Skip Header

 
Contribute Send feedback
Read comments (0) or add your own

Reviewed, UniProtKB/Swiss-Prot Q4A094 (NANE_STAS1)

Last modified June 16, 2009. Version 26. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Putative N-acetylmannosamine-6-phosphate 2-epimerase
    EC=5.1.3.9
Alternative name(s):
    ManNAc-6-P epimerase
Gene names
Name: nanE
Ordered Locus Names: SSP0372
OrganismStaphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229) [Complete proteome] [HAMAP]
Taxonomic identifier342451 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacillalesStaphylococcus

Protein attributes

Sequence length222 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

General annotation (Comments)

Function

Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) Potential.

Catalytic activity

N-acyl-D-glucosamine 6-phosphate = N-acyl-D-mannosamine 6-phosphate. HAMAP MF_01235

Pathway

Amino-sugar metabolism; N-acetylneuraminic acid degradation; D-fructose 6-phosphate from N-acetylneuraminic acid: step 3/5. HAMAP MF_01235

Sequence similarities

Belongs to the nanE family.

Ontologies

Keywords
   Biological processCarbohydrate metabolism
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processN-acetylmannosamine metabolic process

Inferred from electronic annotation. Source: HAMAP

   Molecular functionN-acylglucosamine-6-phosphate 2-epimerase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 222222Putative N-acetylmannosamine-6-phosphate 2-epimerase HAMAP MF_01235
PRO_0000301488

Sequences

Sequence LengthMass (Da)Tools
Q4A094-1 [UniParc].

Last modified September 13, 2005. Version 1.
Checksum: 1C2906F73EA8FC5F

FASTA22224,438
        10         20         30         40         50         60 
MLPQGLIVSC QALPDEPLHS SFIMSKMALA AYEGGAVGIR ANSKADIIEI KKEVDLPVIG 

        70         80         90        100        110        120 
IVKRDYAHSD VFITATSKEI DELIESNCEV IALDATKQTR PKESLSELVS YIRNKAPNVE 

       130        140        150        160        170        180 
IMADISTLEE AKNADELGFD YVGTTLRGYT SYTKGHILYE NNYQFLKDVL AHVNAKVIAE 

       190        200        210        220 
GNVITPEMFK DVTDLGVHCT VVGGAITRPK EITKRFINAF DK 

« Hide

References

[1]"Whole genome sequence of Staphylococcus saprophyticus reveals the pathogenesis of uncomplicated urinary tract infection."
Kuroda M., Yamashita A., Hirakawa H., Kumano M., Morikawa K., Higashide M., Maruyama A., Inose Y., Matoba K., Toh H., Kuhara S., Hattori M., Ohta T.
Proc. Natl. Acad. Sci. U.S.A. 102:13272-13277(2005) [PubMed: 16135568] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

AP008934 Genomic DNA. Translation: BAE17517.1.
RefSeqYP_300462.1.

3D structure databases

SMRQ4A094. Positions 1-221.
ModBaseSearch...

Genome annotation databases

GeneID3617192.
GenomeReviewsGene locus SSP0372 in contig AP008934_GR.
KEGGssp:SSP0372.
NMPDRfig|342451.4.peg.230.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMQ4A094.
OMAQ4A094. YNTPELA.

Enzyme and pathway databases

BioCycSSAP342451:SSP0372-MON.

Family and domain databases

HAMAPMF_01235.
[Tree]
InterProIPR007260. NanE.
[Graphical view]
PfamPF04131. NanE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameNANE_STAS1
AccessionPrimary (citable) accession number: Q4A094
Entry history
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: September 13, 2005
Last modified: June 16, 2009
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents