ID   Q4A6S8_MYCS5            Unreviewed;       248 AA.
AC   Q4A6S8;
DT   13-SEP-2005, integrated into UniProtKB/TrEMBL.
DT   13-SEP-2005, sequence version 1.
DT   27-MAR-2024, entry version 93.
DE   RecName: Full=protein-serine/threonine phosphatase {ECO:0000256|ARBA:ARBA00013081};
DE            EC=3.1.3.16 {ECO:0000256|ARBA:ARBA00013081};
GN   Name=prpC {ECO:0000313|EMBL:AAZ43543.1};
GN   OrderedLocusNames=MS53_0122 {ECO:0000313|EMBL:AAZ43543.1};
OS   Mycoplasmopsis synoviae (strain 53) (Mycoplasma synoviae).
OC   Bacteria; Mycoplasmatota; Mycoplasmoidales; Metamycoplasmataceae;
OC   Mycoplasmopsis.
OX   NCBI_TaxID=262723 {ECO:0000313|EMBL:AAZ43543.1, ECO:0000313|Proteomes:UP000000549};
RN   [1] {ECO:0000313|EMBL:AAZ43543.1, ECO:0000313|Proteomes:UP000000549}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=53 {ECO:0000313|EMBL:AAZ43543.1,
RC   ECO:0000313|Proteomes:UP000000549};
RX   PubMed=16077101; DOI=10.1128/JB.187.16.5568-5577.2005;
RA   Vasconcelos A.T., Ferreira H.B., Bizarro C.V., Bonatto S.L., Carvalho M.O.,
RA   Pinto P.M., Almeida D.F., Almeida L.G., Almeida R., Alves-Filho L.,
RA   Assuncao E.N., Azevedo V.A., Bogo M.R., Brigido M.M., Brocchi M.,
RA   Burity H.A., Camargo A.A., Camargo S.S., Carepo M.S., Carraro D.M.,
RA   de Mattos Cascardo J.C., Castro L.A., Cavalcanti G., Chemale G.,
RA   Collevatti R.G., Cunha C.W., Dallagiovanna B., Dambros B.P.,
RA   Dellagostin O.A., Falcao C., Fantinatti-Garboggini F., Felipe M.S.,
RA   Fiorentin L., Franco G.R., Freitas N.S., Frias D., Grangeiro T.B.,
RA   Grisard E.C., Guimaraes C.T., Hungria M., Jardim S.N., Krieger M.A.,
RA   Laurino J.P., Lima L.F., Lopes M.I., Loreto E.L., Madeira H.M.,
RA   Manfio G.P., Maranhao A.Q., Martinkovics C.T., Medeiros S.R., Moreira M.A.,
RA   Neiva M., Ramalho-Neto C.E., Nicolas M.F., Oliveira S.C., Paixao R.F.,
RA   Pedrosa F.O., Pena S.D., Pereira M., Pereira-Ferrari L., Piffer I.,
RA   Pinto L.S., Potrich D.P., Salim A.C., Santos F.R., Schmitt R.,
RA   Schneider M.P., Schrank A., Schrank I.S., Schuck A.F., Seuanez H.N.,
RA   Silva D.W., Silva R., Silva S.C., Soares C.M., Souza K.R., Souza R.C.,
RA   Staats C.C., Steffens M.B., Teixeira S.M., Urmenyi T.P., Vainstein M.H.,
RA   Zuccherato L.W., Simpson A.J., Zaha A.;
RT   "Swine and poultry pathogens: the complete genome sequences of two strains
RT   of Mycoplasma hyopneumoniae and a strain of Mycoplasma synoviae.";
RL   J. Bacteriol. 187:5568-5577(2005).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H2O + O-phospho-L-seryl-[protein] = L-seryl-[protein] +
CC         phosphate; Xref=Rhea:RHEA:20629, Rhea:RHEA-COMP:9863, Rhea:RHEA-
CC         COMP:11604, ChEBI:CHEBI:15377, ChEBI:CHEBI:29999, ChEBI:CHEBI:43474,
CC         ChEBI:CHEBI:83421; EC=3.1.3.16;
CC         Evidence={ECO:0000256|ARBA:ARBA00001512};
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] +
CC         phosphate; Xref=Rhea:RHEA:47004, Rhea:RHEA-COMP:11060, Rhea:RHEA-
CC         COMP:11605, ChEBI:CHEBI:15377, ChEBI:CHEBI:30013, ChEBI:CHEBI:43474,
CC         ChEBI:CHEBI:61977; EC=3.1.3.16;
CC         Evidence={ECO:0000256|ARBA:ARBA00001482};
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DR   EMBL; AE017245; AAZ43543.1; -; Genomic_DNA.
DR   RefSeq; WP_011283286.1; NC_007294.1.
DR   AlphaFoldDB; Q4A6S8; -.
DR   STRING; 262723.MS53_0122; -.
DR   KEGG; msy:MS53_0122; -.
DR   eggNOG; COG0631; Bacteria.
DR   HOGENOM; CLU_034545_4_1_14; -.
DR   OrthoDB; 9801841at2; -.
DR   BRENDA; 3.1.3.16; 10311.
DR   Proteomes; UP000000549; Chromosome.
DR   GO; GO:0017018; F:myosin phosphatase activity; IEA:UniProtKB-EC.
DR   CDD; cd00143; PP2Cc; 1.
DR   Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR   InterPro; IPR015655; PP2C.
DR   InterPro; IPR036457; PPM-type-like_dom_sf.
DR   InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR   PANTHER; PTHR47992:SF267; ALPHABET, ISOFORM E; 1.
DR   PANTHER; PTHR47992; PROTEIN PHOSPHATASE; 1.
DR   Pfam; PF13672; PP2C_2; 1.
DR   SMART; SM00331; PP2C_SIG; 1.
DR   SMART; SM00332; PP2Cc; 1.
DR   SUPFAM; SSF81606; PP2C-like; 1.
DR   PROSITE; PS51746; PPM_2; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000313|EMBL:AAZ43543.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000549}.
FT   DOMAIN          1..246
FT                   /note="PPM-type phosphatase"
FT                   /evidence="ECO:0000259|PROSITE:PS51746"
SQ   SEQUENCE   248 AA;  28004 MW;  3B980233BE3F5066 CRC64;
     MISLKSISIT GAYRKKNDDR VSHFENDDFL VALVCDGMGG HLHGDIAAEE TAKIFTNQFS
     KNFSYISFQE TSLWLKNVVN LVKKRFKDLI KSDFSKERMG TTLTGVLILK KIQKIIVFHI
     GDSRCYFYTK EKKLVQITQD HSYENKLLSA GISLEEAKSN PKGRLLTSVL SLKNKITFNI
     YDLDQIDYAK VDKIILTSDG AHEFISSEEF KAELKSSSSE KIVNSLVEIA QKNDSTDNIS
     CIVIKLGE
//