawley S., McIntosh T., McMullen I., Moy M., Moy L., Murphy B., Nelson K., Pfannkoch C., Pratts E., Puri V., Qureshi H., Reardon M., Rodriguez R., Rogers Y.H., Romblad D., Ruhfel B., Scott R., Sitter C., Smallwood M., Stewart E., Strong R., Suh E., Thomas R., Tint N.N., Tse S., Vech C., Wang G., Wetter J., Williams S., Williams M., Windsor S., Winn-Deen E., Wolfe K., Zaveri J., Zaveri K., Abril J.F., Guigo R., Campbell M.J., Sjolander K.V., Karlak B., Kejariwal A., Mi H., Lazareva B., Hatton T., Narechania A., Diemer K., Muruganujan A., Guo N., Sato S., Bafna V., Istrail S., Lippert R., Schwartz R., Walenz B., Yooseph S., Allen D., Basu A., Baxendale J., Blick L., Caminha M., Carnes-Stine J., Caulk P., Chiang Y.H., Coyne M., Dahlke C., Mays A., Dombroski M., Donnelly M., Ely D., Esparham S., Fosler C., Gire H., Glanowski S., Glasser K., Glodek A., Gorokhov M., Graham K., Gropman B., Harris M., Heil J., Henderson S., Hoover J., Jennings D., Jordan C., Jordan J., Kasha J., Kagan L., Kraft C., Levitsky A., Lewis M., Liu X., Lopez J., Ma D., Majoros W., McDaniel J., Murphy S., Newman M., Nguyen T., Nguyen N., Nodell M., Pan S., Peck J., Peterson M., Rowe W., Sanders R., Scott J., Simpson M., Smith T., Sprague A., Stockwell T., Turner R., Venter E., Wang M., Wen M., Wu D., Wu M., Xia A., Zandieh A., Zhu X.
    Science 291:1304-1351(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  2. "New polymorphisms of human BAFF-R gene."
    Kawasaki A., Tsuchiya N., Kusaoi M., Murakami Y., Fukazawa T., Matsuta K., Hashimoto H., Tokunaga K.
    Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  3. "New polymorphisms of human TACI gene."
    Kawasaki A., Tsuchiya N., Kusaoi M., Murakami T., Fukazawa T., Matsuta H., Hashimoto H., Tokunaga K.
    Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  4. Cited for: NUCLEOTIDE SEQUENCE.
  5. Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ4ACX1_HUMAN
AccessioniPrimary (citable) accession number: Q4ACX1
Entry historyi
Integrated into UniProtKB/TrEMBL: September 13, 2005
Last sequence update: September 13, 2005
Last modified: May 11, 2016
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.