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Q49ZM5

- Y606_STAS1

UniProt

Q49ZM5 - Y606_STAS1

Protein

Putative 2-hydroxyacid dehydrogenase SSP0606

Gene

SSP0606

Organism
Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 65 (01 Oct 2014)
      Sequence version 1 (13 Sep 2005)
      Previous versions | rss
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    Functioni

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei237 – 2371By similarity
    Binding sitei261 – 2611NADBy similarity
    Active sitei266 – 2661By similarity
    Active sitei284 – 2841Proton donorBy similarity

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi156 – 1572NADBy similarity
    Nucleotide bindingi235 – 2373NADBy similarity
    Nucleotide bindingi284 – 2874NADBy similarity

    GO - Molecular functioni

    1. NAD binding Source: InterPro
    2. oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Source: InterPro

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Ligandi

    NAD

    Enzyme and pathway databases

    BioCyciSSAP342451:GKFA-608-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Putative 2-hydroxyacid dehydrogenase SSP0606 (EC:1.1.1.-)
    Gene namesi
    Ordered Locus Names:SSP0606
    OrganismiStaphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229)
    Taxonomic identifieri342451 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus
    ProteomesiUP000006371: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 318318Putative 2-hydroxyacid dehydrogenase SSP0606PRO_0000312192Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi342451.SSP0606.

    Structurei

    3D structure databases

    ProteinModelPortaliQ49ZM5.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG1052.
    HOGENOMiHOG000136700.
    OMAiSCEVIAN.
    OrthoDBiEOG6VXFC3.

    Family and domain databases

    Gene3Di3.40.50.720. 2 hits.
    InterProiIPR006139. D-isomer_2_OHA_DH_cat_dom.
    IPR006140. D-isomer_DH_NAD-bd.
    IPR016040. NAD(P)-bd_dom.
    [Graphical view]
    PfamiPF00389. 2-Hacid_dh. 1 hit.
    PF02826. 2-Hacid_dh_C. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q49ZM5-1 [UniParc]FASTAAdd to Basket

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    MVKVYIAGPI PEVGLNLLKD QGFEVDMYEG TGIIDKETLK QGVKDADALI    50
    SLLSTSVDKE VIDAANNLKI ITNYGAGFNN VDIDYARQQN IDVTNTPKAS 100
    TNSTAELTFA LVLAVARRIP EGDKLCRTTG FDGWAPLFFR GREVSGKTIG 150
    IIGLGEIGSA VARRAKAFDM NILYTGPHQK VDKEREIGAK YVDLETLLKN 200
    ADFVTINAAY NPSLHHQIDK AQFEMMKPTS YLINASRGPI VHEKALVQAL 250
    KDKEIEGAAL DVFEFEPEIN DELKTLDNVV ITPHIGNATF ESRDMMSKIV 300
    ANDTISKLNN DQPKFIVN 318
    Length:318
    Mass (Da):34,974
    Last modified:September 13, 2005 - v1
    Checksum:i938DCFD425F8DD03
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP008934 Genomic DNA. Translation: BAE17751.1.
    RefSeqiYP_300696.1. NC_007350.1.

    Genome annotation databases

    EnsemblBacteriaiBAE17751; BAE17751; SSP0606.
    GeneIDi3616100.
    KEGGissp:SSP0606.
    PATRICi19622700. VBIStaSap90642_0610.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP008934 Genomic DNA. Translation: BAE17751.1 .
    RefSeqi YP_300696.1. NC_007350.1.

    3D structure databases

    ProteinModelPortali Q49ZM5.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 342451.SSP0606.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAE17751 ; BAE17751 ; SSP0606 .
    GeneIDi 3616100.
    KEGGi ssp:SSP0606.
    PATRICi 19622700. VBIStaSap90642_0610.

    Phylogenomic databases

    eggNOGi COG1052.
    HOGENOMi HOG000136700.
    OMAi SCEVIAN.
    OrthoDBi EOG6VXFC3.

    Enzyme and pathway databases

    BioCyci SSAP342451:GKFA-608-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.720. 2 hits.
    InterProi IPR006139. D-isomer_2_OHA_DH_cat_dom.
    IPR006140. D-isomer_DH_NAD-bd.
    IPR016040. NAD(P)-bd_dom.
    [Graphical view ]
    Pfami PF00389. 2-Hacid_dh. 1 hit.
    PF02826. 2-Hacid_dh_C. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Whole genome sequence of Staphylococcus saprophyticus reveals the pathogenesis of uncomplicated urinary tract infection."
      Kuroda M., Yamashita A., Hirakawa H., Kumano M., Morikawa K., Higashide M., Maruyama A., Inose Y., Matoba K., Toh H., Kuhara S., Hattori M., Ohta T.
      Proc. Natl. Acad. Sci. U.S.A. 102:13272-13277(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 15305 / DSM 20229.

    Entry informationi

    Entry nameiY606_STAS1
    AccessioniPrimary (citable) accession number: Q49ZM5
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 4, 2007
    Last sequence update: September 13, 2005
    Last modified: October 1, 2014
    This is version 65 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3