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Protein

Low molecular weight protein-tyrosine-phosphatase PtpB

Gene

ptpB

Organism
Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Dephosphorylates the phosphotyrosine-containing proteins.By similarity

Catalytic activityi

Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei7NucleophileBy similarity1
Active sitei13By similarity1
Active sitei111Proton donorBy similarity1

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Names & Taxonomyi

Protein namesi
Recommended name:
Low molecular weight protein-tyrosine-phosphatase PtpB (EC:3.1.3.48)
Alternative name(s):
Phosphotyrosine phosphatase B
Short name:
PTPase B
Gene namesi
Name:ptpB
Ordered Locus Names:SSP0769
OrganismiStaphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229)
Taxonomic identifieri342451 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcaceaeStaphylococcus
Proteomesi
  • UP000006371 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003006831 – 140Low molecular weight protein-tyrosine-phosphatase PtpBAdd BLAST140

Interactioni

Protein-protein interaction databases

STRINGi342451.SSP0769.

Structurei

3D structure databases

ProteinModelPortaliQ49Z62.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4107WAU. Bacteria.
COG0394. LUCA.
HOGENOMiHOG000273091.
KOiK01104.
OMAiSIDIYKQ.
OrthoDBiPOG091H07J9.

Family and domain databases

CDDicd00115. LMWPc. 1 hit.
InterProiIPR023485. Ptyr_pPase_SF.
IPR017867. Tyr_phospatase_low_mol_wt.
[Graphical view]
PANTHERiPTHR11717:SF14. PTHR11717:SF14. 1 hit.
PfamiPF01451. LMWPc. 1 hit.
[Graphical view]
PRINTSiPR00719. LMWPTPASE.
SMARTiSM00226. LMWPc. 1 hit.
[Graphical view]
SUPFAMiSSF52788. SSF52788. 1 hit.

Sequencei

Sequence statusi: Complete.

Q49Z62-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKIIFVCTGN TCRSPMAESI AQSKLPNHTI VSRGMYAIDG QPISDHTKEI
60 70 80 90 100
LLERHLNVPY QAQSFTASDI NADLILTMGS SHKRIIKELY DNTDHVFTLN
110 120 130 140
EYVDKIGEVS DPFGGSKSAY LEIYNELNLL IDSLKNKILN
Length:140
Mass (Da):15,703
Last modified:September 13, 2005 - v1
Checksum:i48B1DB6DA157849D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP008934 Genomic DNA. Translation: BAE17914.1.
RefSeqiWP_011302672.1. NC_007350.1.

Genome annotation databases

EnsemblBacteriaiBAE17914; BAE17914; SSP0769.
GeneIDi3615834.
KEGGissp:SSP0769.
PATRICi19623040. VBIStaSap90642_0771.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP008934 Genomic DNA. Translation: BAE17914.1.
RefSeqiWP_011302672.1. NC_007350.1.

3D structure databases

ProteinModelPortaliQ49Z62.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi342451.SSP0769.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAE17914; BAE17914; SSP0769.
GeneIDi3615834.
KEGGissp:SSP0769.
PATRICi19623040. VBIStaSap90642_0771.

Phylogenomic databases

eggNOGiENOG4107WAU. Bacteria.
COG0394. LUCA.
HOGENOMiHOG000273091.
KOiK01104.
OMAiSIDIYKQ.
OrthoDBiPOG091H07J9.

Family and domain databases

CDDicd00115. LMWPc. 1 hit.
InterProiIPR023485. Ptyr_pPase_SF.
IPR017867. Tyr_phospatase_low_mol_wt.
[Graphical view]
PANTHERiPTHR11717:SF14. PTHR11717:SF14. 1 hit.
PfamiPF01451. LMWPc. 1 hit.
[Graphical view]
PRINTSiPR00719. LMWPTPASE.
SMARTiSM00226. LMWPc. 1 hit.
[Graphical view]
SUPFAMiSSF52788. SSF52788. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiPTPB_STAS1
AccessioniPrimary (citable) accession number: Q49Z62
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: September 13, 2005
Last modified: November 2, 2016
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.