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Q49Z69

- ALD1_STAS1

UniProt

Q49Z69 - ALD1_STAS1

Protein

Putative aldehyde dehydrogenase SSP0762

Gene

SSP0762

Organism
Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 62 (01 Oct 2014)
      Sequence version 1 (13 Sep 2005)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    An aldehyde + NAD+ + H2O = a carboxylate + NADH.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei245 – 2451By similarity
    Active sitei279 – 2791By similarity

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi201 – 2077NADBy similarity

    GO - Molecular functioni

    1. aldehyde dehydrogenase (NAD) activity Source: UniProtKB-EC

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Ligandi

    NAD

    Enzyme and pathway databases

    BioCyciRETL1328306-WGS:GSTH-4792-MONOMER.
    RETL1328306-WGS:GSTH-5716-MONOMER.
    SSAP342451:GKFA-774-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Putative aldehyde dehydrogenase SSP0762 (EC:1.2.1.3)
    Gene namesi
    Ordered Locus Names:SSP0762
    OrganismiStaphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229)
    Taxonomic identifieri342451 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus
    ProteomesiUP000006371: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 475475Putative aldehyde dehydrogenase SSP0762PRO_0000293564Add
    BLAST

    Proteomic databases

    PRIDEiQ49Z69.

    Interactioni

    Protein-protein interaction databases

    STRINGi342451.SSP0762.

    Structurei

    3D structure databases

    ProteinModelPortaliQ49Z69.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the aldehyde dehydrogenase family.Curated

    Phylogenomic databases

    eggNOGiCOG1012.
    HOGENOMiHOG000271505.
    KOiK00128.
    OMAiCSIPTRM.
    OrthoDBiEOG6BS8QW.

    Family and domain databases

    Gene3Di3.40.309.10. 1 hit.
    3.40.605.10. 1 hit.
    InterProiIPR016161. Ald_DH/histidinol_DH.
    IPR016163. Ald_DH_C.
    IPR016160. Ald_DH_CS_CYS.
    IPR029510. Ald_DH_CS_GLU.
    IPR016162. Ald_DH_N.
    IPR015590. Aldehyde_DH_dom.
    [Graphical view]
    PfamiPF00171. Aldedh. 1 hit.
    [Graphical view]
    SUPFAMiSSF53720. SSF53720. 1 hit.
    PROSITEiPS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
    PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q49Z69-1 [UniParc]FASTAAdd to Basket

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    MRNFTKQYIN GEWVESTSGE TLEVINPATE EVAGTIAKGN KEDVEKAVEA    50
    ADNVYLEFRH TSVKERQDLL DQIVQEYKNR KEDLIQAITD ELGAPLSVAE 100
    NVHYQMGLDH FEAARDALND FQFEERRGDD LVVKEAIGVS GLITPWNFPT 150
    NQTSLKLAAA FAAGSPVVFK PSEETPFAAI ILAEIFDKVG VPKGVFNLVN 200
    GDGQGVGNPL SEHPKVRMMS FTGSGPTGSS IMKKAAEDFK KVSLELGGKS 250
    PYIILDDADI DGAASAAANK VVFNTGQVCT AGTRTIVPAS IKEDFLTAVK 300
    EKFSQVKVGN PREEGTQVGP IISKKQFDQV QAYIDKGIEE GAELLYGGPG 350
    KPEGLDKGYF ARPTIFNNVD NSMTIAQEEI FGPVMSVITY NDLDEAIKIA 400
    NDTKYGLAGY VYGSDKDTLH KVARSIEAGT VEINEAGRKP DLPFGGYKQS 450
    GLGREWGDYG IEEFLEVKSI AGYYN 475
    Length:475
    Mass (Da):51,651
    Last modified:September 13, 2005 - v1
    Checksum:i9A71EA22E5FE487B
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP008934 Genomic DNA. Translation: BAE17907.1.
    RefSeqiWP_011302667.1. NC_007350.1.
    YP_300852.1. NC_007350.1.

    Genome annotation databases

    EnsemblBacteriaiBAE17907; BAE17907; SSP0762.
    GeneIDi3615827.
    KEGGissp:SSP0762.
    PATRICi19623026. VBIStaSap90642_0764.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP008934 Genomic DNA. Translation: BAE17907.1 .
    RefSeqi WP_011302667.1. NC_007350.1.
    YP_300852.1. NC_007350.1.

    3D structure databases

    ProteinModelPortali Q49Z69.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 342451.SSP0762.

    Proteomic databases

    PRIDEi Q49Z69.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAE17907 ; BAE17907 ; SSP0762 .
    GeneIDi 3615827.
    KEGGi ssp:SSP0762.
    PATRICi 19623026. VBIStaSap90642_0764.

    Phylogenomic databases

    eggNOGi COG1012.
    HOGENOMi HOG000271505.
    KOi K00128.
    OMAi CSIPTRM.
    OrthoDBi EOG6BS8QW.

    Enzyme and pathway databases

    BioCyci RETL1328306-WGS:GSTH-4792-MONOMER.
    RETL1328306-WGS:GSTH-5716-MONOMER.
    SSAP342451:GKFA-774-MONOMER.

    Family and domain databases

    Gene3Di 3.40.309.10. 1 hit.
    3.40.605.10. 1 hit.
    InterProi IPR016161. Ald_DH/histidinol_DH.
    IPR016163. Ald_DH_C.
    IPR016160. Ald_DH_CS_CYS.
    IPR029510. Ald_DH_CS_GLU.
    IPR016162. Ald_DH_N.
    IPR015590. Aldehyde_DH_dom.
    [Graphical view ]
    Pfami PF00171. Aldedh. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53720. SSF53720. 1 hit.
    PROSITEi PS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
    PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Whole genome sequence of Staphylococcus saprophyticus reveals the pathogenesis of uncomplicated urinary tract infection."
      Kuroda M., Yamashita A., Hirakawa H., Kumano M., Morikawa K., Higashide M., Maruyama A., Inose Y., Matoba K., Toh H., Kuhara S., Hattori M., Ohta T.
      Proc. Natl. Acad. Sci. U.S.A. 102:13272-13277(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 15305 / DSM 20229.

    Entry informationi

    Entry nameiALD1_STAS1
    AccessioniPrimary (citable) accession number: Q49Z69
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 10, 2007
    Last sequence update: September 13, 2005
    Last modified: October 1, 2014
    This is version 62 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3