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Q4A5P2 (Q4A5P2_MYCS5) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 43. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Thymidine kinase RuleBase RU000544 HAMAP MF_00124
EC=2.7.1.21 RuleBase RU000544 HAMAP MF_00124
Gene names
Name:tdk HAMAP MF_00124 EMBL AAZ43929.1
Ordered Locus Names:MS53_0521
OrganismMycoplasma synoviae (strain 53) [Complete proteome] [HAMAP]
Taxonomic identifier262723 [NCBI]
Taxonomic lineageBacteria › Tenericutes › Mollicutes › Mycoplasmataceae › Mycoplasma

Protein attributes

Sequence length183 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + thymidine = ADP + thymidine 5'-phosphate. RuleBase RU000544 SAAS SAAS020634 HAMAP MF_00124

Subunit structure

Homotetramer By similarity. HAMAP MF_00124

Subcellular location

Cytoplasm By similarity HAMAP MF_00124.

Sequence similarities

Belongs to the thymidine kinase family. RuleBase RU004165 HAMAP MF_00124

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding15 – 228ATP By similarity HAMAP MF_00124
Nucleotide binding88 – 914ATP By similarity HAMAP MF_00124

Sites

Active site891Proton acceptor By similarity HAMAP MF_00124
Metal binding1451Zinc By similarity HAMAP MF_00124
Metal binding1481Zinc By similarity HAMAP MF_00124
Metal binding1761Zinc By similarity HAMAP MF_00124
Metal binding1791Zinc By similarity HAMAP MF_00124

Sequences

Sequence LengthMass (Da)Tools
Q4A5P2 [UniParc].

Last modified September 13, 2005. Version 1.
Checksum: CA97CF80A439C64E

FASTA18321,146
        10         20         30         40         50         60 
MRWKYDIGSL EVITGPMFAG KSNEIIRILN VNQIAGFKPL SFKPDFDTRW SVNHIVSRTG 

        70         80         90        100        110        120 
SKMETINLKD PKDIWNHIKK DTQVIAFDEV HFFDMSIVAE IQKLIEKKYK VIVSGLDMDY 

       130        140        150        160        170        180 
LGKPFEVVSQ LCCLADKIKK LKAVCMNCHG VANMTYRKVD NNERNLLGDS EYEARCRNCH 


KLR

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References

[1]"Swine and poultry pathogens: the complete genome sequences of two strains of Mycoplasma hyopneumoniae and a strain of Mycoplasma synoviae."
Vasconcelos A.T.R., Ferreira H.B., Bizarro C.V., Bonatto S.L., Carvalho M.O., Pinto P.M., Almeida D.F., Almeida L.G.P., Almeida R., Alves-Junior L., Assuncao E.N., Azevedo V.A.C., Bogo M.R., Brigido M.M., Brocchi M., Burity H.A., Camargo A.A., Camargo S.S. expand/collapse author list , Carepo M.S., Carraro D.M., de Mattos Cascardo J.C., Castro L.A., Cavalcanti G., Chemale G., Collevatti R.G., Cunha C.W., Dallagiovanna B., Dambros B.P., Dellagostin O.A., Falcao C., Fantinatti-Garboggini F., Felipe M.S.S., Fiorentin L., Franco G.R., Freitas N.S.A., Frias D., Grangeiro T.B., Grisard E.C., Guimaraes C.T., Hungria M., Jardim S.N., Krieger M.A., Laurino J.P., Lima L.F.A., Lopes M.I., Loreto E.L.S., Madeira H.M.F., Manfio G.P., Maranhao A.Q., Martinkovics C.T., Medeiros S.R.B., Moreira M.A.M., Neiva M., Ramalho-Neto C.E., Nicolas M.F., Oliveira S.C., Paixao R.F.C., Pedrosa F.O., Pena S.D.J., Pereira M., Pereira-Ferrari L., Piffer I., Pinto L.S., Potrich D.P., Salim A.C.M., Santos F.R., Schmitt R., Schneider M.P.C., Schrank A., Schrank I.S., Schuck A.F., Seuanez H.N., Silva D.W., Silva R., Silva S.C., Soares C.M.A., Souza K.R.L., Souza R.C., Staats C.C., Steffens M.B.R., Teixeira S.M.R., Urmenyi T.P., Vainstein M.H., Zuccherato L.W., Simpson A.J.G., Zaha A.
J. Bacteriol. 187:5568-5577(2005) [PubMed: 16077101] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE017245 Genomic DNA. Translation: AAZ43929.1.
RefSeqYP_278640.1. NC_007294.1.

3D structure databases

ProteinModelPortalQ4A5P2.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ4A5P2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3564556.
GenomeReviewsGene locus MS53_0521 in contig AE017245_GR.
KEGGmsy:MS53_0521.
PATRIC20025684. VBIMycSyn118523_0557.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1435.
HOGENOMHBG522108.
OMAEPRCRHH.
PhylomeDBQ4A5P2.

Family and domain databases

HAMAPMF_00124. Thymidine_kinase.
[Tree]
InterProIPR001267. Thymidine_kinase.
IPR020634. Thymidine_kinase_subgr.
[Graphical view]
KOK00857.
PANTHERPTHR11441. TK_cell. 1 hit.
PfamPF00265. TK. 1 hit.
[Graphical view]
PIRSFPIRSF035805. TK_cell. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ4A5P2_MYCS5
AccessionPrimary (citable) accession number: Q4A5P2
Entry history
Integrated into UniProtKB/TrEMBL: September 13, 2005
Last sequence update: September 13, 2005
Last modified: December 14, 2011
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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