Reviewed, UniProtKB/Swiss-Prot Q49Z69 (ALD1_STAS1)

Names and origin

Protein names

Recommended name:
    Putative aldehyde dehydrogenase SSP0762
    EC=1.2.1.3

Gene names

Ordered Locus Names:

SSP0762

Organism

Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229) [Complete proteome] [HAMAP]

Taxonomic identifier

342451 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Staphylococcus

Protein attributes

Sequence length	475 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	An aldehyde + NAD+ + H2O = an acid + NADH.
Sequence similarities	Belongs to the aldehyde dehydrogenase family.

Ontologies

Keywords
Ligand	NAD
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	aldehyde dehydrogenase (NAD) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 475	475	Putative aldehyde dehydrogenase SSP0762		PRO_0000293564
Regions
	Nucleotide binding	201 – 207	7	NAD By similarity
Sites
	Active site	245	1	By similarity
	Active site	279	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q49Z69-1 [UniParc]. Last modified September 13, 2005. Version 1. Checksum: 9A71EA22E5FE487B	FASTA	475	51,651
	10 20 30 40 50 60 MRNFTKQYIN GEWVESTSGE TLEVINPATE EVAGTIAKGN KEDVEKAVEA ADNVYLEFRH 70 80 90 100 110 120 TSVKERQDLL DQIVQEYKNR KEDLIQAITD ELGAPLSVAE NVHYQMGLDH FEAARDALND 130 140 150 160 170 180 FQFEERRGDD LVVKEAIGVS GLITPWNFPT NQTSLKLAAA FAAGSPVVFK PSEETPFAAI 190 200 210 220 230 240 ILAEIFDKVG VPKGVFNLVN GDGQGVGNPL SEHPKVRMMS FTGSGPTGSS IMKKAAEDFK 250 260 270 280 290 300 KVSLELGGKS PYIILDDADI DGAASAAANK VVFNTGQVCT AGTRTIVPAS IKEDFLTAVK 310 320 330 340 350 360 EKFSQVKVGN PREEGTQVGP IISKKQFDQV QAYIDKGIEE GAELLYGGPG KPEGLDKGYF 370 380 390 400 410 420 ARPTIFNNVD NSMTIAQEEI FGPVMSVITY NDLDEAIKIA NDTKYGLAGY VYGSDKDTLH 430 440 450 460 470 KVARSIEAGT VEINEAGRKP DLPFGGYKQS GLGREWGDYG IEEFLEVKSI AGYYN

References

[1]

"Whole genome sequence of Staphylococcus saprophyticus reveals the pathogenesis of uncomplicated urinary tract infection." Kuroda M., Yamashita A., Hirakawa H., Kumano M., Morikawa K., Higashide M., Maruyama A., Inose Y., Matoba K., Toh H., Kuhara S., Hattori M., Ohta T. Proc. Natl. Acad. Sci. U.S.A. 102:13272-13277(2005) [PubMed: 16135568] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AP008934 Genomic DNA. Translation: BAE17907.1.
RefSeq	YP_300852.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3615827.
GenomeReviews	Gene locus SSP0762 in contig AP008934_GR.
KEGG	ssp:SSP0762.
NMPDR	fig|342451.4.peg.1277.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q49Z69.
OMA	Q49Z69. QITINNA.
Enzyme and pathway databases
BioCyc	SSAP342451:SSP0762-MON.
Family and domain databases
InterPro	IPR016160. Ald_DH_CS. IPR016162. Ald_DH_N. IPR015590. Aldehyde_DH. [Graphical view]
Gene3D	G3DSA:3.40.605.10. Aldehyde_dehydrogenase_N. 1 hit.
PANTHER	PTHR11699. Aldehyde_dehyd. 1 hit.
Pfam	PF00171. Aldedh. 1 hit. [Graphical view]
PROSITE	PS00070. ALDEHYDE_DEHYDR_CYS. 1 hit. PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ALD1_STAS1

Accession

Primary (citable) accession number: Q49Z69

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 10, 2007
Last sequence update:	September 13, 2005
Last modified:	June 16, 2009
This is version 25 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)