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Protein

Putative aldehyde dehydrogenase SSP0762

Gene

SSP0762

Organism
Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

An aldehyde + NAD+ + H2O = a carboxylate + NADH.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei245 – 2451By similarity
Active sitei279 – 2791By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi201 – 2077NADBy similarity

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

NAD

Enzyme and pathway databases

BioCyciRETL1328306-WGS:GSTH-4792-MONOMER.
RETL1328306-WGS:GSTH-5716-MONOMER.
SSAP342451:GKFA-774-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative aldehyde dehydrogenase SSP0762 (EC:1.2.1.3)
Gene namesi
Ordered Locus Names:SSP0762
OrganismiStaphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229)
Taxonomic identifieri342451 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus
ProteomesiUP000006371 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 475475Putative aldehyde dehydrogenase SSP0762PRO_0000293564Add
BLAST

Proteomic databases

PRIDEiQ49Z69.

Interactioni

Protein-protein interaction databases

STRINGi342451.SSP0762.

Structurei

3D structure databases

ProteinModelPortaliQ49Z69.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the aldehyde dehydrogenase family.Curated

Phylogenomic databases

eggNOGiCOG1012.
HOGENOMiHOG000271505.
KOiK00128.
OMAiSGMVEMN.
OrthoDBiEOG6BS8QW.

Family and domain databases

Gene3Di3.40.309.10. 1 hit.
3.40.605.10. 1 hit.
InterProiIPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR016160. Ald_DH_CS_CYS.
IPR029510. Ald_DH_CS_GLU.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
[Graphical view]
PfamiPF00171. Aldedh. 1 hit.
[Graphical view]
SUPFAMiSSF53720. SSF53720. 1 hit.
PROSITEiPS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q49Z69-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRNFTKQYIN GEWVESTSGE TLEVINPATE EVAGTIAKGN KEDVEKAVEA
60 70 80 90 100
ADNVYLEFRH TSVKERQDLL DQIVQEYKNR KEDLIQAITD ELGAPLSVAE
110 120 130 140 150
NVHYQMGLDH FEAARDALND FQFEERRGDD LVVKEAIGVS GLITPWNFPT
160 170 180 190 200
NQTSLKLAAA FAAGSPVVFK PSEETPFAAI ILAEIFDKVG VPKGVFNLVN
210 220 230 240 250
GDGQGVGNPL SEHPKVRMMS FTGSGPTGSS IMKKAAEDFK KVSLELGGKS
260 270 280 290 300
PYIILDDADI DGAASAAANK VVFNTGQVCT AGTRTIVPAS IKEDFLTAVK
310 320 330 340 350
EKFSQVKVGN PREEGTQVGP IISKKQFDQV QAYIDKGIEE GAELLYGGPG
360 370 380 390 400
KPEGLDKGYF ARPTIFNNVD NSMTIAQEEI FGPVMSVITY NDLDEAIKIA
410 420 430 440 450
NDTKYGLAGY VYGSDKDTLH KVARSIEAGT VEINEAGRKP DLPFGGYKQS
460 470
GLGREWGDYG IEEFLEVKSI AGYYN
Length:475
Mass (Da):51,651
Last modified:September 13, 2005 - v1
Checksum:i9A71EA22E5FE487B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP008934 Genomic DNA. Translation: BAE17907.1.
RefSeqiWP_011302667.1. NC_007350.1.
YP_300852.1. NC_007350.1.

Genome annotation databases

EnsemblBacteriaiBAE17907; BAE17907; SSP0762.
GeneIDi23780735.
KEGGissp:SSP0762.
PATRICi19623026. VBIStaSap90642_0764.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP008934 Genomic DNA. Translation: BAE17907.1.
RefSeqiWP_011302667.1. NC_007350.1.
YP_300852.1. NC_007350.1.

3D structure databases

ProteinModelPortaliQ49Z69.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi342451.SSP0762.

Proteomic databases

PRIDEiQ49Z69.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAE17907; BAE17907; SSP0762.
GeneIDi23780735.
KEGGissp:SSP0762.
PATRICi19623026. VBIStaSap90642_0764.

Phylogenomic databases

eggNOGiCOG1012.
HOGENOMiHOG000271505.
KOiK00128.
OMAiSGMVEMN.
OrthoDBiEOG6BS8QW.

Enzyme and pathway databases

BioCyciRETL1328306-WGS:GSTH-4792-MONOMER.
RETL1328306-WGS:GSTH-5716-MONOMER.
SSAP342451:GKFA-774-MONOMER.

Family and domain databases

Gene3Di3.40.309.10. 1 hit.
3.40.605.10. 1 hit.
InterProiIPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR016160. Ald_DH_CS_CYS.
IPR029510. Ald_DH_CS_GLU.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
[Graphical view]
PfamiPF00171. Aldedh. 1 hit.
[Graphical view]
SUPFAMiSSF53720. SSF53720. 1 hit.
PROSITEiPS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Whole genome sequence of Staphylococcus saprophyticus reveals the pathogenesis of uncomplicated urinary tract infection."
    Kuroda M., Yamashita A., Hirakawa H., Kumano M., Morikawa K., Higashide M., Maruyama A., Inose Y., Matoba K., Toh H., Kuhara S., Hattori M., Ohta T.
    Proc. Natl. Acad. Sci. U.S.A. 102:13272-13277(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 15305 / DSM 20229.

Entry informationi

Entry nameiALD1_STAS1
AccessioniPrimary (citable) accession number: Q49Z69
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 10, 2007
Last sequence update: September 13, 2005
Last modified: May 27, 2015
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.