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Protein

Peptidyl-tRNA hydrolase

Gene

pth

Organism
Mycoplasma hyopneumoniae (strain J / ATCC 25934 / NCTC 10110)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.UniRule annotation

Catalytic activityi

N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Peptidyl-tRNA hydrolaseUniRule annotation (EC:3.1.1.29UniRule annotation)
Short name:
PTHUniRule annotation
Gene namesi
Name:pthUniRule annotation
Ordered Locus Names:MHJ_0200
OrganismiMycoplasma hyopneumoniae (strain J / ATCC 25934 / NCTC 10110)
Taxonomic identifieri262719 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
Proteomesi
  • UP000000548 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002640621 – 184Peptidyl-tRNA hydrolaseAdd BLAST184

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi262719.MHJ_0200

Structurei

3D structure databases

ProteinModelPortaliQ4AAD0
SMRiQ4AAD0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PTH family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108ZPD Bacteria
COG0193 LUCA
HOGENOMiHOG000004797
KOiK01056
OMAiRYAHTRH

Family and domain databases

CDDicd00462 PTH, 1 hit
Gene3Di3.40.50.1470, 1 hit
HAMAPiMF_00083 Pept_tRNA_hydro_bact, 1 hit
InterProiView protein in InterPro
IPR001328 Pept_tRNA_hydro
IPR018171 Pept_tRNA_hydro_CS
IPR036416 Pept_tRNA_hydro_sf
PANTHERiPTHR17224 PTHR17224, 1 hit
PfamiView protein in Pfam
PF01195 Pept_tRNA_hydro, 1 hit
SUPFAMiSSF53178 SSF53178, 1 hit
TIGRFAMsiTIGR00447 pth, 1 hit
PROSITEiView protein in PROSITE
PS01195 PEPT_TRNA_HYDROL_1, 1 hit

Sequencei

Sequence statusi: Complete.

Q4AAD0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLIVGLGNP GEKYAKTKHN VGYWVLDLLA EKLALSFDQK TENGIYVKQP
60 70 80 90 100
DFILAKPTTF MNKSGDFVEE LIKFYKINTQ DLMIIYDDMN FEVGQAAIKT
110 120 130 140 150
TGSAGGQRGM AHIIEKCKTK EIKRLKIGIS RGENAKEYVL SPFLPKDNAK
160 170 180
IKLVIEEAAN ILIFYLSNSF ITTIEKFNAN KNKV
Length:184
Mass (Da):20,744
Last modified:September 13, 2005 - v1
Checksum:iF15DF149180385C1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017243 Genomic DNA Translation: AAZ44291.1
RefSeqiWP_011206014.1, NC_007295.1

Genome annotation databases

EnsemblBacteriaiAAZ44291; AAZ44291; MHJ_0200
KEGGimhj:MHJ_0200

Similar proteinsi

Entry informationi

Entry nameiPTH_MYCHJ
AccessioniPrimary (citable) accession number: Q4AAD0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: September 13, 2005
Last modified: March 28, 2018
This is version 75 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health