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Q49WA1

- G6PI_STAS1

UniProt

Q49WA1 - G6PI_STAS1

Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 61 (01 Oct 2014)
      Sequence version 1 (13 Sep 2005)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei285 – 2851Proton donorUniRule annotation
    Active sitei306 – 3061UniRule annotation
    Active sitei420 – 4201UniRule annotation

    GO - Molecular functioni

    1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. gluconeogenesis Source: UniProtKB-HAMAP
    2. glycolytic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Isomerase

    Keywords - Biological processi

    Gluconeogenesis, Glycolysis

    Enzyme and pathway databases

    BioCyciSSAP342451:GKFA-1875-MONOMER.
    UniPathwayiUPA00109; UER00181.
    UPA00138.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
    Short name:
    GPIUniRule annotation
    Alternative name(s):
    Phosphoglucose isomeraseUniRule annotation
    Short name:
    PGIUniRule annotation
    Phosphohexose isomeraseUniRule annotation
    Short name:
    PHIUniRule annotation
    Gene namesi
    Name:pgiUniRule annotation
    Ordered Locus Names:SSP1813
    OrganismiStaphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229)
    Taxonomic identifieri342451 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus
    ProteomesiUP000006371: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 443443Glucose-6-phosphate isomerasePRO_0000230937Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi342451.SSP1813.

    Structurei

    3D structure databases

    ProteinModelPortaliQ49WA1.
    SMRiQ49WA1. Positions 4-443.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the GPI family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0166.
    HOGENOMiHOG000100403.
    KOiK01810.
    OMAiLANFNPK.
    OrthoDBiEOG64R61J.

    Family and domain databases

    HAMAPiMF_00473. G6P_isomerase.
    InterProiIPR001672. G6P_Isomerase.
    IPR018189. Phosphoglucose_isomerase_CS.
    [Graphical view]
    PANTHERiPTHR11469. PTHR11469. 1 hit.
    PfamiPF00342. PGI. 1 hit.
    [Graphical view]
    PRINTSiPR00662. G6PISOMERASE.
    PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
    PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
    PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q49WA1-1 [UniParc]FASTAAdd to Basket

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    MTHIQLDYGK TLEFFGEHEL QQQKDIVKSI HNTIHKGTGA GSDFLGWIDL    50
    PVDYDKEEFS RILEASKRVK DNSEVFVVIG IGGSYLGARA AIEMLTSSFR 100
    NSDEYPEIVF VGNHLSSTYT QELIDYLDGK DFSVNVISKS GTTTEPAVSF 150
    RLFKQLLENK YGKEEAKKRI FATTDKEKGA LKQLATNEGY ETFVVPDDIG 200
    GRYSVLTAVG LLPIAVAGID IKAMMEGAAK AREELSSENL EDNIAYQYAT 250
    IRNVLYAKGY DTEMLINYEP SMQYFNEWWK QLFGESEGKD YKGIYPSSAN 300
    YTTDLHSLGQ YVQEGRRFLF ETVVKVNNPK HDITIEEDSD NLDGLNYLAG 350
    KTIDEVNTKA FEGTLLAHTD GGVPNIVLNI PRLDEETFGY VVYFFELACS 400
    MSGYQLGVNP FNQPGVEAYK QNMFALLGKQ GFEDKKEALE KRL 443
    Length:443
    Mass (Da):49,796
    Last modified:September 13, 2005 - v1
    Checksum:i69962B29D3BF0FDF
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP008934 Genomic DNA. Translation: BAE18958.1.
    RefSeqiWP_011303508.1. NC_007350.1.
    YP_301903.1. NC_007350.1.

    Genome annotation databases

    EnsemblBacteriaiBAE18958; BAE18958; SSP1813.
    GeneIDi3616468.
    KEGGissp:SSP1813.
    PATRICi19625211. VBIStaSap90642_1809.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP008934 Genomic DNA. Translation: BAE18958.1 .
    RefSeqi WP_011303508.1. NC_007350.1.
    YP_301903.1. NC_007350.1.

    3D structure databases

    ProteinModelPortali Q49WA1.
    SMRi Q49WA1. Positions 4-443.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 342451.SSP1813.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAE18958 ; BAE18958 ; SSP1813 .
    GeneIDi 3616468.
    KEGGi ssp:SSP1813.
    PATRICi 19625211. VBIStaSap90642_1809.

    Phylogenomic databases

    eggNOGi COG0166.
    HOGENOMi HOG000100403.
    KOi K01810.
    OMAi LANFNPK.
    OrthoDBi EOG64R61J.

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00181 .
    UPA00138 .
    BioCyci SSAP342451:GKFA-1875-MONOMER.

    Family and domain databases

    HAMAPi MF_00473. G6P_isomerase.
    InterProi IPR001672. G6P_Isomerase.
    IPR018189. Phosphoglucose_isomerase_CS.
    [Graphical view ]
    PANTHERi PTHR11469. PTHR11469. 1 hit.
    Pfami PF00342. PGI. 1 hit.
    [Graphical view ]
    PRINTSi PR00662. G6PISOMERASE.
    PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
    PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
    PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Whole genome sequence of Staphylococcus saprophyticus reveals the pathogenesis of uncomplicated urinary tract infection."
      Kuroda M., Yamashita A., Hirakawa H., Kumano M., Morikawa K., Higashide M., Maruyama A., Inose Y., Matoba K., Toh H., Kuhara S., Hattori M., Ohta T.
      Proc. Natl. Acad. Sci. U.S.A. 102:13272-13277(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 15305 / DSM 20229.

    Entry informationi

    Entry nameiG6PI_STAS1
    AccessioniPrimary (citable) accession number: Q49WA1
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 4, 2006
    Last sequence update: September 13, 2005
    Last modified: October 1, 2014
    This is version 61 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3