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Protein

Putative 2-hydroxyacid dehydrogenase SSP0606

Gene

SSP0606

Organism
Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei237 – 2371By similarity
Binding sitei261 – 2611NADBy similarity
Active sitei266 – 2661By similarity
Active sitei284 – 2841Proton donorBy similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi156 – 1572NADBy similarity
Nucleotide bindingi235 – 2373NADBy similarity
Nucleotide bindingi284 – 2874NADBy similarity

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

NAD

Enzyme and pathway databases

BioCyciSSAP342451:GKFA-608-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative 2-hydroxyacid dehydrogenase SSP0606 (EC:1.1.1.-)
Gene namesi
Ordered Locus Names:SSP0606
OrganismiStaphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229)
Taxonomic identifieri342451 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus
ProteomesiUP000006371 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 318318Putative 2-hydroxyacid dehydrogenase SSP0606PRO_0000312192Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi342451.SSP0606.

Structurei

3D structure databases

ProteinModelPortaliQ49ZM5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG1052.
HOGENOMiHOG000136700.
OMAiHMIDTEQ.
OrthoDBiEOG6VXFC3.

Family and domain databases

Gene3Di3.40.50.720. 2 hits.
InterProiIPR006139. D-isomer_2_OHA_DH_cat_dom.
IPR006140. D-isomer_DH_NAD-bd.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamiPF00389. 2-Hacid_dh. 1 hit.
PF02826. 2-Hacid_dh_C. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q49ZM5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVKVYIAGPI PEVGLNLLKD QGFEVDMYEG TGIIDKETLK QGVKDADALI
60 70 80 90 100
SLLSTSVDKE VIDAANNLKI ITNYGAGFNN VDIDYARQQN IDVTNTPKAS
110 120 130 140 150
TNSTAELTFA LVLAVARRIP EGDKLCRTTG FDGWAPLFFR GREVSGKTIG
160 170 180 190 200
IIGLGEIGSA VARRAKAFDM NILYTGPHQK VDKEREIGAK YVDLETLLKN
210 220 230 240 250
ADFVTINAAY NPSLHHQIDK AQFEMMKPTS YLINASRGPI VHEKALVQAL
260 270 280 290 300
KDKEIEGAAL DVFEFEPEIN DELKTLDNVV ITPHIGNATF ESRDMMSKIV
310
ANDTISKLNN DQPKFIVN
Length:318
Mass (Da):34,974
Last modified:September 13, 2005 - v1
Checksum:i938DCFD425F8DD03
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP008934 Genomic DNA. Translation: BAE17751.1.
RefSeqiWP_002482556.1. NC_007350.1.
YP_300696.1. NC_007350.1.

Genome annotation databases

EnsemblBacteriaiBAE17751; BAE17751; SSP0606.
GeneIDi23780898.
KEGGissp:SSP0606.
PATRICi19622700. VBIStaSap90642_0610.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP008934 Genomic DNA. Translation: BAE17751.1.
RefSeqiWP_002482556.1. NC_007350.1.
YP_300696.1. NC_007350.1.

3D structure databases

ProteinModelPortaliQ49ZM5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi342451.SSP0606.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAE17751; BAE17751; SSP0606.
GeneIDi23780898.
KEGGissp:SSP0606.
PATRICi19622700. VBIStaSap90642_0610.

Phylogenomic databases

eggNOGiCOG1052.
HOGENOMiHOG000136700.
OMAiHMIDTEQ.
OrthoDBiEOG6VXFC3.

Enzyme and pathway databases

BioCyciSSAP342451:GKFA-608-MONOMER.

Family and domain databases

Gene3Di3.40.50.720. 2 hits.
InterProiIPR006139. D-isomer_2_OHA_DH_cat_dom.
IPR006140. D-isomer_DH_NAD-bd.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamiPF00389. 2-Hacid_dh. 1 hit.
PF02826. 2-Hacid_dh_C. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Whole genome sequence of Staphylococcus saprophyticus reveals the pathogenesis of uncomplicated urinary tract infection."
    Kuroda M., Yamashita A., Hirakawa H., Kumano M., Morikawa K., Higashide M., Maruyama A., Inose Y., Matoba K., Toh H., Kuhara S., Hattori M., Ohta T.
    Proc. Natl. Acad. Sci. U.S.A. 102:13272-13277(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 15305 / DSM 20229.

Entry informationi

Entry nameiY606_STAS1
AccessioniPrimary (citable) accession number: Q49ZM5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 4, 2007
Last sequence update: September 13, 2005
Last modified: May 27, 2015
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.