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Protein

tRNA pseudouridine synthase B

Gene

truB

Organism
Coxiella burnetii (strain RSA 493 / Nine Mile phase I)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.UniRule annotation

Catalytic activityi

tRNA uridine(55) = tRNA pseudouridine(55).UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei51NucleophileUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processtRNA processing

Enzyme and pathway databases

BioCyciCBUR227377:G1G0B-1415-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA pseudouridine synthase BUniRule annotation (EC:5.4.99.25UniRule annotation)
Alternative name(s):
tRNA pseudouridine(55) synthaseUniRule annotation
Short name:
Psi55 synthaseUniRule annotation
tRNA pseudouridylate synthaseUniRule annotation
tRNA-uridine isomeraseUniRule annotation
Gene namesi
Name:truBUniRule annotation
Ordered Locus Names:CBU_1430
OrganismiCoxiella burnetii (strain RSA 493 / Nine Mile phase I)
Taxonomic identifieri227377 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaLegionellalesCoxiellaceaeCoxiella
Proteomesi
  • UP000002671 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002293521 – 309tRNA pseudouridine synthase BAdd BLAST309

Proteomic databases

PRIDEiQ4AAX7

Interactioni

Protein-protein interaction databases

STRINGi227377.CBU_1430

Structurei

3D structure databases

ProteinModelPortaliQ4AAX7
SMRiQ4AAX7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105D0T Bacteria
COG0130 LUCA
HOGENOMiHOG000231223
KOiK03177
OMAiVDCSKGT

Family and domain databases

Gene3Di2.30.130.10, 1 hit
HAMAPiMF_01080 TruB_bact, 1 hit
InterProiView protein in InterPro
IPR020103 PsdUridine_synth_cat_dom_sf
IPR002501 PsdUridine_synth_N
IPR015947 PUA-like_sf
IPR036974 PUA_sf
IPR014780 tRNA_psdUridine_synth_TruB
IPR015240 tRNA_sdUridine_synth_fam1_C
IPR032819 TruB_C
PANTHERiPTHR13767 PTHR13767, 1 hit
PfamiView protein in Pfam
PF09157 TruB-C_2, 1 hit
PF16198 TruB_C_2, 1 hit
PF01509 TruB_N, 1 hit
SUPFAMiSSF55120 SSF55120, 1 hit
SSF88697 SSF88697, 1 hit
TIGRFAMsiTIGR00431 TruB, 1 hit

Sequencei

Sequence statusi: Complete.

Q4AAX7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTATNHPKLF KRPVDGVLLL DKPGGMTSNE ALQRVKRLFH AKKAGHTGSL
60 70 80 90 100
DPLATGLLPI CLGEATKFSQ FLLEADKSYS VKGRLGVRTA SGDSESPILT
110 120 130 140 150
ERPIPKLTKR ALEKTLFAFR GVIDQTPSMY SALKHKGQPL YKLARQGIEV
160 170 180 190 200
ERKTRQVTIY ELTLLDWDNE SIELYVHCSK GTYIRTLLDD VGEALGCGAH
210 220 230 240 250
VVALRRLRVA HYHEDQMIKL AHLEREYDKA NYTGLDRYLL PLETMVSHFP
260 270 280 290 300
AIKLSSSTAF YLQQGQAVMV PNAPTHGFVR LRDQNDQFIG IGEILSDARI

APRRLIQKR
Length:309
Mass (Da):34,689
Last modified:September 13, 2005 - v1
Checksum:i2FD72193EDBB13D9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016828 Genomic DNA Translation: AAZ22626.1
RefSeqiWP_010958222.1, NC_002971.4
YP_338283.1, NC_002971.3

Genome annotation databases

EnsemblBacteriaiAAZ22626; AAZ22626; CBU_1430
GeneIDi1209336
KEGGicbu:CBU_1430
PATRICifig|227377.7.peg.1429

Similar proteinsi

Entry informationi

Entry nameiTRUB_COXBU
AccessioniPrimary (citable) accession number: Q4AAX7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 4, 2006
Last sequence update: September 13, 2005
Last modified: March 28, 2018
This is version 76 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Coxiella burnetii
    Coxiella burnetii (strain RSA 493): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

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