ID   NANE_STAS1              Reviewed;         222 AA.
AC   Q4A094;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   13-SEP-2005, sequence version 1.
DT   16-JUN-2009, entry version 26.
DE   RecName: Full=Putative N-acetylmannosamine-6-phosphate 2-epimerase;
DE            EC=5.1.3.9;
DE   AltName: Full=ManNAc-6-P epimerase;
GN   Name=nanE; OrderedLocusNames=SSP0372;
OS   Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 /
OS   DSM 20229).
OC   Bacteria; Firmicutes; Bacillales; Staphylococcus.
OX   NCBI_TaxID=342451;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16135568; DOI=10.1073/pnas.0502950102;
RA   Kuroda M., Yamashita A., Hirakawa H., Kumano M., Morikawa K.,
RA   Higashide M., Maruyama A., Inose Y., Matoba K., Toh H., Kuhara S.,
RA   Hattori M., Ohta T.;
RT   "Whole genome sequence of Staphylococcus saprophyticus reveals the
RT   pathogenesis of uncomplicated urinary tract infection.";
RL   Proc. Natl. Acad. Sci. U.S.A. 102:13272-13277(2005).
CC   -!- FUNCTION: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to
CC       N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (Potential).
CC   -!- CATALYTIC ACTIVITY: N-acyl-D-glucosamine 6-phosphate = N-acyl-D-
CC       mannosamine 6-phosphate.
CC   -!- PATHWAY: Amino-sugar metabolism; N-acetylneuraminic acid
CC       degradation; D-fructose 6-phosphate from N-acetylneuraminic acid:
CC       step 3/5.
CC   -!- SIMILARITY: Belongs to the nanE family.
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DR   EMBL; AP008934; BAE17517.1; -; Genomic_DNA.
DR   RefSeq; YP_300462.1; -.
DR   SMR; Q4A094; 1-221.
DR   GeneID; 3617192; -.
DR   GenomeReviews; AP008934_GR; SSP0372.
DR   KEGG; ssp:SSP0372; -.
DR   NMPDR; fig|342451.4.peg.230; -.
DR   HOGENOM; Q4A094; -.
DR   OMA; Q4A094; YNTPELA.
DR   BioCyc; SSAP342451:SSP0372-MON; -.
DR   GO; GO:0047465; F:N-acylglucosamine-6-phosphate 2-epimerase a...; IEA:EC.
DR   GO; GO:0006051; P:N-acetylmannosamine metabolic process; IEA:HAMAP.
DR   HAMAP; MF_01235; -; 1.
DR   InterPro; IPR007260; NanE.
DR   Pfam; PF04131; NanE; 1.
PE   3: Inferred from homology;
KW   Carbohydrate metabolism; Complete proteome; Isomerase.
FT   CHAIN         1    222       Putative N-acetylmannosamine-6-phosphate
FT                                2-epimerase.
FT                                /FTId=PRO_0000301488.
SQ   SEQUENCE   222 AA;  24438 MW;  1C2906F73EA8FC5F CRC64;
     MLPQGLIVSC QALPDEPLHS SFIMSKMALA AYEGGAVGIR ANSKADIIEI KKEVDLPVIG
     IVKRDYAHSD VFITATSKEI DELIESNCEV IALDATKQTR PKESLSELVS YIRNKAPNVE
     IMADISTLEE AKNADELGFD YVGTTLRGYT SYTKGHILYE NNYQFLKDVL AHVNAKVIAE
     GNVITPEMFK DVTDLGVHCT VVGGAITRPK EITKRFINAF DK
//