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Q49UX4 (SLE1_STAS1) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 59. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
N-acetylmuramoyl-L-alanine amidase sle1

EC=3.5.1.28
Gene names
Name:sle1
Synonyms:aaa
Ordered Locus Names:SSP2291
OrganismStaphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229) [Complete proteome] [HAMAP]
Taxonomic identifier342451 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesStaphylococcus

Protein attributes

Sequence length327 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Function

Peptidoglycan hydrolase involved in the splitting of the septum during cell division By similarity.

Catalytic activity

Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides.

Subcellular location

Secreted By similarity. Cell surface By similarity.

Sequence similarities

Contains 3 LysM repeats.

Contains 1 peptidase C51 domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2525 Potential
Chain26 – 327302N-acetylmuramoyl-L-alanine amidase sle1
PRO_0000231630

Regions

Repeat29 – 7143LysM 1
Repeat88 – 13043LysM 2
Repeat152 – 19443LysM 3
Domain203 – 327125Peptidase C51

Sequences

Sequence LengthMass (Da)Tools
Q49UX4 [UniParc].

Last modified September 13, 2005. Version 1.
Checksum: 32B7759C57878F5A

FASTA32734,491
        10         20         30         40         50         60 
MRKKIIATVI GTSALAAVTW TNADAATTYK VKSGDSLWSI ANKYNMSVAK LKSLNNLTSN 

        70         80         90        100        110        120 
VIFPNQSLKV SGSTSSSTSS NTSTGSTYTV KSGDTLSGIA AKYGTTYQKI MSLNGLSNFN 

       130        140        150        160        170        180 
IYPGQKLKVS GAASSSSSNT SGNTSSGSTT TYTVKSGDSL SAIAAKYGTT YQKIMSLNGL 

       190        200        210        220        230        240 
TNFNIYPGQK LKVSGKASTG GSGSSSTGSA GYKTPVFNHS NLYDWGQCTW HVFNKRAQIG 

       250        260        270        280        290        300 
KGISTYWWNA NNWDTAAAAD GYTIDRKATV GSILQSDMGY YGHVAFVESV NANGSITISE 

       310        320 
MNYSASPGIV TYRTIPASQV SSYVYIH 

« Hide

References

[1]"Whole genome sequence of Staphylococcus saprophyticus reveals the pathogenesis of uncomplicated urinary tract infection."
Kuroda M., Yamashita A., Hirakawa H., Kumano M., Morikawa K., Higashide M., Maruyama A., Inose Y., Matoba K., Toh H., Kuhara S., Hattori M., Ohta T.
Proc. Natl. Acad. Sci. U.S.A. 102:13272-13277(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 15305 / DSM 20229.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP008934 Genomic DNA. Translation: BAE19436.1.
RefSeqYP_302381.1. NC_007350.1.

3D structure databases

ProteinModelPortalQ49UX4.
SMRQ49UX4. Positions 214-327.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING342451.SSP2291.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAE19436; BAE19436; SSP2291.
GeneID3615679.
KEGGssp:SSP2291.
PATRIC19626199. VBIStaSap90642_2282.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG3942.
HOGENOMHOG000279823.
OMAEMNYSAS.
OrthoDBEOG6GTZPF.
ProtClustDBCLSK884669.

Enzyme and pathway databases

BioCycSSAP342451:GKFA-2375-MONOMER.

Family and domain databases

Gene3D3.10.350.10. 3 hits.
InterProIPR007921. CHAP_dom.
IPR018392. LysM_dom.
[Graphical view]
PfamPF05257. CHAP. 1 hit.
PF01476. LysM. 3 hits.
[Graphical view]
SMARTSM00257. LysM. 3 hits.
[Graphical view]
SUPFAMSSF54106. SSF54106. 3 hits.
PROSITEPS50911. CHAP. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSLE1_STAS1
AccessionPrimary (citable) accession number: Q49UX4
Entry history
Integrated into UniProtKB/Swiss-Prot: April 4, 2006
Last sequence update: September 13, 2005
Last modified: April 16, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Peptidase families

Classification of peptidase families and list of entries