Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Aerobic glycerol-3-phosphate dehydrogenase

Gene

glpD

Organism
Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

sn-glycerol 3-phosphate + a quinone = glycerone phosphate + a quinol.

Cofactori

FADBy similarity

Pathwayi

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi21 – 4929FADSequence AnalysisAdd
BLAST

GO - Molecular functioni

  1. sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity Source: UniProtKB-EC

GO - Biological processi

  1. glycerol-3-phosphate metabolic process Source: InterPro
  2. glycerol catabolic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Glycerol metabolism

Keywords - Ligandi

FAD, Flavoprotein

Enzyme and pathway databases

BioCyciSSAP342451:GKFA-1518-MONOMER.
UniPathwayiUPA00618; UER00674.

Names & Taxonomyi

Protein namesi
Recommended name:
Aerobic glycerol-3-phosphate dehydrogenase (EC:1.1.5.3)
Gene namesi
Name:glpD
Ordered Locus Names:SSP1459
OrganismiStaphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229)
Taxonomic identifieri342451 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus
ProteomesiUP000006371 Componenti: Chromosome

Subcellular locationi

  1. Cytoplasm By similarity

GO - Cellular componenti

  1. glycerol-3-phosphate dehydrogenase complex Source: InterPro
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 557557Aerobic glycerol-3-phosphate dehydrogenasePRO_0000270068Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi342451.SSP1459.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0578.
HOGENOMiHOG000004812.
KOiK00111.
OMAiPVDQQEQ.
OrthoDBiEOG651SR7.

Family and domain databases

InterProiIPR006076. FAD-dep_OxRdtase.
IPR000447. G3P_DH_FAD-dep.
[Graphical view]
PfamiPF01266. DAO. 1 hit.
[Graphical view]
PRINTSiPR01001. FADG3PDH.
PROSITEiPS00977. FAD_G3PDH_1. 1 hit.
PS00978. FAD_G3PDH_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q49X94-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSLSTLKREQ IKKDLKDQEF DVVIIGGGIT GAGIALDASE RGMKVALVEM
60 70 80 90 100
QDFAQGTSSR STKLVHGGLR YLKQLQVGVV AETGRERAIV YENGPHVTTP
110 120 130 140 150
ERMLLPMHKG GSMGKFTTSI GLAMYDRLAG VKKAERKTML NAKETLEKEP
160 170 180 190 200
LVKKAGLKGG GSYVEYRTDD ARLTIEVMKR AEEKGAKVIN HTKSVHFTYD
210 220 230 240 250
SNEKVNGIQV EDQISNETYP IKAKKVINAS GPWVDEVRSG DYARNNKQLR
260 270 280 290 300
LTKGVHIVID QSKFPLGQAV YFDTEKDGRM IFAIPREGKA YVGTTDTFYD
310 320 330 340 350
NNKTSPLANQ EDRDYLIDAI NYMFPDVNVA DEDIESSWAG VRPLILEEGK
360 370 380 390 400
DPSEISRKDE VWEGKSGLLT IAGGKLTGYR HMALEIVDLL SKRLKSEFGL
410 420 430 440 450
KFDKCATKHL TISGGDVGGS ANFDKFIEQK VEEAKSYQID ESTARHFASK
460 470 480 490 500
YGSNAEELFK IAQTAQYQET GLPLDIYTEL VYSIQNEMVY RPTDFFIRRT
510 520 530 540 550
GKLYFKIDDV LNYKEQVIDV MAGLLGYTNI EKEAYTKELQ IAIDEAQTGN

HQPAVKE
Length:557
Mass (Da):62,260
Last modified:September 13, 2005 - v1
Checksum:i519E5CAF87EC8989
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP008934 Genomic DNA. Translation: BAE18604.1.
RefSeqiYP_301549.1. NC_007350.1.

Genome annotation databases

EnsemblBacteriaiBAE18604; BAE18604; SSP1459.
KEGGissp:SSP1459.
PATRICi19624512. VBIStaSap90642_1463.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP008934 Genomic DNA. Translation: BAE18604.1.
RefSeqiYP_301549.1. NC_007350.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi342451.SSP1459.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAE18604; BAE18604; SSP1459.
KEGGissp:SSP1459.
PATRICi19624512. VBIStaSap90642_1463.

Phylogenomic databases

eggNOGiCOG0578.
HOGENOMiHOG000004812.
KOiK00111.
OMAiPVDQQEQ.
OrthoDBiEOG651SR7.

Enzyme and pathway databases

UniPathwayiUPA00618; UER00674.
BioCyciSSAP342451:GKFA-1518-MONOMER.

Family and domain databases

InterProiIPR006076. FAD-dep_OxRdtase.
IPR000447. G3P_DH_FAD-dep.
[Graphical view]
PfamiPF01266. DAO. 1 hit.
[Graphical view]
PRINTSiPR01001. FADG3PDH.
PROSITEiPS00977. FAD_G3PDH_1. 1 hit.
PS00978. FAD_G3PDH_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Whole genome sequence of Staphylococcus saprophyticus reveals the pathogenesis of uncomplicated urinary tract infection."
    Kuroda M., Yamashita A., Hirakawa H., Kumano M., Morikawa K., Higashide M., Maruyama A., Inose Y., Matoba K., Toh H., Kuhara S., Hattori M., Ohta T.
    Proc. Natl. Acad. Sci. U.S.A. 102:13272-13277(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 15305 / DSM 20229.

Entry informationi

Entry nameiGLPD_STAS1
AccessioniPrimary (citable) accession number: Q49X94
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 9, 2007
Last sequence update: September 13, 2005
Last modified: April 1, 2015
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.