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Q49Z62

- PTPB_STAS1

UniProt

Q49Z62 - PTPB_STAS1

Protein

Low molecular weight protein-tyrosine-phosphatase PtpB

Gene

ptpB

Organism
Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 56 (01 Oct 2014)
      Sequence version 1 (13 Sep 2005)
      Previous versions | rss
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    • Comment

    Functioni

    Dephosphorylates the phosphotyrosine-containing proteins.By similarity

    Catalytic activityi

    Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei7 – 71NucleophileBy similarity
    Active sitei13 – 131By similarity
    Active sitei111 – 1111Proton donorBy similarity

    GO - Molecular functioni

    1. protein tyrosine phosphatase activity Source: UniProtKB-EC

    Keywords - Molecular functioni

    Hydrolase, Protein phosphatase

    Enzyme and pathway databases

    BioCyciSSAP342451:GKFA-781-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Low molecular weight protein-tyrosine-phosphatase PtpB (EC:3.1.3.48)
    Alternative name(s):
    Phosphotyrosine phosphatase B
    Short name:
    PTPase B
    Gene namesi
    Name:ptpB
    Ordered Locus Names:SSP0769
    OrganismiStaphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229)
    Taxonomic identifieri342451 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus
    ProteomesiUP000006371: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 140140Low molecular weight protein-tyrosine-phosphatase PtpBPRO_0000300683Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi342451.SSP0769.

    Structurei

    3D structure databases

    ProteinModelPortaliQ49Z62.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG0394.
    HOGENOMiHOG000273091.
    KOiK01104.
    OMAiPMAMALL.
    OrthoDBiEOG6MH5JB.

    Family and domain databases

    InterProiIPR023485. Ptyr_pPase_SF.
    IPR000106. Tyr_phospatase/Ars_reductase.
    IPR017867. Tyr_phospatase_low_mol_wt.
    [Graphical view]
    PANTHERiPTHR11717. PTHR11717. 1 hit.
    PfamiPF01451. LMWPc. 1 hit.
    [Graphical view]
    PRINTSiPR00719. LMWPTPASE.
    SMARTiSM00226. LMWPc. 1 hit.
    [Graphical view]
    SUPFAMiSSF52788. SSF52788. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q49Z62-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKIIFVCTGN TCRSPMAESI AQSKLPNHTI VSRGMYAIDG QPISDHTKEI    50
    LLERHLNVPY QAQSFTASDI NADLILTMGS SHKRIIKELY DNTDHVFTLN 100
    EYVDKIGEVS DPFGGSKSAY LEIYNELNLL IDSLKNKILN 140
    Length:140
    Mass (Da):15,703
    Last modified:September 13, 2005 - v1
    Checksum:i48B1DB6DA157849D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP008934 Genomic DNA. Translation: BAE17914.1.
    RefSeqiWP_011302672.1. NC_007350.1.
    YP_300859.1. NC_007350.1.

    Genome annotation databases

    EnsemblBacteriaiBAE17914; BAE17914; SSP0769.
    GeneIDi3615834.
    KEGGissp:SSP0769.
    PATRICi19623040. VBIStaSap90642_0771.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP008934 Genomic DNA. Translation: BAE17914.1 .
    RefSeqi WP_011302672.1. NC_007350.1.
    YP_300859.1. NC_007350.1.

    3D structure databases

    ProteinModelPortali Q49Z62.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 342451.SSP0769.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAE17914 ; BAE17914 ; SSP0769 .
    GeneIDi 3615834.
    KEGGi ssp:SSP0769.
    PATRICi 19623040. VBIStaSap90642_0771.

    Phylogenomic databases

    eggNOGi COG0394.
    HOGENOMi HOG000273091.
    KOi K01104.
    OMAi PMAMALL.
    OrthoDBi EOG6MH5JB.

    Enzyme and pathway databases

    BioCyci SSAP342451:GKFA-781-MONOMER.

    Family and domain databases

    InterProi IPR023485. Ptyr_pPase_SF.
    IPR000106. Tyr_phospatase/Ars_reductase.
    IPR017867. Tyr_phospatase_low_mol_wt.
    [Graphical view ]
    PANTHERi PTHR11717. PTHR11717. 1 hit.
    Pfami PF01451. LMWPc. 1 hit.
    [Graphical view ]
    PRINTSi PR00719. LMWPTPASE.
    SMARTi SM00226. LMWPc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52788. SSF52788. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Whole genome sequence of Staphylococcus saprophyticus reveals the pathogenesis of uncomplicated urinary tract infection."
      Kuroda M., Yamashita A., Hirakawa H., Kumano M., Morikawa K., Higashide M., Maruyama A., Inose Y., Matoba K., Toh H., Kuhara S., Hattori M., Ohta T.
      Proc. Natl. Acad. Sci. U.S.A. 102:13272-13277(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 15305 / DSM 20229.

    Entry informationi

    Entry nameiPTPB_STAS1
    AccessioniPrimary (citable) accession number: Q49Z62
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: September 11, 2007
    Last sequence update: September 13, 2005
    Last modified: October 1, 2014
    This is version 56 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3