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Q4AAX7

- TRUB_COXBU

UniProt

Q4AAX7 - TRUB_COXBU

Protein

tRNA pseudouridine synthase B

Gene

truB

Organism
Coxiella burnetii (strain RSA 493 / Nine Mile phase I)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 53 (01 Oct 2014)
      Sequence version 1 (13 Sep 2005)
      Previous versions | rss
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    Functioni

    Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.UniRule annotation

    Catalytic activityi

    tRNA uridine(55) = tRNA pseudouridine(55).UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei51 – 511NucleophileUniRule annotation

    GO - Molecular functioni

    1. pseudouridine synthase activity Source: UniProtKB-HAMAP
    2. RNA binding Source: InterPro

    GO - Biological processi

    1. tRNA pseudouridine synthesis Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Isomerase

    Keywords - Biological processi

    tRNA processing

    Enzyme and pathway databases

    BioCyciCBUR227377:GJ7S-1417-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    tRNA pseudouridine synthase BUniRule annotation (EC:5.4.99.25UniRule annotation)
    Alternative name(s):
    tRNA pseudouridine(55) synthaseUniRule annotation
    Short name:
    Psi55 synthaseUniRule annotation
    tRNA pseudouridylate synthaseUniRule annotation
    tRNA-uridine isomeraseUniRule annotation
    Gene namesi
    Name:truBUniRule annotation
    Ordered Locus Names:CBU_1430
    OrganismiCoxiella burnetii (strain RSA 493 / Nine Mile phase I)
    Taxonomic identifieri227377 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaLegionellalesCoxiellaceaeCoxiella
    ProteomesiUP000002671: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 309309tRNA pseudouridine synthase BPRO_0000229352Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi227377.CBU_1430.

    Structurei

    3D structure databases

    ProteinModelPortaliQ4AAX7.
    SMRiQ4AAX7. Positions 13-306.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0130.
    HOGENOMiHOG000231223.
    KOiK03177.
    OMAiYELQFIR.
    OrthoDBiEOG6358D3.

    Family and domain databases

    Gene3Di2.30.130.10. 1 hit.
    HAMAPiMF_01080. TruB_bact.
    InterProiIPR002501. PsdUridine_synth.
    IPR020103. PsdUridine_synth_cat_dom.
    IPR015947. PUA-like_domain.
    IPR014780. tRNA_psdUridine_synth_TruB.
    IPR015240. tRNA_sdUridine_synth_fam1_C.
    [Graphical view]
    PANTHERiPTHR13767. PTHR13767. 1 hit.
    PfamiPF09157. TruB-C_2. 1 hit.
    PF01509. TruB_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF55120. SSF55120. 1 hit.
    SSF88697. SSF88697. 1 hit.
    TIGRFAMsiTIGR00431. TruB. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q4AAX7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTATNHPKLF KRPVDGVLLL DKPGGMTSNE ALQRVKRLFH AKKAGHTGSL    50
    DPLATGLLPI CLGEATKFSQ FLLEADKSYS VKGRLGVRTA SGDSESPILT 100
    ERPIPKLTKR ALEKTLFAFR GVIDQTPSMY SALKHKGQPL YKLARQGIEV 150
    ERKTRQVTIY ELTLLDWDNE SIELYVHCSK GTYIRTLLDD VGEALGCGAH 200
    VVALRRLRVA HYHEDQMIKL AHLEREYDKA NYTGLDRYLL PLETMVSHFP 250
    AIKLSSSTAF YLQQGQAVMV PNAPTHGFVR LRDQNDQFIG IGEILSDARI 300
    APRRLIQKR 309
    Length:309
    Mass (Da):34,689
    Last modified:September 13, 2005 - v1
    Checksum:i2FD72193EDBB13D9
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE016828 Genomic DNA. Translation: AAZ22626.1.
    RefSeqiYP_338283.1. NC_002971.3.

    Genome annotation databases

    EnsemblBacteriaiAAZ22626; AAZ22626; CBU_1430.
    GeneIDi1209336.
    KEGGicbu:CBU_1430.
    PATRICi17931611. VBICoxBur82552_1429.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE016828 Genomic DNA. Translation: AAZ22626.1 .
    RefSeqi YP_338283.1. NC_002971.3.

    3D structure databases

    ProteinModelPortali Q4AAX7.
    SMRi Q4AAX7. Positions 13-306.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 227377.CBU_1430.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAZ22626 ; AAZ22626 ; CBU_1430 .
    GeneIDi 1209336.
    KEGGi cbu:CBU_1430.
    PATRICi 17931611. VBICoxBur82552_1429.

    Phylogenomic databases

    eggNOGi COG0130.
    HOGENOMi HOG000231223.
    KOi K03177.
    OMAi YELQFIR.
    OrthoDBi EOG6358D3.

    Enzyme and pathway databases

    BioCyci CBUR227377:GJ7S-1417-MONOMER.

    Family and domain databases

    Gene3Di 2.30.130.10. 1 hit.
    HAMAPi MF_01080. TruB_bact.
    InterProi IPR002501. PsdUridine_synth.
    IPR020103. PsdUridine_synth_cat_dom.
    IPR015947. PUA-like_domain.
    IPR014780. tRNA_psdUridine_synth_TruB.
    IPR015240. tRNA_sdUridine_synth_fam1_C.
    [Graphical view ]
    PANTHERi PTHR13767. PTHR13767. 1 hit.
    Pfami PF09157. TruB-C_2. 1 hit.
    PF01509. TruB_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF55120. SSF55120. 1 hit.
    SSF88697. SSF88697. 1 hit.
    TIGRFAMsi TIGR00431. TruB. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: RSA 493 / Nine Mile phase I.

    Entry informationi

    Entry nameiTRUB_COXBU
    AccessioniPrimary (citable) accession number: Q4AAX7
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 4, 2006
    Last sequence update: September 13, 2005
    Last modified: October 1, 2014
    This is version 53 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Coxiella burnetii
      Coxiella burnetii (strain RSA 493): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3