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Q4ACT8

- Q4ACT8_PIG

UniProt

Q4ACT8 - Q4ACT8_PIG

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Protein
Submitted name:

Testicular angiotensin-I converting enzyme

Gene

tACE

Organism
Sus scrofa (Pig)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli

Functioni

Cofactori

Binds 1 zinc ion per subunit.UniRule annotation
Binds 2 zinc ions per subunit.UniRule annotation

GO - Molecular functioni

  1. carboxypeptidase activity Source: UniProtKB-KW
  2. metal ion binding Source: UniProtKB-KW
  3. metallopeptidase activity Source: UniProtKB-KW
  4. peptidyl-dipeptidase activity Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

CarboxypeptidaseUniRule annotation, Hydrolase, MetalloproteaseUniRule annotation, Protease

Keywords - Ligandi

Metal-bindingUniRule annotation, ZincUniRule annotation

Protein family/group databases

MEROPSiM02.005.

Names & Taxonomyi

Protein namesi
Submitted name:
Testicular angiotensin-I converting enzymeImported
Gene namesi
Name:tACEImported
OrganismiSus scrofa (Pig)Imported
Taxonomic identifieri9823 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaSuinaSuidaeSus

Subcellular locationi

GO - Cellular componenti

  1. membrane Source: InterPro
Complete GO annotation...

PTM / Processingi

Keywords - PTMi

GlycoproteinUniRule annotation

Structurei

3D structure databases

ProteinModelPortaliQ4ACT8.
SMRiQ4ACT8. Positions 84-667.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase M2 family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000292210.
HOVERGENiHBG103676.
KOiK01283.

Family and domain databases

InterProiIPR001548. Peptidase_M2.
[Graphical view]
PANTHERiPTHR10514. PTHR10514. 1 hit.
PfamiPF01401. Peptidase_M2. 1 hit.
[Graphical view]
PRINTSiPR00791. PEPDIPTASEA.

Sequencei

Sequence statusi: Complete.

Q4ACT8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MGQGWAAPGL PCLLLLLLLC CGRPLLVPGQ GTTSQVTDIQ RTTSQATTSG
60 70 80 90 100
QATTSSQATT SSQTTTSHST TSSLKTQSPN LVSDEAEASK FVEEYDRRSQ
110 120 130 140 150
VVLNEYAEAN WDYNTNITAE GSKRVLEKST QMANHTVKYG IWARKFDVAN
160 170 180 190 200
IQNFTLKRMI KKIQDLERAA LPFKELEEYN QILLDMETAY SVASVCHANS
210 220 230 240 250
TCLQLEPDLT NLMDTSRSYE ELLWAWKGWR DKVGRAILPL FPKYVELTNK
260 270 280 290 300
AARLNGYEDG GDAWRAAYEM PFLEQELEQL FQELQPLYLN LHAYVRRALH
310 320 330 340 350
HHYGPEHINL EGPIPAHLLG NMWAQTWSNI YDLVVPFPSA SKMDASEAMI
360 370 380 390 400
NQGWTPQKMF KEADNFFTSL GLLPVPPEFW NKSMLEKPTD GREVVCHASA
410 420 430 440 450
WDFFNGKDFR IKQCTTVNME DLVVAHHEMG HIQYFMQYKD LPVTFREGAN
460 470 480 490 500
PGFHEAIGDV LALSVSTPKH LRSINLLKSE DDGYEEDINF LMKMALDKVA
510 520 530 540 550
FVPFSYLVDQ WRWRVFDRSI TKENYNQEWW SLRLKYQGLC PPVARSQGDF
560 570 580 590 600
DPGAKFHIPS SVPYIRYFVS FIIQFQFHEA LCQAAGHKGP LHKCDIYQSK
610 620 630 640 650
EAGRRLADAM KLGLSKPWPE AMQLITGQPN VSASAMMTYF KPLLDWLVTE
660 670 680 690 700
NGRHGEKLGW PQYNWTPNSA RLEGSFAGTG RVNFLGLNLE EQQARVGQWV
710 720 730 740
LLFLGVTLLV ATMGLTQRLF SIRHQILRRT HRGPQFGSEV ELRHS
Length:745
Mass (Da):84,801
Last modified:November 8, 2005 - v2
Checksum:i98C5784DAB9FC4B2
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB231334 mRNA. Translation: BAE16967.2.
RefSeqiNP_001028187.2. NM_001033015.2.
UniGeneiSsc.25769.

Genome annotation databases

GeneIDi613133.
KEGGissc:613133.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB231334 mRNA. Translation: BAE16967.2 .
RefSeqi NP_001028187.2. NM_001033015.2.
UniGenei Ssc.25769.

3D structure databases

ProteinModelPortali Q4ACT8.
SMRi Q4ACT8. Positions 84-667.
ModBasei Search...
MobiDBi Search...

Chemistry

ChEMBLi CHEMBL3432.

Protein family/group databases

MEROPSi M02.005.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 613133.
KEGGi ssc:613133.

Organism-specific databases

CTDi 1636.

Phylogenomic databases

HOGENOMi HOG000292210.
HOVERGENi HBG103676.
KOi K01283.

Family and domain databases

InterProi IPR001548. Peptidase_M2.
[Graphical view ]
PANTHERi PTHR10514. PTHR10514. 1 hit.
Pfami PF01401. Peptidase_M2. 1 hit.
[Graphical view ]
PRINTSi PR00791. PEPDIPTASEA.
ProtoNeti Search...

Publicationsi

  1. "Porcine germinal angiotensin I-converting enzyme: isolation, characterization and molecular cloning."
    Takeuchi K., Araki H., Sakaue T., Yamamoto Y., Fujiwara M., Nishi K., Ohkubo I.
    Comp. Biochem. Physiol. B, Biochem. Mol. Biol. 146:215-226(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: TestisImported.

Entry informationi

Entry nameiQ4ACT8_PIG
AccessioniPrimary (citable) accession number: Q4ACT8
Entry historyi
Integrated into UniProtKB/TrEMBL: September 13, 2005
Last sequence update: November 8, 2005
Last modified: October 29, 2014
This is version 45 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)