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Q49YS6 (PTPA_STAS1) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 54. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Low molecular weight protein-tyrosine-phosphatase PtpA

EC=3.1.3.48
Alternative name(s):
Phosphotyrosine phosphatase A
Short name=PTPase A
Gene names
Name:ptpA
Ordered Locus Names:SSP0912
OrganismStaphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229) [Complete proteome] [HAMAP]
Taxonomic identifier342451 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesStaphylococcus

Protein attributes

Sequence length154 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Dephosphorylates the phosphotyrosine-containing proteins By similarity.

Catalytic activity

Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.

Sequence similarities

Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

Ontologies

Keywords
   Molecular functionHydrolase
Protein phosphatase
   Technical termComplete proteome
Gene Ontology (GO)
   Molecular_functionprotein tyrosine phosphatase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 154154Low molecular weight protein-tyrosine-phosphatase PtpA
PRO_0000300669

Sites

Active site81Nucleophile By similarity
Active site141 By similarity
Active site1201Proton donor By similarity

Sequences

Sequence LengthMass (Da)Tools
Q49YS6 [UniParc].

Last modified September 13, 2005. Version 1.
Checksum: 5FF8F65ED77FD0B0

FASTA15417,544
        10         20         30         40         50         60 
MITVAFVCLG NICRSPMAEA IMRQKLLDRN INDIKVTSRG TGQWNLGEPP HEGTQAILSE 

        70         80         90        100        110        120 
HDIPFDGMIS ELFESNDDFD YIIAMDQSNV DNIKQINPNI KGQLFKLLEF SDMTETDVPD 

       130        140        150 
PYYTNNFEGV YKMVQSSCDN LINFIIKDAN LREE 

« Hide

References

[1]"Whole genome sequence of Staphylococcus saprophyticus reveals the pathogenesis of uncomplicated urinary tract infection."
Kuroda M., Yamashita A., Hirakawa H., Kumano M., Morikawa K., Higashide M., Maruyama A., Inose Y., Matoba K., Toh H., Kuhara S., Hattori M., Ohta T.
Proc. Natl. Acad. Sci. U.S.A. 102:13272-13277(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 15305 / DSM 20229.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP008934 Genomic DNA. Translation: BAE18057.1.
RefSeqYP_301002.1. NC_007350.1.

3D structure databases

ProteinModelPortalQ49YS6.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING342451.SSP0912.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAE18057; BAE18057; SSP0912.
GeneID3616815.
KEGGssp:SSP0912.
PATRIC19623330. VBIStaSap90642_0911.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0394.
HOGENOMHOG000273094.
KOK01104.
OMAGTGSWHV.
OrthoDBEOG6MH5JB.
ProtClustDBCLSK885622.

Enzyme and pathway databases

BioCycSSAP342451:GKFA-931-MONOMER.

Family and domain databases

InterProIPR023485. Ptyr_pPase_SF.
IPR000106. Tyr_phospatase/Ars_reductase.
IPR017867. Tyr_phospatase_low_mol_wt.
[Graphical view]
PANTHERPTHR11717. PTHR11717. 1 hit.
PfamPF01451. LMWPc. 1 hit.
[Graphical view]
PRINTSPR00719. LMWPTPASE.
SMARTSM00226. LMWPc. 1 hit.
[Graphical view]
SUPFAMSSF52788. SSF52788. 1 hit.
ProtoNetSearch...

Entry information

Entry namePTPA_STAS1
AccessionPrimary (citable) accession number: Q49YS6
Entry history
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: September 13, 2005
Last modified: April 16, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families