ID   GTAB2_STAS1             Reviewed;         289 AA.
AC   Q49VP4;
DT   23-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT   13-SEP-2005, sequence version 1.
DT   16-JUN-2009, entry version 21.
DE   RecName: Full=UTP--glucose-1-phosphate uridylyltransferase 2;
DE            EC=2.7.7.9;
DE   AltName: Full=UDP-glucose pyrophosphorylase 2;
DE            Short=UDPGP 2;
DE   AltName: Full=Alpha-D-glucosyl-1-phosphate uridylyltransferase 2;
DE   AltName: Full=Uridine diphosphoglucose pyrophosphorylase 2;
GN   Name=gtaB2; OrderedLocusNames=SSP2021;
OS   Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 /
OS   DSM 20229).
OC   Bacteria; Firmicutes; Bacillales; Staphylococcus.
OX   NCBI_TaxID=342451;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16135568; DOI=10.1073/pnas.0502950102;
RA   Kuroda M., Yamashita A., Hirakawa H., Kumano M., Morikawa K.,
RA   Higashide M., Maruyama A., Inose Y., Matoba K., Toh H., Kuhara S.,
RA   Hattori M., Ohta T.;
RT   "Whole genome sequence of Staphylococcus saprophyticus reveals the
RT   pathogenesis of uncomplicated urinary tract infection.";
RL   Proc. Natl. Acad. Sci. U.S.A. 102:13272-13277(2005).
CC   -!- FUNCTION: Catalyzes the formation of UDP-glucose from glucose-1-
CC       phosphate and UTP. This is an intermediate step in the
CC       biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG), i.e. a
CC       glycolipid found in the membrane, which is also used as a membrane
CC       anchor for lipoteichoic acid (LTA) (By similarity).
CC   -!- CATALYTIC ACTIVITY: UTP + alpha-D-glucose 1-phosphate =
CC       diphosphate + UDP-glucose.
CC   -!- PATHWAY: Glycolipid metabolism; diglucosyl-diacylglycerol
CC       biosynthesis.
CC   -!- SIMILARITY: Belongs to the UDPGP type 2 family.
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DR   EMBL; AP008934; BAE19166.1; -; Genomic_DNA.
DR   RefSeq; YP_302111.1; -.
DR   GeneID; 3616735; -.
DR   GenomeReviews; AP008934_GR; SSP2021.
DR   KEGG; ssp:SSP2021; -.
DR   NMPDR; fig|342451.4.peg.2174; -.
DR   HOGENOM; Q49VP4; -.
DR   OMA; Q49VP4; DINICFI.
DR   BioCyc; SSAP342451:SSP2021-MON; -.
DR   GO; GO:0003983; F:UTP:glucose-1-phosphate uridylyltransferase...; IEA:EC.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   GO; GO:0006011; P:UDP-glucose metabolic process; IEA:InterPro.
DR   InterPro; IPR005771; GalU_trans_bac.
DR   InterPro; IPR005835; NTP_transferase.
DR   Pfam; PF00483; NTP_transferase; 1.
DR   TIGRFAMs; TIGR01099; galU; 1.
PE   3: Inferred from homology;
KW   Carbohydrate metabolism; Complete proteome; Nucleotidyltransferase;
KW   Transferase.
FT   CHAIN         1    289       UTP--glucose-1-phosphate
FT                                uridylyltransferase 2.
FT                                /FTId=PRO_0000308314.
SQ   SEQUENCE   289 AA;  32658 MW;  D8140ABBCCAEB036 CRC64;
     MRKIKKAIIP AAGLGTRFLP ATKAMPKEML PILDKPTIQY IVEEAARAGI EDIIIVTGKH
     KRAIEDHFDN QKELEMILQE KGKTDLLEKV KYSTELANIF YVRQKEQKGL GHAIYSARQF
     IGDEPFAVLL GDDIVESDNP AIKQLIEAYE ETGKSVIGVQ EVDEAQTHRY GIIDPLQKFG
     RKYEVNEFVE KPKQGTAPSN LAIMGRYVLT PDIFDYLATQ GEGAGGEIQL TDAIERLNRA
     DQVYAYDFEG DRYDVGEKLG FVKTTIEYAL KDESMHDELV EFIKKLKLN
//