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Q4AAX7 (TRUB_COXBU) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 51. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
tRNA pseudouridine synthase B

EC=5.4.99.25
Alternative name(s):
tRNA pseudouridine(55) synthase
Short name=Psi55 synthase
tRNA pseudouridylate synthase
tRNA-uridine isomerase
Gene names
Name:truB
Ordered Locus Names:CBU_1430
OrganismCoxiella burnetii (strain RSA 493 / Nine Mile phase I) [Reference proteome] [HAMAP]
Taxonomic identifier227377 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaLegionellalesCoxiellaceaeCoxiella

Protein attributes

Sequence length309 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs By similarity. HAMAP-Rule MF_01080

Catalytic activity

tRNA uridine55 = tRNA pseudouridine55. HAMAP-Rule MF_01080

Sequence similarities

Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.

Ontologies

Keywords
   Biological processtRNA processing
   Molecular functionIsomerase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processtRNA pseudouridine synthesis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Molecular_functionRNA binding

Inferred from electronic annotation. Source: InterPro

pseudouridine synthase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 309309tRNA pseudouridine synthase B HAMAP-Rule MF_01080
PRO_0000229352

Sites

Active site511Nucleophile By similarity

Sequences

Sequence LengthMass (Da)Tools
Q4AAX7 [UniParc].

Last modified September 13, 2005. Version 1.
Checksum: 2FD72193EDBB13D9

FASTA30934,689
        10         20         30         40         50         60 
MTATNHPKLF KRPVDGVLLL DKPGGMTSNE ALQRVKRLFH AKKAGHTGSL DPLATGLLPI 

        70         80         90        100        110        120 
CLGEATKFSQ FLLEADKSYS VKGRLGVRTA SGDSESPILT ERPIPKLTKR ALEKTLFAFR 

       130        140        150        160        170        180 
GVIDQTPSMY SALKHKGQPL YKLARQGIEV ERKTRQVTIY ELTLLDWDNE SIELYVHCSK 

       190        200        210        220        230        240 
GTYIRTLLDD VGEALGCGAH VVALRRLRVA HYHEDQMIKL AHLEREYDKA NYTGLDRYLL 

       250        260        270        280        290        300 
PLETMVSHFP AIKLSSSTAF YLQQGQAVMV PNAPTHGFVR LRDQNDQFIG IGEILSDARI 


APRRLIQKR 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE016828 Genomic DNA. Translation: AAZ22626.1.
RefSeqYP_338283.1. NC_002971.3.

3D structure databases

ProteinModelPortalQ4AAX7.
SMRQ4AAX7. Positions 13-306.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING227377.CBU_1430.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAZ22626; AAZ22626; CBU_1430.
GeneID1209336.
KEGGcbu:CBU_1430.
PATRIC17931611. VBICoxBur82552_1429.

Phylogenomic databases

eggNOGCOG0130.
HOGENOMHOG000231223.
KOK03177.
OMAQKVKRIF.
OrthoDBEOG6358D3.
ProtClustDBPRK05033.

Enzyme and pathway databases

BioCycCBUR227377:GJ7S-1417-MONOMER.

Family and domain databases

Gene3D2.30.130.10. 1 hit.
HAMAPMF_01080. TruB_bact.
InterProIPR002501. PsdUridine_synth.
IPR020103. PsdUridine_synth_cat_dom.
IPR015947. PUA-like_domain.
IPR014780. tRNA_psdUridine_synth_TruB.
IPR015240. tRNA_sdUridine_synth_fam1_C.
[Graphical view]
PANTHERPTHR13767. PTHR13767. 1 hit.
PfamPF09157. TruB-C_2. 1 hit.
PF01509. TruB_N. 1 hit.
[Graphical view]
SUPFAMSSF55120. SSF55120. 1 hit.
SSF88697. SSF88697. 1 hit.
TIGRFAMsTIGR00431. TruB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameTRUB_COXBU
AccessionPrimary (citable) accession number: Q4AAX7
Entry history
Integrated into UniProtKB/Swiss-Prot: April 4, 2006
Last sequence update: September 13, 2005
Last modified: February 19, 2014
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Coxiella burnetii

Coxiella burnetii (strain RSA 493): entries and gene names