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Q49ZU9 (FENR_STAS1) Reviewed, UniProtKB/Swiss-Prot

Last modified May 29, 2013. Version 64. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ferredoxin--NADP reductase

Short name=FNR
Short name=Fd-NADP(+) reductase
EC=1.18.1.2
Gene names
Ordered Locus Names:SSP0530
OrganismStaphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229) [Complete proteome] [HAMAP]
Taxonomic identifier342451 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesStaphylococcus

Protein attributes

Sequence length343 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

2 reduced ferredoxin + NADP+ + H+ = 2 oxidized ferredoxin + NADPH. HAMAP-Rule MF_01685

Cofactor

Binds 1 FAD per subunit By similarity. HAMAP-Rule MF_01685

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_01685

Sequence similarities

Belongs to the ferredoxin--NADP reductase type 2 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 343343Ferredoxin--NADP reductase HAMAP-Rule MF_01685
PRO_0000364949

Sites

Binding site311FAD By similarity
Binding site391FAD By similarity
Binding site431FAD By similarity
Binding site831FAD; via amide nitrogen and carbonyl oxygen By similarity
Binding site1181FAD; via amide nitrogen By similarity
Binding site2851FAD By similarity
Binding site3261FAD By similarity

Sequences

Sequence LengthMass (Da)Tools
Q49ZU9 [UniParc].

Last modified September 13, 2005. Version 1.
Checksum: 255ECFF83A4C4639

FASTA34338,285
        10         20         30         40         50         60 
MDDVIIIGGG PAGLFASFYS GLRGMRVRII DIQDKLGGKM HVYPEKIIWD IGGLAPKPCF 

        70         80         90        100        110        120 
EVIQDTVKQG LHFEPEVNLE ERVIDIRKIE QQHFEVETDK GNVFSSKSVI IAIGGGIINP 

       130        140        150        160        170        180 
KQLDIKDAER YKLTNLHYVV QSLKKFKDKH VLISGAGNSA LDWANDLSGY AKSVTLIYRK 

       190        200        210        220        230        240 
ADIKGYEVMK EKLEQLNVKK LPNTHIHQLI GDETQTQIEQ VILENIETGE HTVKSFDDVI 

       250        260        270        280        290        300 
ISHGFDRENT LLEQSSAKVD MFNEYSIKGF GNTATSIDGL YACGDIIYHE AKAHLIASAF 

       310        320        330        340 
SDAANAANLA KLYIEPKAKA EGYVSSHNEI FKESNKVVMK KYL 

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References

[1]"Whole genome sequence of Staphylococcus saprophyticus reveals the pathogenesis of uncomplicated urinary tract infection."
Kuroda M., Yamashita A., Hirakawa H., Kumano M., Morikawa K., Higashide M., Maruyama A., Inose Y., Matoba K., Toh H., Kuhara S., Hattori M., Ohta T.
Proc. Natl. Acad. Sci. U.S.A. 102:13272-13277(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 15305 / DSM 20229.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP008934 Genomic DNA. Translation: BAE17675.1.
RefSeqYP_300620.1. NC_007350.1.

3D structure databases

ProteinModelPortalQ49ZU9.
ModBaseSearch...

Protein-protein interaction databases

STRING342451.SSP0530.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAE17675; BAE17675; SSP0530.
GeneID3614996.
KEGGssp:SSP0530.
PATRIC19622548. VBIStaSap90642_0534.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0492.
HOGENOMHOG000072909.
KOK00384.
OMAFNTSITK.
ProtClustDBCLSK885935.

Enzyme and pathway databases

BioCycSSAP342451:GKFA-532-MONOMER.

Family and domain databases

HAMAPMF_01685. FENR2.
InterProIPR013027. FAD_pyr_nucl-diS_OxRdtase.
IPR022890. Fd--NADP_Rdtase_type_2.
IPR023753. Pyr_nucl-diS_OxRdtase_FAD/NAD.
IPR001327. Pyr_OxRdtase_NAD-bd_dom.
IPR000103. Pyridine_nuc-diS_OxRdtase_2.
[Graphical view]
PfamPF00070. Pyr_redox. 1 hit.
PF07992. Pyr_redox_2. 1 hit.
[Graphical view]
PRINTSPR00368. FADPNR.
PR00469. PNDRDTASEII.
ProtoNetSearch...

Entry information

Entry nameFENR_STAS1
AccessionPrimary (citable) accession number: Q49ZU9
Entry history
Integrated into UniProtKB/Swiss-Prot: March 3, 2009
Last sequence update: September 13, 2005
Last modified: May 29, 2013
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families