Q49V22 (Q49V22_STAS1) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Cysteine synthase RuleBase RU003985
EC=2.5.1.47 RuleBase RU003985

Gene names

Ordered Locus Names:

SSP2243

Organism

Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229) [Complete proteome] [HAMAP]

Taxonomic identifier

342451 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Staphylococcus

Protein attributes

Sequence length	310 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	O(3)-acetyl-L-serine + H2S = L-cysteine + acetate. RuleBase RU003985
Sequence similarities	Belongs to the cysteine synthase/cystathionine beta-synthase family. RuleBase RU003985

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Cysteine biosynthesis RuleBase RU003985
Molecular function	Transferase RuleBase RU003985
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	cysteine biosynthetic process from serine Inferred from electronic annotation. Source: InterPro
Molecular function	cysteine synthase activity Inferred from electronic annotation. Source: EC pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro transferase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q49V22 [UniParc]. Last modified September 13, 2005. Version 1. Checksum: D295390D93F010AF	FASTA	310	33,053
	10 20 30 40 50 60 MTNKPVDNIV EVIGNTPVVK LNKVVDEDIA DVYVKLEYQN PGGSVKDRIA LAMIEEAEKA 70 80 90 100 110 120 GKIKPGDTIV EPTSGNTGIG LAFVCAAKGY KAVFTMPETM SQERRNLLKA YGAELVLTPG 130 140 150 160 170 180 SEAMKGAIKK AKELKEEHGY YEPQQFENPA NPRVHELTTG PELVQQFEGK TIDSFLAGVG 190 200 210 220 230 240 TGGTLSGAGK VLKENYPDIN LVAIEPEDSP VLSGGEPGPH KLQGLGAGFI PDTLDENIYD 250 260 270 280 290 300 EVVQVGNETA MDMARKVAKE EGILCGISSG AAIYAAIEKA KQLGKGKTVV TVLPSNGERY 310 LSTPLFAFDD

References

[1]

"Whole genome sequence of Staphylococcus saprophyticus reveals the pathogenesis of uncomplicated urinary tract infection." Kuroda M., Yamashita A., Hirakawa H., Kumano M., Morikawa K., Higashide M., Maruyama A., Inose Y., Matoba K., Toh H., Kuhara S., Hattori M., Ohta T. Proc. Natl. Acad. Sci. U.S.A. 102:13272-13277(2005) [PubMed: 16135568] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP008934 Genomic DNA. Translation: BAE19388.1.
RefSeq	YP_302333.1. NC_007350.1.
3D structure databases
ProteinModelPortal	Q49V22.
SMR	Q49V22. Positions 4-310.
ModBase	Search...
Protein-protein interaction databases
STRING	Q49V22.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBSTAT00000047333; EBSTAP00000045702; EBSTAG00000047330.
GeneID	3615573.
GenomeReviews	Gene locus SSP2243 in contig AP008934_GR.
KEGG	ssp:SSP2243.
NMPDR	fig|342451.4.peg.2059.
PATRIC	19626095. VBIStaSap90642_2234.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0031.
GeneTree	EBGT00050000024422.
HOGENOM	HBG748215.
OMA	SAGANIH.
PhylomeDB	Q49V22.
ProtClustDB	CLSK884704.
Enzyme and pathway databases
BioCyc	SSAP342451:SSP2243-MONOMER.
Family and domain databases
InterPro	IPR001216. Cys_synth_BS. IPR005856. Cys_synthKM. IPR005859. CysK. IPR001926. PyrdxlP-dep_enz_bsu. [Graphical view]
KO	K01738.
Pfam	PF00291. PALP. 1 hit. [Graphical view]
SUPFAM	SSF53686. PyrdxlP-dep_enz_bsu. 1 hit.
TIGRFAMs	TIGR01139. CysK. 1 hit. TIGR01136. CysKM. 1 hit.
PROSITE	PS00901. CYS_SYNTHASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q49V22_STAS1

Accession

Primary (citable) accession number: Q49V22

Entry history

Integrated into UniProtKB/TrEMBL:	September 13, 2005
Last sequence update:	September 13, 2005
Last modified:	December 14, 2011
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)