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Q49ZM5

- Y606_STAS1

UniProt

Q49ZM5 - Y606_STAS1

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Protein

Putative 2-hydroxyacid dehydrogenase SSP0606

Gene

SSP0606

Organism
Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei237 – 2371By similarity
Binding sitei261 – 2611NADBy similarity
Active sitei266 – 2661By similarity
Active sitei284 – 2841Proton donorBy similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi156 – 1572NADBy similarity
Nucleotide bindingi235 – 2373NADBy similarity
Nucleotide bindingi284 – 2874NADBy similarity

GO - Molecular functioni

  1. NAD binding Source: InterPro
  2. oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

NAD

Enzyme and pathway databases

BioCyciSSAP342451:GKFA-608-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative 2-hydroxyacid dehydrogenase SSP0606 (EC:1.1.1.-)
Gene namesi
Ordered Locus Names:SSP0606
OrganismiStaphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229)
Taxonomic identifieri342451 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus
ProteomesiUP000006371: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 318318Putative 2-hydroxyacid dehydrogenase SSP0606PRO_0000312192Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi342451.SSP0606.

Structurei

3D structure databases

ProteinModelPortaliQ49ZM5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG1052.
HOGENOMiHOG000136700.
OMAiSCEVIAN.
OrthoDBiEOG6VXFC3.

Family and domain databases

Gene3Di3.40.50.720. 2 hits.
InterProiIPR006139. D-isomer_2_OHA_DH_cat_dom.
IPR006140. D-isomer_DH_NAD-bd.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamiPF00389. 2-Hacid_dh. 1 hit.
PF02826. 2-Hacid_dh_C. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q49ZM5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MVKVYIAGPI PEVGLNLLKD QGFEVDMYEG TGIIDKETLK QGVKDADALI
60 70 80 90 100
SLLSTSVDKE VIDAANNLKI ITNYGAGFNN VDIDYARQQN IDVTNTPKAS
110 120 130 140 150
TNSTAELTFA LVLAVARRIP EGDKLCRTTG FDGWAPLFFR GREVSGKTIG
160 170 180 190 200
IIGLGEIGSA VARRAKAFDM NILYTGPHQK VDKEREIGAK YVDLETLLKN
210 220 230 240 250
ADFVTINAAY NPSLHHQIDK AQFEMMKPTS YLINASRGPI VHEKALVQAL
260 270 280 290 300
KDKEIEGAAL DVFEFEPEIN DELKTLDNVV ITPHIGNATF ESRDMMSKIV
310
ANDTISKLNN DQPKFIVN
Length:318
Mass (Da):34,974
Last modified:September 13, 2005 - v1
Checksum:i938DCFD425F8DD03
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP008934 Genomic DNA. Translation: BAE17751.1.
RefSeqiYP_300696.1. NC_007350.1.

Genome annotation databases

EnsemblBacteriaiBAE17751; BAE17751; SSP0606.
GeneIDi3616100.
KEGGissp:SSP0606.
PATRICi19622700. VBIStaSap90642_0610.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP008934 Genomic DNA. Translation: BAE17751.1 .
RefSeqi YP_300696.1. NC_007350.1.

3D structure databases

ProteinModelPortali Q49ZM5.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 342451.SSP0606.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAE17751 ; BAE17751 ; SSP0606 .
GeneIDi 3616100.
KEGGi ssp:SSP0606.
PATRICi 19622700. VBIStaSap90642_0610.

Phylogenomic databases

eggNOGi COG1052.
HOGENOMi HOG000136700.
OMAi SCEVIAN.
OrthoDBi EOG6VXFC3.

Enzyme and pathway databases

BioCyci SSAP342451:GKFA-608-MONOMER.

Family and domain databases

Gene3Di 3.40.50.720. 2 hits.
InterProi IPR006139. D-isomer_2_OHA_DH_cat_dom.
IPR006140. D-isomer_DH_NAD-bd.
IPR016040. NAD(P)-bd_dom.
[Graphical view ]
Pfami PF00389. 2-Hacid_dh. 1 hit.
PF02826. 2-Hacid_dh_C. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Whole genome sequence of Staphylococcus saprophyticus reveals the pathogenesis of uncomplicated urinary tract infection."
    Kuroda M., Yamashita A., Hirakawa H., Kumano M., Morikawa K., Higashide M., Maruyama A., Inose Y., Matoba K., Toh H., Kuhara S., Hattori M., Ohta T.
    Proc. Natl. Acad. Sci. U.S.A. 102:13272-13277(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 15305 / DSM 20229.

Entry informationi

Entry nameiY606_STAS1
AccessioniPrimary (citable) accession number: Q49ZM5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 4, 2007
Last sequence update: September 13, 2005
Last modified: October 1, 2014
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3