Reviewed, UniProtKB/Swiss-Prot Q49ZK0 (GALT_STAS1)

Names and origin

Protein names

Recommended name:
    Galactose-1-phosphate uridylyltransferase
      Short name=Gal-1-P uridylyltransferase
    EC=2.7.7.12
Alternative name(s):
    UDP-glucose--hexose-1-phosphate uridylyltransferase

Gene names

Name:	galT
Ordered Locus Names:	SSP0631

Organism

Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229) [Complete proteome] [HAMAP]

Taxonomic identifier

342451 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Staphylococcus

Protein attributes

Sequence length	496 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	UDP-glucose + alpha-D-galactose 1-phosphate = alpha-D-glucose 1-phosphate + UDP-galactose. HAMAP MF_00571
Pathway	Carbohydrate metabolism; galactose metabolism. HAMAP MF_00571
Subcellular location	Cytoplasm Potential HAMAP MF_00571.
Sequence similarities	Belongs to the galactose-1-phosphate uridylyltransferase type 2 family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism Galactose metabolism
Cellular component	Cytoplasm
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	galactose metabolic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	UDP-glucose:hexose-1-phosphate uridylyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 496	496	Galactose-1-phosphate uridylyltransferase HAMAP MF_00571		PRO_1000025027

Sequences

	Sequence		Length	Mass (Da)
	Q49ZK0-1 [UniParc]. Last modified September 13, 2005. Version 1. Checksum: AF39FBA1ABDB80D3	FASTA	496	57,233
	10 20 30 40 50 60 MLLNQQLVQQ FVTQAIAFGD YEQEDNIYIQ NQLLRILNAI GIDVDNESPL NQDATANAIA 70 80 90 100 110 120 QYWIEQAVNE NYLEDALYKK EIVEAQILDL ITPRPSVINR NFVEAYKKSP ETATNYFYEI 130 140 150 160 170 180 TKRNHYVKED AIANNINYEV ETEYGDIEIT INLSKPEKDA KQIAKAKAEP AKHYPKCALC 190 200 210 220 230 240 IENEGYQGSV TQAARTNHRI IRLKLDGKSW GFQYSPYAYF PEHSIVLSEH HVPMEINKQT 250 260 270 280 290 300 FVNLLAFIEQ FPHYFIGSNA DIPLVGGSIL SHNHYQAGKH VFPMDNAAEI ERFTMNQFSS 310 320 330 340 350 360 VTASTLNWPM SVIRLKSENR DELINAATYV MNTWNQYSDE TIDVRAFSKD GERHHTVTPI 370 380 390 400 410 420 ARYRQSQYEL DIVLRDNQTS EVFPDGIFHP HEDVQHIKKE NIGLIEVMGT AILPGRLKEE 430 440 450 460 470 480 LQQVKTYLVG DNQFDLGIHQ QWAENMKRTY DINKQNVDDI VDKEVGYKFK RVLEDAGVFK 490 NTDTGRQAFK RFIKHL

References

[1]

"Whole genome sequence of Staphylococcus saprophyticus reveals the pathogenesis of uncomplicated urinary tract infection." Kuroda M., Yamashita A., Hirakawa H., Kumano M., Morikawa K., Higashide M., Maruyama A., Inose Y., Matoba K., Toh H., Kuhara S., Hattori M., Ohta T. Proc. Natl. Acad. Sci. U.S.A. 102:13272-13277(2005) [PubMed: 16135568] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP008934 Genomic DNA. Translation: BAE17776.1.
RefSeq	YP_300721.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q49ZK0.
Genome annotation databases
GeneID	3616027.
GenomeReviews	Gene locus SSP0631 in contig AP008934_GR.
KEGG	ssp:SSP0631.
NMPDR	fig|342451.4.peg.810.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG4468.
HOGENOM	HBG337915.
OMA	EHYQGGR.
Enzyme and pathway databases
BioCyc	SSAP342451:SSP0631-MONOMER.
Family and domain databases
HAMAP	MF_00571. GalP_UDP_trans. [Tree]
InterPro	IPR000766. GalP_uridyl_Trfase_II. IPR005850. GalP_Utransf_C. IPR005849. GalP_Utransf_N. [Graphical view]
Pfam	PF02744. GalP_UDP_tr_C. 1 hit. PF01087. GalP_UDP_transf. 1 hit. [Graphical view]
PIRSF	PIRSF006005. GalT_BS. 1 hit.
TIGRFAMs	TIGR01239. galT_2. 1 hit.
PROSITE	PS01163. GAL_P_UDP_TRANSF_II. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GALT_STAS1

Accession

Primary (citable) accession number: Q49ZK0

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	September 13, 2005
Last modified:	February 9, 2010
This is version 25 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)