Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q49X94 (GLPD_STAS1) Reviewed, UniProtKB/Swiss-Prot

Last modified November 13, 2013. Version 61. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Aerobic glycerol-3-phosphate dehydrogenase

EC=1.1.5.3
Gene names
Name:glpD
Ordered Locus Names:SSP1459
OrganismStaphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229) [Complete proteome] [HAMAP]
Taxonomic identifier342451 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesStaphylococcus

Protein attributes

Sequence length557 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

sn-glycerol 3-phosphate + a quinone = glycerone phosphate + a quinol.

Cofactor

FAD By similarity.

Pathway

Polyol metabolism; glycerol degradation via glycerol kinase pathway; glycerone phosphate from sn-glycerol 3-phosphate (aerobic route): step 1/1.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

Ontologies

Keywords
   Biological processGlycerol metabolism
   Cellular componentCytoplasm
   LigandFAD
Flavoprotein
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglycerol catabolic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

glycerol-3-phosphate metabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular_componentglycerol-3-phosphate dehydrogenase complex

Inferred from electronic annotation. Source: InterPro

   Molecular_functionsn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 557557Aerobic glycerol-3-phosphate dehydrogenase
PRO_0000270068

Regions

Nucleotide binding21 – 4929FAD Potential

Sequences

Sequence LengthMass (Da)Tools
Q49X94 [UniParc].

Last modified September 13, 2005. Version 1.
Checksum: 519E5CAF87EC8989

FASTA55762,260
        10         20         30         40         50         60 
MSLSTLKREQ IKKDLKDQEF DVVIIGGGIT GAGIALDASE RGMKVALVEM QDFAQGTSSR 

        70         80         90        100        110        120 
STKLVHGGLR YLKQLQVGVV AETGRERAIV YENGPHVTTP ERMLLPMHKG GSMGKFTTSI 

       130        140        150        160        170        180 
GLAMYDRLAG VKKAERKTML NAKETLEKEP LVKKAGLKGG GSYVEYRTDD ARLTIEVMKR 

       190        200        210        220        230        240 
AEEKGAKVIN HTKSVHFTYD SNEKVNGIQV EDQISNETYP IKAKKVINAS GPWVDEVRSG 

       250        260        270        280        290        300 
DYARNNKQLR LTKGVHIVID QSKFPLGQAV YFDTEKDGRM IFAIPREGKA YVGTTDTFYD 

       310        320        330        340        350        360 
NNKTSPLANQ EDRDYLIDAI NYMFPDVNVA DEDIESSWAG VRPLILEEGK DPSEISRKDE 

       370        380        390        400        410        420 
VWEGKSGLLT IAGGKLTGYR HMALEIVDLL SKRLKSEFGL KFDKCATKHL TISGGDVGGS 

       430        440        450        460        470        480 
ANFDKFIEQK VEEAKSYQID ESTARHFASK YGSNAEELFK IAQTAQYQET GLPLDIYTEL 

       490        500        510        520        530        540 
VYSIQNEMVY RPTDFFIRRT GKLYFKIDDV LNYKEQVIDV MAGLLGYTNI EKEAYTKELQ 

       550 
IAIDEAQTGN HQPAVKE 

« Hide

References

[1]"Whole genome sequence of Staphylococcus saprophyticus reveals the pathogenesis of uncomplicated urinary tract infection."
Kuroda M., Yamashita A., Hirakawa H., Kumano M., Morikawa K., Higashide M., Maruyama A., Inose Y., Matoba K., Toh H., Kuhara S., Hattori M., Ohta T.
Proc. Natl. Acad. Sci. U.S.A. 102:13272-13277(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 15305 / DSM 20229.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP008934 Genomic DNA. Translation: BAE18604.1.
RefSeqYP_301549.1. NC_007350.1.

3D structure databases

ProteinModelPortalQ49X94.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING342451.SSP1459.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAE18604; BAE18604; SSP1459.
GeneID3615086.
KEGGssp:SSP1459.
PATRIC19624512. VBIStaSap90642_1463.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0578.
HOGENOMHOG000004812.
KOK00111.
OMAPVDQQEQ.
OrthoDBEOG651SR7.
ProtClustDBCLSK872929.

Enzyme and pathway databases

BioCycSSAP342451:GKFA-1518-MONOMER.
UniPathwayUPA00618; UER00674.

Family and domain databases

InterProIPR006076. FAD-dep_OxRdtase.
IPR000447. G3P_DH_FAD-dep.
[Graphical view]
PfamPF01266. DAO. 1 hit.
[Graphical view]
PRINTSPR01001. FADG3PDH.
PROSITEPS00977. FAD_G3PDH_1. 1 hit.
PS00978. FAD_G3PDH_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGLPD_STAS1
AccessionPrimary (citable) accession number: Q49X94
Entry history
Integrated into UniProtKB/Swiss-Prot: January 9, 2007
Last sequence update: September 13, 2005
Last modified: November 13, 2013
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways