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Q49Z69 (ALD1_STAS1) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 45. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Putative aldehyde dehydrogenase SSP0762
EC=1.2.1.3
Gene names
Ordered Locus Names:SSP0762
OrganismStaphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229) [Complete proteome] [HAMAP]
Taxonomic identifier342451 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Staphylococcus

Protein attributes

Sequence length475 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

An aldehyde + NAD+ + H2O = a carboxylate + NADH.

Sequence similarities

Belongs to the aldehyde dehydrogenase family.

Ontologies

Keywords
   LigandNAD
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Molecular functionaldehyde dehydrogenase (NAD) activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 475475Putative aldehyde dehydrogenase SSP0762
PRO_0000293564

Regions

Nucleotide binding201 – 2077NAD By similarity

Sites

Active site2451 By similarity
Active site2791 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q49Z69 [UniParc].

Last modified September 13, 2005. Version 1.
Checksum: 9A71EA22E5FE487B

FASTA47551,651
        10         20         30         40         50         60 
MRNFTKQYIN GEWVESTSGE TLEVINPATE EVAGTIAKGN KEDVEKAVEA ADNVYLEFRH 

        70         80         90        100        110        120 
TSVKERQDLL DQIVQEYKNR KEDLIQAITD ELGAPLSVAE NVHYQMGLDH FEAARDALND 

       130        140        150        160        170        180 
FQFEERRGDD LVVKEAIGVS GLITPWNFPT NQTSLKLAAA FAAGSPVVFK PSEETPFAAI 

       190        200        210        220        230        240 
ILAEIFDKVG VPKGVFNLVN GDGQGVGNPL SEHPKVRMMS FTGSGPTGSS IMKKAAEDFK 

       250        260        270        280        290        300 
KVSLELGGKS PYIILDDADI DGAASAAANK VVFNTGQVCT AGTRTIVPAS IKEDFLTAVK 

       310        320        330        340        350        360 
EKFSQVKVGN PREEGTQVGP IISKKQFDQV QAYIDKGIEE GAELLYGGPG KPEGLDKGYF 

       370        380        390        400        410        420 
ARPTIFNNVD NSMTIAQEEI FGPVMSVITY NDLDEAIKIA NDTKYGLAGY VYGSDKDTLH 

       430        440        450        460        470 
KVARSIEAGT VEINEAGRKP DLPFGGYKQS GLGREWGDYG IEEFLEVKSI AGYYN

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References

[1]"Whole genome sequence of Staphylococcus saprophyticus reveals the pathogenesis of uncomplicated urinary tract infection."
Kuroda M., Yamashita A., Hirakawa H., Kumano M., Morikawa K., Higashide M., Maruyama A., Inose Y., Matoba K., Toh H., Kuhara S., Hattori M., Ohta T.
Proc. Natl. Acad. Sci. U.S.A. 102:13272-13277(2005) [PubMed: 16135568] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 15305 / DSM 20229.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP008934 Genomic DNA. Translation: BAE17907.1.
RefSeqYP_300852.1. NC_007350.1.

3D structure databases

HSSPHSSP built from PDB template 2D4E based on UniProtKB Q5SJP9.
ProteinModelPortalQ49Z69.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ49Z69.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBSTAT00000047730; EBSTAP00000046099; EBSTAG00000047727.
GeneID3615827.
GenomeReviewsGene locus SSP0762 in contig AP008934_GR.
KEGGssp:SSP0762.
NMPDRfig|342451.4.peg.1277.
PATRIC19623026. VBIStaSap90642_0764.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1012.
GeneTreeEBGT00050000023967.
HOGENOMHBG752218.
OMASPYIILD.
PhylomeDBQ49Z69.
ProtClustDBCLSK885774.

Enzyme and pathway databases

BioCycSSAP342451:SSP0762-MONOMER.

Family and domain databases

InterProIPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR016160. Ald_DH_CS.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
[Graphical view]
Gene3DG3DSA:3.40.309.10. Aldehyde_dehydrogenase_C. 1 hit.
G3DSA:3.40.605.10. Aldehyde_dehydrogenase_N. 1 hit.
KOK00128.
PfamPF00171. Aldedh. 1 hit.
[Graphical view]
SUPFAMSSF53720. Aldehyde_DH/Histidinol_DH. 1 hit.
PROSITEPS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameALD1_STAS1
AccessionPrimary (citable) accession number: Q49Z69
Entry history
Integrated into UniProtKB/Swiss-Prot: July 10, 2007
Last sequence update: September 13, 2005
Last modified: January 25, 2012
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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