Q4A8E0 (Q4A8E0_MYCH7) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Methylmalonate-semialdehyde dehydrogenase EMBL AAZ53599.1
EC=1.2.1.27 EMBL AAZ53599.1

Gene names

Ordered Locus Names:

MHP7448_0225

Organism

Mycoplasma hyopneumoniae (strain 7448) [Complete proteome] [HAMAP]

Taxonomic identifier

262722 [NCBI]

Taxonomic lineage

Bacteria › Tenericutes › Mollicutes › Mycoplasmataceae › Mycoplasma

Protein attributes

Sequence length	489 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the aldehyde dehydrogenase family. RuleBase RU003345

Ontologies

Keywords
Molecular function	Oxidoreductase RuleBase RU003344 EMBL AAZ53599.1
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	methylmalonate-semialdehyde dehydrogenase (acylating) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q4A8E0 [UniParc]. Last modified September 13, 2005. Version 1. Checksum: 175AF5CDA49669EC	FASTA	489	53,859
	10 20 30 40 50 60 MNFKRNYIQS FYANEFHSEE NPKTLDIFSP HDGSVLAKLE ITSTSTLDKI VAQAKTAQEK 70 80 90 100 110 120 WASLTFKKRS EVIYKYRELV IRYKQELAHL IHIDNGKTLK EAVAEVEKVV ELTEFACSIP 130 140 150 160 170 180 QLVSGETQMV SRGIIAREER RPVGVFGIIA PFNFPLMVPN WSIPNAIALG NAVILKGSEL 190 200 210 220 230 240 CGLSASFMAD LWKQAGLPSG IFNLVNGQAE IANAMINHPE IDGITFVGST EIAKLVHKNA 250 260 270 280 290 300 SNLNKRVLAL GGAKNHIFVL KDAPIETASS EVLAAALGMA GQRCMAASVA LVVGQNEEFI 310 320 330 340 350 360 QALIEKARKF KLDFDLPPLV SKASVDKLVT YLNWAKEQGA KILVNGITDF LIPENKKEGF 370 380 390 400 410 420 WFGPTIIDWS EIPEKMGSQE VFGPILEIIR TKNLSEAIKI QQKSPYGNAA SVYTQSGRAA 430 440 450 460 470 480 EEIIAKVKPG MLGVNIGVPV PREPFSFGGT RSSKFGYGDI TGKSSINFWT NLIKVTTKWN PEDKQDWMS

References

[1]

"Swine and poultry pathogens: the complete genome sequences of two strains of Mycoplasma hyopneumoniae and a strain of Mycoplasma synoviae." Vasconcelos A.T.R., Ferreira H.B., Bizarro C.V., Bonatto S.L., Carvalho M.O., Pinto P.M., Almeida D.F., Almeida L.G.P., Almeida R., Alves-Junior L., Assuncao E.N., Azevedo V.A.C., Bogo M.R., Brigido M.M., Brocchi M., Burity H.A., Camargo A.A., Camargo S.S. , Carepo M.S., Carraro D.M., de Mattos Cascardo J.C., Castro L.A., Cavalcanti G., Chemale G., Collevatti R.G., Cunha C.W., Dallagiovanna B., Dambros B.P., Dellagostin O.A., Falcao C., Fantinatti-Garboggini F., Felipe M.S.S., Fiorentin L., Franco G.R., Freitas N.S.A., Frias D., Grangeiro T.B., Grisard E.C., Guimaraes C.T., Hungria M., Jardim S.N., Krieger M.A., Laurino J.P., Lima L.F.A., Lopes M.I., Loreto E.L.S., Madeira H.M.F., Manfio G.P., Maranhao A.Q., Martinkovics C.T., Medeiros S.R.B., Moreira M.A.M., Neiva M., Ramalho-Neto C.E., Nicolas M.F., Oliveira S.C., Paixao R.F.C., Pedrosa F.O., Pena S.D.J., Pereira M., Pereira-Ferrari L., Piffer I., Pinto L.S., Potrich D.P., Salim A.C.M., Santos F.R., Schmitt R., Schneider M.P.C., Schrank A., Schrank I.S., Schuck A.F., Seuanez H.N., Silva D.W., Silva R., Silva S.C., Soares C.M.A., Souza K.R.L., Souza R.C., Staats C.C., Steffens M.B.R., Teixeira S.M.R., Urmenyi T.P., Vainstein M.H., Zuccherato L.W., Simpson A.J.G., Zaha A. J. Bacteriol. 187:5568-5577(2005) [PubMed: 16077101] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE017244 Genomic DNA. Translation: AAZ53599.1.
RefSeq	YP_287622.1. NC_007332.1.
3D structure databases
ProteinModelPortal	Q4A8E0.
ModBase	Search...
Protein-protein interaction databases
STRING	Q4A8E0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3570478.
GenomeReviews	Gene locus MHP7448_0225 in contig AE017244_GR.
KEGG	mhp:MHP7448_0225.
PATRIC	20012632. VBIMycHyo9249_0254.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1012.
HOGENOM	HBG752218.
OMA	IANAMIN.
PhylomeDB	Q4A8E0.
ProtClustDB	CLSK741473.
Family and domain databases
InterPro	IPR016161. Ald_DH/histidinol_DH. IPR016163. Ald_DH_C. IPR016160. Ald_DH_CS. IPR016162. Ald_DH_N. IPR015590. Aldehyde_DH_dom. IPR010061. MeMal-semiAld_DH. [Graphical view]
Gene3D	G3DSA:3.40.309.10. Aldehyde_dehydrogenase_C. 1 hit. G3DSA:3.40.605.10. Aldehyde_dehydrogenase_N. 1 hit.
KO	K00140.
PANTHER	PTHR11699:SF27. MMSDH. 1 hit.
Pfam	PF00171. Aldedh. 1 hit. [Graphical view]
SUPFAM	SSF53720. Aldehyde_DH/Histidinol_DH. 1 hit.
PROSITE	PS00070. ALDEHYDE_DEHYDR_CYS. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q4A8E0_MYCH7

Accession

Primary (citable) accession number: Q4A8E0

Entry history

Integrated into UniProtKB/TrEMBL:	September 13, 2005
Last sequence update:	September 13, 2005
Last modified:	December 14, 2011
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)