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Q49ZM5 (Y606_STAS1) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 63. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative 2-hydroxyacid dehydrogenase SSP0606

EC=1.1.1.-
Gene names
Ordered Locus Names:SSP0606
OrganismStaphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229) [Complete proteome] [HAMAP]
Taxonomic identifier342451 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesStaphylococcus

Protein attributes

Sequence length318 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 318318Putative 2-hydroxyacid dehydrogenase SSP0606
PRO_0000312192

Regions

Nucleotide binding156 – 1572NAD By similarity
Nucleotide binding235 – 2373NAD By similarity
Nucleotide binding284 – 2874NAD By similarity

Sites

Active site2371 By similarity
Active site2661 By similarity
Active site2841Proton donor By similarity
Binding site2611NAD By similarity

Sequences

Sequence LengthMass (Da)Tools
Q49ZM5 [UniParc].

Last modified September 13, 2005. Version 1.
Checksum: 938DCFD425F8DD03

FASTA31834,974
        10         20         30         40         50         60 
MVKVYIAGPI PEVGLNLLKD QGFEVDMYEG TGIIDKETLK QGVKDADALI SLLSTSVDKE 

        70         80         90        100        110        120 
VIDAANNLKI ITNYGAGFNN VDIDYARQQN IDVTNTPKAS TNSTAELTFA LVLAVARRIP 

       130        140        150        160        170        180 
EGDKLCRTTG FDGWAPLFFR GREVSGKTIG IIGLGEIGSA VARRAKAFDM NILYTGPHQK 

       190        200        210        220        230        240 
VDKEREIGAK YVDLETLLKN ADFVTINAAY NPSLHHQIDK AQFEMMKPTS YLINASRGPI 

       250        260        270        280        290        300 
VHEKALVQAL KDKEIEGAAL DVFEFEPEIN DELKTLDNVV ITPHIGNATF ESRDMMSKIV 

       310 
ANDTISKLNN DQPKFIVN 

« Hide

References

[1]"Whole genome sequence of Staphylococcus saprophyticus reveals the pathogenesis of uncomplicated urinary tract infection."
Kuroda M., Yamashita A., Hirakawa H., Kumano M., Morikawa K., Higashide M., Maruyama A., Inose Y., Matoba K., Toh H., Kuhara S., Hattori M., Ohta T.
Proc. Natl. Acad. Sci. U.S.A. 102:13272-13277(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 15305 / DSM 20229.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP008934 Genomic DNA. Translation: BAE17751.1.
RefSeqYP_300696.1. NC_007350.1.

3D structure databases

ProteinModelPortalQ49ZM5.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING342451.SSP0606.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAE17751; BAE17751; SSP0606.
GeneID3616100.
KEGGssp:SSP0606.
PATRIC19622700. VBIStaSap90642_0610.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1052.
HOGENOMHOG000136700.
OMASCEVIAN.
OrthoDBEOG6VXFC3.

Enzyme and pathway databases

BioCycSSAP342451:GKFA-608-MONOMER.

Family and domain databases

Gene3D3.40.50.720. 2 hits.
InterProIPR006139. D-isomer_2_OHA_DH_cat_dom.
IPR006140. D-isomer_2_OHA_DH_NAD-bd.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamPF00389. 2-Hacid_dh. 1 hit.
PF02826. 2-Hacid_dh_C. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameY606_STAS1
AccessionPrimary (citable) accession number: Q49ZM5
Entry history
Integrated into UniProtKB/Swiss-Prot: December 4, 2007
Last sequence update: September 13, 2005
Last modified: May 14, 2014
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families