Q49ZA7 (GLMM_STAS1) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phosphoglucosamine mutase
EC=5.4.2.10

Gene names

Name:	glmM
Ordered Locus Names:	SSP0724

Organism

Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229) [Complete proteome] [HAMAP]

Taxonomic identifier

342451 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Staphylococcus

Protein attributes

Sequence length	451 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate By similarity. HAMAP MF_01554_B
Catalytic activity	Alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate. HAMAP MF_01554_B
Cofactor	Binds 1 magnesium ion per subunit By similarity. HAMAP MF_01554_B
Post-translational modification	Activated by phosphorylation By similarity. HAMAP MF_01554_B
Sequence similarities	Belongs to the phosphohexose mutase family.

Ontologies

Keywords
Ligand	Magnesium Metal-binding
Molecular function	Isomerase
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	magnesium ion binding Inferred from electronic annotation. Source: InterPro phosphoglucosamine mutase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 451	451	Phosphoglucosamine mutase HAMAP MF_01554_B		PRO_0000147968
Sites
	Active site	102	1	Phosphoserine intermediate By similarity
	Metal binding	102	1	Magnesium; via phosphate group By similarity
	Metal binding	242	1	Magnesium By similarity
	Metal binding	244	1	Magnesium By similarity
	Metal binding	246	1	Magnesium By similarity
Amino acid modifications
	Modified residue	102	1	Phosphoserine By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q49ZA7 [UniParc]. Last modified September 13, 2005. Version 1. Checksum: 3FBCE030614CB100	FASTA	451	49,182
	10 20 30 40 50 60 MAKYFGTDGV RGVANKELTP ELAFKLGRYG GYVLAHNEGE KHPKVLVGRD TRVSGEMLES 70 80 90 100 110 120 ALIAGLISIG AEVMRLGVIS TPGVAYLTRE MEADLGVMIS ASHNPVPDNG IKFFGSDGFK 130 140 150 160 170 180 LSDDQEQEIE HLLDQDNPDL PRPVGEDIVH YSDYFEGAQK YISYLKSTVD VDLAGMKIAL 190 200 210 220 230 240 DGAHGSTSSL APFLFGDLEA DTVTIGCNPN GYNINQEVGS THPESLAKVV VESECDFGLA 250 260 270 280 290 300 FDGDGDRLIA IDEKGNIVDG DQIMFIIGQA MSKNQELNNN MIVSTVMSNL GFYKALENEG 310 320 330 340 350 360 IQSNKTKVGD RYVVEEMRRG NYNLGGEQSG HIVLMDYNTT GDGLLTGVQL ASIIKMTGKS 370 380 390 400 410 420 LSQLTSQMKK YPQSLVNVRV TDKYRVEENI DVQEIMTKVE VEMNGEGRIL VRPSGTEPLV 430 440 450 RVMVEAATDE DAQRYANTIA EVVQDKMGLD N

References

[1]

"Whole genome sequence of Staphylococcus saprophyticus reveals the pathogenesis of uncomplicated urinary tract infection." Kuroda M., Yamashita A., Hirakawa H., Kumano M., Morikawa K., Higashide M., Maruyama A., Inose Y., Matoba K., Toh H., Kuhara S., Hattori M., Ohta T. Proc. Natl. Acad. Sci. U.S.A. 102:13272-13277(2005) [PubMed: 16135568] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 15305 / DSM 20229.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP008934 Genomic DNA. Translation: BAE17869.1.
RefSeq	YP_300814.1. NC_007350.1.
3D structure databases
ProteinModelPortal	Q49ZA7.
ModBase	Search...
Protein-protein interaction databases
STRING	Q49ZA7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBSTAT00000047604; EBSTAP00000045973; EBSTAG00000047601.
GeneID	3615925.
GenomeReviews	Gene locus SSP0724 in contig AP008934_GR.
KEGG	ssp:SSP0724.
NMPDR	fig|342451.4.peg.1137.
PATRIC	19622950. VBIStaSap90642_0726.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1109.
GeneTree	EBGT00050000024615.
HOGENOM	HBG644964.
OMA	GVGSTHL.
PhylomeDB	Q49ZA7.
ProtClustDB	PRK14316.
Enzyme and pathway databases
BioCyc	SSAP342451:SSP0724-MONOMER.
Family and domain databases
HAMAP	MF_01554_B. GlmM_B. [Tree]
InterPro	IPR005844. A-D-PHexomutase_a/b/a-I. IPR016055. A-D-PHexomutase_a/b/a-I/II/III. IPR005845. A-D-PHexomutase_a/b/a-II. IPR005846. A-D-PHexomutase_a/b/a-III. IPR005843. A-D-PHexomutase_C. IPR016066. A-D-PHexomutase_CS. IPR005841. Alpha-D-phosphohexomutase_SF. IPR006352. GlmM. [Graphical view]
Gene3D	G3DSA:3.40.120.10. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
KO	K03431.
Pfam	PF02878. PGM_PMM_I. 1 hit. PF02879. PGM_PMM_II. 1 hit. PF02880. PGM_PMM_III. 1 hit. PF00408. PGM_PMM_IV. 1 hit. [Graphical view]
PRINTS	PR00509. PGMPMM.
SUPFAM	SSF53738. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
TIGRFAMs	TIGR01455. GlmM. 1 hit.
PROSITE	PS00710. PGM_PMM. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLMM_STAS1

Accession

Primary (citable) accession number: Q49ZA7

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 20, 2005
Last sequence update:	September 13, 2005
Last modified:	January 25, 2012
This is version 44 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program