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Q4ACT8

- Q4ACT8_PIG

UniProt

Q4ACT8 - Q4ACT8_PIG

Protein
Submitted name:

Testicular angiotensin-I converting enzyme

Gene

tACE

Organism
Sus scrofa (Pig)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 44 (01 Oct 2014)
      Sequence version 2 (08 Nov 2005)
      Previous versions | rss
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    Functioni

    Cofactori

    Binds 1 zinc ion per subunit.UniRule annotation
    Binds 2 zinc ions per subunit.UniRule annotation

    GO - Molecular functioni

    1. metallopeptidase activity Source: InterPro
    2. peptidyl-dipeptidase activity Source: InterPro

    Keywords - Molecular functioni

    CarboxypeptidaseUniRule annotation, Hydrolase, MetalloproteaseUniRule annotation, Protease

    Keywords - Ligandi

    Metal-bindingUniRule annotation, ZincUniRule annotation

    Protein family/group databases

    MEROPSiM02.001.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Testicular angiotensin-I converting enzymeImported
    Gene namesi
    Name:tACEImported
    OrganismiSus scrofa (Pig)Imported
    Taxonomic identifieri9823 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaSuinaSuidaeSus

    Subcellular locationi

    GO - Cellular componenti

    1. membrane Source: InterPro

    PTM / Processingi

    Keywords - PTMi

    GlycoproteinUniRule annotation

    Structurei

    3D structure databases

    ProteinModelPortaliQ4ACT8.
    SMRiQ4ACT8. Positions 84-667.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the peptidase M2 family.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000292210.
    HOVERGENiHBG103676.
    KOiK01283.

    Family and domain databases

    InterProiIPR001548. Peptidase_M2.
    [Graphical view]
    PANTHERiPTHR10514. PTHR10514. 1 hit.
    PfamiPF01401. Peptidase_M2. 1 hit.
    [Graphical view]
    PRINTSiPR00791. PEPDIPTASEA.

    Sequencei

    Sequence statusi: Complete.

    Q4ACT8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MGQGWAAPGL PCLLLLLLLC CGRPLLVPGQ GTTSQVTDIQ RTTSQATTSG    50
    QATTSSQATT SSQTTTSHST TSSLKTQSPN LVSDEAEASK FVEEYDRRSQ 100
    VVLNEYAEAN WDYNTNITAE GSKRVLEKST QMANHTVKYG IWARKFDVAN 150
    IQNFTLKRMI KKIQDLERAA LPFKELEEYN QILLDMETAY SVASVCHANS 200
    TCLQLEPDLT NLMDTSRSYE ELLWAWKGWR DKVGRAILPL FPKYVELTNK 250
    AARLNGYEDG GDAWRAAYEM PFLEQELEQL FQELQPLYLN LHAYVRRALH 300
    HHYGPEHINL EGPIPAHLLG NMWAQTWSNI YDLVVPFPSA SKMDASEAMI 350
    NQGWTPQKMF KEADNFFTSL GLLPVPPEFW NKSMLEKPTD GREVVCHASA 400
    WDFFNGKDFR IKQCTTVNME DLVVAHHEMG HIQYFMQYKD LPVTFREGAN 450
    PGFHEAIGDV LALSVSTPKH LRSINLLKSE DDGYEEDINF LMKMALDKVA 500
    FVPFSYLVDQ WRWRVFDRSI TKENYNQEWW SLRLKYQGLC PPVARSQGDF 550
    DPGAKFHIPS SVPYIRYFVS FIIQFQFHEA LCQAAGHKGP LHKCDIYQSK 600
    EAGRRLADAM KLGLSKPWPE AMQLITGQPN VSASAMMTYF KPLLDWLVTE 650
    NGRHGEKLGW PQYNWTPNSA RLEGSFAGTG RVNFLGLNLE EQQARVGQWV 700
    LLFLGVTLLV ATMGLTQRLF SIRHQILRRT HRGPQFGSEV ELRHS 745
    Length:745
    Mass (Da):84,801
    Last modified:November 8, 2005 - v2
    Checksum:i98C5784DAB9FC4B2
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB231334 mRNA. Translation: BAE16967.2.
    RefSeqiNP_001028187.2. NM_001033015.2.
    UniGeneiSsc.25769.

    Genome annotation databases

    GeneIDi613133.
    KEGGissc:613133.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB231334 mRNA. Translation: BAE16967.2 .
    RefSeqi NP_001028187.2. NM_001033015.2.
    UniGenei Ssc.25769.

    3D structure databases

    ProteinModelPortali Q4ACT8.
    SMRi Q4ACT8. Positions 84-667.
    ModBasei Search...
    MobiDBi Search...

    Chemistry

    ChEMBLi CHEMBL3432.

    Protein family/group databases

    MEROPSi M02.001.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 613133.
    KEGGi ssc:613133.

    Organism-specific databases

    CTDi 1636.

    Phylogenomic databases

    HOGENOMi HOG000292210.
    HOVERGENi HBG103676.
    KOi K01283.

    Family and domain databases

    InterProi IPR001548. Peptidase_M2.
    [Graphical view ]
    PANTHERi PTHR10514. PTHR10514. 1 hit.
    Pfami PF01401. Peptidase_M2. 1 hit.
    [Graphical view ]
    PRINTSi PR00791. PEPDIPTASEA.
    ProtoNeti Search...

    Publicationsi

    1. "Porcine germinal angiotensin I-converting enzyme: isolation, characterization and molecular cloning."
      Takeuchi K., Araki H., Sakaue T., Yamamoto Y., Fujiwara M., Nishi K., Ohkubo I.
      Comp. Biochem. Physiol. B, Biochem. Mol. Biol. 146:215-226(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: TestisImported.

    Entry informationi

    Entry nameiQ4ACT8_PIG
    AccessioniPrimary (citable) accession number: Q4ACT8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 13, 2005
    Last sequence update: November 8, 2005
    Last modified: October 1, 2014
    This is version 44 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)