Q4A6D1 (Q4A6D1_MYCS5) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Excinuclease ABC subunit C EMBL AAZ43690.1

Gene names

Name:	uvrC EMBL AAZ43690.1
Ordered Locus Names:	MS53_0271

Organism

Mycoplasma synoviae (strain 53) [Complete proteome] [HAMAP] EMBL AAZ43690.1

Taxonomic identifier

262723 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Tenericutes › Mollicutes › Mycoplasmatales › Mycoplasmataceae › Mycoplasma › Mycoplasma synoviae

Protein attributes

Sequence length	582 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision By similarity. SAAS SAAS001162
Subunit structure	Interacts with UvrB in an incision complex By similarity. SAAS SAAS001162
Subcellular location	Cytoplasm By similarity SAAS SAAS001162.
Sequence similarities	Contains 1 GIY-YIG domain. SAAS SAAS001162 Contains 1 UVR domain. SAAS SAAS001162

Ontologies

Keywords
Biological process	DNA damage DNA excision SAAS SAAS001162 DNA repair SOS response SAAS SAAS001162
Cellular component	Cytoplasm SAAS SAAS001162
Molecular function	Excision nuclease SAAS SAAS001162
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	DNA repair Inferred from electronic annotation. Source: UniProtKB-KW SOS response Inferred from electronic annotation. Source: UniProtKB-KW nucleic acid phosphodiester bond hydrolysis Inferred from electronic annotation. Source: GOC
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	DNA binding Inferred from electronic annotation. Source: InterPro nuclease activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q4A6D1 [UniParc]. Last modified September 13, 2005. Version 1. Checksum: 546982D90CB3FF93	FASTA	582	69,318
	10 20 30 40 50 60 MDKKQELLSL LKNIPKKPGT YLWKDQFDNV IYVGKANNLH NRMNSYFKGN INSFKTYAMF 70 80 90 100 110 120 ENIYSFDYFI ADSPKAALIL EKKYIDQYRP KYNIMLLDDK QYPYLNIKIK DSLEIKQTYR 130 140 150 160 170 180 VSKNSEFNIY YGPYPQSHLF KFVKILQRIF LYNQGLLIKD KPKMYWIEKF NILKEILKFK 190 200 210 220 230 240 NNDFNNLLKE KMIAAADNLN FEAAIEYQKA LEFISQFKEK QIIEISKYKN YDVFSFEEKN 250 260 270 280 290 300 ESIAIFYMLY IYGVQNIFQR KIIENYDSLE NIISNFLKEF YKNKALPDNI ILDYKYKDLN 310 320 330 340 350 360 LDLDFKSKII FPQKGINHDL IKLANENNNS GYESYLNQKI ILEQHKLNLW KNLASELFLD 370 380 390 400 410 420 KLNSIFIFDN SHFNNSNPIG SCICYTKAEK NPHLYASFNH EKEQKELKIK SDIEYMYHSV 430 440 450 460 470 480 YKYLKRNHLF ITKDDIFILD GSSMQIKFAQ KAILDFNKDF NANLEIKLFG LVKDKNHKTN 490 500 510 520 530 540 LMINSKDEII KISSESFLFL SKIQEEVDLF AKKRMQKNQI NLTFKSRLIQ IKGISYKTEE 550 560 570 580 KLLKHFGTFA NIYNASFEEL QKVTNKSIAQ KIKENLDIIA RK

References

[1]

"Swine and poultry pathogens: the complete genome sequences of two strains of Mycoplasma hyopneumoniae and a strain of Mycoplasma synoviae." Vasconcelos A.T.R., Ferreira H.B., Bizarro C.V., Bonatto S.L., Carvalho M.O., Pinto P.M., Almeida D.F., Almeida L.G.P., Almeida R., Alves-Junior L., Assuncao E.N., Azevedo V.A.C., Bogo M.R., Brigido M.M., Brocchi M., Burity H.A., Camargo A.A., Camargo S.S. , Carepo M.S., Carraro D.M., de Mattos Cascardo J.C., Castro L.A., Cavalcanti G., Chemale G., Collevatti R.G., Cunha C.W., Dallagiovanna B., Dambros B.P., Dellagostin O.A., Falcao C., Fantinatti-Garboggini F., Felipe M.S.S., Fiorentin L., Franco G.R., Freitas N.S.A., Frias D., Grangeiro T.B., Grisard E.C., Guimaraes C.T., Hungria M., Jardim S.N., Krieger M.A., Laurino J.P., Lima L.F.A., Lopes M.I., Loreto E.L.S., Madeira H.M.F., Manfio G.P., Maranhao A.Q., Martinkovics C.T., Medeiros S.R.B., Moreira M.A.M., Neiva M., Ramalho-Neto C.E., Nicolas M.F., Oliveira S.C., Paixao R.F.C., Pedrosa F.O., Pena S.D.J., Pereira M., Pereira-Ferrari L., Piffer I., Pinto L.S., Potrich D.P., Salim A.C.M., Santos F.R., Schmitt R., Schneider M.P.C., Schrank A., Schrank I.S., Schuck A.F., Seuanez H.N., Silva D.W., Silva R., Silva S.C., Soares C.M.A., Souza K.R.L., Souza R.C., Staats C.C., Steffens M.B.R., Teixeira S.M.R., Urmenyi T.P., Vainstein M.H., Zuccherato L.W., Simpson A.J.G., Zaha A. J. Bacteriol. 187:5568-5577(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 53.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE017245 Genomic DNA. Translation: AAZ43690.1.
RefSeq	YP_278401.1. NC_007294.1.
3D structure databases
ProteinModelPortal	Q4A6D1.
ModBase	Search...
Protein-protein interaction databases
STRING	262723.MS53_0271.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAZ43690; AAZ43690; MS53_0271.
GeneID	3564397.
KEGG	msy:MS53_0271.
PATRIC	20025122. VBIMycSyn118523_0288.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0322.
HOGENOM	HOG000279960.
KO	K03703.
OMA	DNSHIAN.
ProtClustDB	CLSK799443.
Enzyme and pathway databases
BioCyc	MSYN262723:GH37-278-MONOMER.
Family and domain databases
Gene3D	3.40.1440.10. 1 hit.
InterPro	IPR027299. GIY-YIG_dom. IPR000305. GIY-YIG_SF. IPR003583. Hlx-hairpin-Hlx_DNA-bd_motif. IPR010994. RuvA_2-like. IPR001943. UVR_dom. IPR001162. UvrC_homol_region. [Graphical view]
Pfam	PF01541. GIY-YIG. 1 hit. PF08459. UvrC_HhH_N. 1 hit. [Graphical view]
SMART	SM00465. GIYc. 1 hit. SM00278. HhH1. 1 hit. [Graphical view]
SUPFAM	SSF47781. RuvA_2_like. 1 hit. SSF46600. UvrB_C. 1 hit. SSF82771. UvrC_N. 1 hit.
PROSITE	PS50164. GIY_YIG. 1 hit. PS50165. UVRC. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q4A6D1_MYCS5

Accession

Primary (citable) accession number: Q4A6D1

Entry history

Integrated into UniProtKB/TrEMBL:	September 13, 2005
Last sequence update:	September 13, 2005
Last modified:	May 29, 2013
This is version 65 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)