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Q4AAX7

- TRUB_COXBU

UniProt

Q4AAX7 - TRUB_COXBU

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Protein
tRNA pseudouridine synthase B
Gene
truB, CBU_1430
Organism
Coxiella burnetii (strain RSA 493 / Nine Mile phase I)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs By similarity.UniRule annotation

Catalytic activityi

tRNA uridine(55) = tRNA pseudouridine(55).UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei51 – 511Nucleophile By similarity

GO - Molecular functioni

  1. RNA binding Source: InterPro
  2. pseudouridine synthase activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. tRNA pseudouridine synthesis Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

tRNA processing

Enzyme and pathway databases

BioCyciCBUR227377:GJ7S-1417-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA pseudouridine synthase B (EC:5.4.99.25)
Alternative name(s):
tRNA pseudouridine(55) synthase
Short name:
Psi55 synthase
tRNA pseudouridylate synthase
tRNA-uridine isomerase
Gene namesi
Name:truB
Ordered Locus Names:CBU_1430
OrganismiCoxiella burnetii (strain RSA 493 / Nine Mile phase I)
Taxonomic identifieri227377 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaLegionellalesCoxiellaceaeCoxiella
ProteomesiUP000002671: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 309309tRNA pseudouridine synthase BUniRule annotation
PRO_0000229352Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi227377.CBU_1430.

Structurei

3D structure databases

ProteinModelPortaliQ4AAX7.
SMRiQ4AAX7. Positions 13-306.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0130.
HOGENOMiHOG000231223.
KOiK03177.
OMAiYELQFIR.
OrthoDBiEOG6358D3.

Family and domain databases

Gene3Di2.30.130.10. 1 hit.
HAMAPiMF_01080. TruB_bact.
InterProiIPR002501. PsdUridine_synth.
IPR020103. PsdUridine_synth_cat_dom.
IPR015947. PUA-like_domain.
IPR014780. tRNA_psdUridine_synth_TruB.
IPR015240. tRNA_sdUridine_synth_fam1_C.
[Graphical view]
PANTHERiPTHR13767. PTHR13767. 1 hit.
PfamiPF09157. TruB-C_2. 1 hit.
PF01509. TruB_N. 1 hit.
[Graphical view]
SUPFAMiSSF55120. SSF55120. 1 hit.
SSF88697. SSF88697. 1 hit.
TIGRFAMsiTIGR00431. TruB. 1 hit.

Sequencei

Sequence statusi: Complete.

Q4AAX7-1 [UniParc]FASTAAdd to Basket

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MTATNHPKLF KRPVDGVLLL DKPGGMTSNE ALQRVKRLFH AKKAGHTGSL    50
DPLATGLLPI CLGEATKFSQ FLLEADKSYS VKGRLGVRTA SGDSESPILT 100
ERPIPKLTKR ALEKTLFAFR GVIDQTPSMY SALKHKGQPL YKLARQGIEV 150
ERKTRQVTIY ELTLLDWDNE SIELYVHCSK GTYIRTLLDD VGEALGCGAH 200
VVALRRLRVA HYHEDQMIKL AHLEREYDKA NYTGLDRYLL PLETMVSHFP 250
AIKLSSSTAF YLQQGQAVMV PNAPTHGFVR LRDQNDQFIG IGEILSDARI 300
APRRLIQKR 309
Length:309
Mass (Da):34,689
Last modified:September 13, 2005 - v1
Checksum:i2FD72193EDBB13D9
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE016828 Genomic DNA. Translation: AAZ22626.1.
RefSeqiYP_338283.1. NC_002971.3.

Genome annotation databases

EnsemblBacteriaiAAZ22626; AAZ22626; CBU_1430.
GeneIDi1209336.
KEGGicbu:CBU_1430.
PATRICi17931611. VBICoxBur82552_1429.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE016828 Genomic DNA. Translation: AAZ22626.1 .
RefSeqi YP_338283.1. NC_002971.3.

3D structure databases

ProteinModelPortali Q4AAX7.
SMRi Q4AAX7. Positions 13-306.
ModBasei Search...

Protein-protein interaction databases

STRINGi 227377.CBU_1430.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAZ22626 ; AAZ22626 ; CBU_1430 .
GeneIDi 1209336.
KEGGi cbu:CBU_1430.
PATRICi 17931611. VBICoxBur82552_1429.

Phylogenomic databases

eggNOGi COG0130.
HOGENOMi HOG000231223.
KOi K03177.
OMAi YELQFIR.
OrthoDBi EOG6358D3.

Enzyme and pathway databases

BioCyci CBUR227377:GJ7S-1417-MONOMER.

Family and domain databases

Gene3Di 2.30.130.10. 1 hit.
HAMAPi MF_01080. TruB_bact.
InterProi IPR002501. PsdUridine_synth.
IPR020103. PsdUridine_synth_cat_dom.
IPR015947. PUA-like_domain.
IPR014780. tRNA_psdUridine_synth_TruB.
IPR015240. tRNA_sdUridine_synth_fam1_C.
[Graphical view ]
PANTHERi PTHR13767. PTHR13767. 1 hit.
Pfami PF09157. TruB-C_2. 1 hit.
PF01509. TruB_N. 1 hit.
[Graphical view ]
SUPFAMi SSF55120. SSF55120. 1 hit.
SSF88697. SSF88697. 1 hit.
TIGRFAMsi TIGR00431. TruB. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: RSA 493 / Nine Mile phase I.

Entry informationi

Entry nameiTRUB_COXBU
AccessioniPrimary (citable) accession number: Q4AAX7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 4, 2006
Last sequence update: September 13, 2005
Last modified: May 14, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Coxiella burnetii
    Coxiella burnetii (strain RSA 493): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi