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Q4A041 (SDHD_STAS1) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 39. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable D-serine dehydratase
EC=4.3.1.18
Alternative name(s):
D-serine deaminase
Short name=DSD
Gene names
Name:dsdA
Ordered Locus Names:SSP0432
OrganismStaphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229) [Complete proteome] [HAMAP]
Taxonomic identifier342451 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Staphylococcus

Protein attributes

Sequence length433 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-serine = pyruvate + NH3. HAMAP MF_01030

Cofactor

Pyridoxal phosphate By similarity. HAMAP MF_01030

Sequence similarities

Belongs to the serine/threonine dehydratase family. DsdA subfamily.

Ontologies

Keywords
   LigandPyridoxal phosphate
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processD-amino acid metabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular functionD-serine ammonia-lyase activity

Inferred from electronic annotation. Source: EC

pyridoxal phosphate binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 433433Probable D-serine dehydratase HAMAP MF_01030
PRO_0000291745

Amino acid modifications

Modified residue1121N6-(pyridoxal phosphate)lysine By similarity

Sequences

Sequence LengthMass (Da)Tools
Q4A041 [UniParc].

Last modified September 13, 2005. Version 1.
Checksum: FFE3D605DD45A407

FASTA43348,000
        10         20         30         40         50         60 
MNDLATLKQD FPLIDSMQNY KPIFWENPNF RKPASLTFTL KDMEDAAQRL ERFSSYISTV 

        70         80         90        100        110        120 
FPETENNHGL IESPLKHIPF MQNTLTNIES LPIEGKLWLK CDSHLAISGS IKARGGIYEV 

       130        140        150        160        170        180 
LKLAETIAMQ DGDLKETADY RVLAEQKYQD LFSKYNVAVG STGNLGLSIG IMSAKLGFKV 

       190        200        210        220        230        240 
TVHMSTDARQ WKKDLLRSRG VEVIEHQSDY QYAVAEGRKH AENDPTCHFV DDEGSSDLFL 

       250        260        270        280        290        300 
GYTVAALRLK AQLAAENIQI DAEHPLFVYI PCGVGGGPGG VTFGLKQVFG EHVYCIFTEP 

       310        320        330        340        350        360 
THAPCMLLGM MTQLHDKISV KDIGIDGNTD ADGLAVARPS RLVGQIMNTL LYGIQTVSDS 

       370        380        390        400        410        420 
EMYRYLYLLS EKEDIFIEPS AASGFAGIKS AITLAKQQGI QMNQANHIVW ATGGNMVPKE 

       430 
EMLKYVNHGK SCL

« Hide

References

[1]"Whole genome sequence of Staphylococcus saprophyticus reveals the pathogenesis of uncomplicated urinary tract infection."
Kuroda M., Yamashita A., Hirakawa H., Kumano M., Morikawa K., Higashide M., Maruyama A., Inose Y., Matoba K., Toh H., Kuhara S., Hattori M., Ohta T.
Proc. Natl. Acad. Sci. U.S.A. 102:13272-13277(2005) [PubMed: 16135568] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 15305 / DSM 20229.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP008934 Genomic DNA. Translation: BAE17577.1.
RefSeqYP_300522.1. NC_007350.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGQ4A041.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBSTAT00000047574; EBSTAP00000045943; EBSTAG00000047571.
GeneID3616180.
GenomeReviewsGene locus SSP0432 in contig AP008934_GR.
KEGGssp:SSP0432.
NMPDRfig|342451.4.peg.340.
PATRIC19622353. VBIStaSap90642_0437.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG3048.
HOGENOMHBG288722.
OMARFAPYIA.
PhylomeDBQ4A041.
ProtClustDBPRK02991.

Enzyme and pathway databases

BioCycSSAP342451:SSP0432-MONOMER.

Family and domain databases

HAMAPMF_01030. D-Ser_dehydrat.
[Tree]
InterProIPR011780. D_Ser_am_lyase.
IPR001926. PyrdxlP-dep_enz_bsu.
IPR000634. Ser/Thr_deHydtase_PyrdxlP-BS.
[Graphical view]
KOK01753.
PANTHERPTHR10314:SF9. D_Ser_am_lyase. 1 hit.
PfamPF00291. PALP. 1 hit.
[Graphical view]
SUPFAMSSF53686. PyrdxlP-dep_enz_bsu. 1 hit.
TIGRFAMsTIGR02035. D_Ser_am_lyase. 1 hit.
PROSITEPS00165. DEHYDRATASE_SER_THR. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSDHD_STAS1
AccessionPrimary (citable) accession number: Q4A041
Entry history
Integrated into UniProtKB/Swiss-Prot: June 26, 2007
Last sequence update: September 13, 2005
Last modified: January 25, 2012
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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