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Q49YC4 (Q49YC4_STAS1) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 58. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length421 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH. RuleBase RU004446

Cofactor

Binds 1 magnesium or manganese ion per subunit By similarity. RuleBase RU004446

Sequence similarities

Belongs to the isocitrate and isopropylmalate dehydrogenases family. RuleBase RU004443

Sequences

Sequence LengthMass (Da)Tools
Q49YC4 [UniParc].

Last modified September 13, 2005. Version 1.
Checksum: 117EF19CDE7A33C6

FASTA42146,344
        10         20         30         40         50         60 
MAGEKVAKTN EGLTVPNNPI IPFIIGDGIG PDIWKAASRV IDAAVEQAYN GEKKIEWKEV 

        70         80         90        100        110        120 
LAGQKAYDET GEWLPQATLD TIEEYLIAIK GPLTTPIGGG IRSLNVALRQ ELDLFTCLRP 

       130        140        150        160        170        180 
VRWFQGVPSP VKRPEDTDMV IFRENTEDIY AGIEFKEGTP EVKKLIDFLQ DEMGAKNIRF 

       190        200        210        220        230        240 
PETSGIGVKP VSKEGTERLV RAAIQYAVDN NRKSLTLVHK GNIMKFTEGA FKQWGYDVAH 

       250        260        270        280        290        300 
NEFGDKVFTW QQYDEIVEKE GKDKANAAQE QAEKDGKIIV KDSIADIFLQ QILTRPSDHD 

       310        320        330        340        350        360 
VVATMNLNGD YVSDALAAQV GGIGIAPGAN INYETGHAIF EATHGTAPKY ADLNKVNPSS 

       370        380        390        400        410        420 
EILSAVLMLE HLGWQEAADK ITASIEKTIA SKVVTYDFAR LMDGAKEVST SDFADELIKN 


L

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References

[1]"Whole genome sequence of Staphylococcus saprophyticus reveals the pathogenesis of uncomplicated urinary tract infection."
Kuroda M., Yamashita A., Hirakawa H., Kumano M., Morikawa K., Higashide M., Maruyama A., Inose Y., Matoba K., Toh H., Kuhara S., Hattori M., Ohta T.
Proc. Natl. Acad. Sci. U.S.A. 102:13272-13277(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 15305 / DSM 20229.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP008934 Genomic DNA. Translation: BAE18217.1.
RefSeqYP_301162.1. NC_007350.1.

3D structure databases

ProteinModelPortalQ49YC4.
SMRQ49YC4. Positions 3-421.
ModBaseSearch...

Protein-protein interaction databases

STRING342451.SSP1072.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAE18217; BAE18217; SSP1072.
GeneID3615440.
KEGGssp:SSP1072.
PATRIC19623728. VBIStaSap90642_1071.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0538.
HOGENOMHOG000021113.
KOK00031.
OMAFRDWGYE.
ProtClustDBPRK07006.

Family and domain databases

Gene3D3.40.718.10. 1 hit.
InterProIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERPTHR11835. PTHR11835. 1 hit.
PfamPF00180. Iso_dh. 1 hit.
[Graphical view]
TIGRFAMsTIGR00183. prok_nadp_idh. 1 hit.
PROSITEPS00470. IDH_IMDH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ49YC4_STAS1
AccessionPrimary (citable) accession number: Q49YC4
Entry history
Integrated into UniProtKB/TrEMBL: September 13, 2005
Last sequence update: September 13, 2005
Last modified: May 1, 2013
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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