Skip Header

Contribute Send feedback
Read comments (?) or add your own

Q49PX0 (Q49PX0_9POXV) Unreviewed, UniProtKB/TrEMBL

Last modified May 29, 2013. Version 39. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesSubmitted name:
N1L EMBL AAL57605.1
Submitted name:
N1L protein EMBL AAL48257.1
Submitted name:
Putative virulence factor EMBL AGB75748.1
Submitted name:
VACV-DUKE-037 EMBL ABD98499.1
Submitted name:
VACV026 EMBL ABD57558.1
Submitted name:
Virokine EMBL AAQ93123.1
Gene names
Name:N1L EMBL AGB75748.1
ORF Names:List025 EMBL ABD52475.1, m8028L EMBL AAW23421.1, mO028L EMBL AAW23703.1, VAC_DPP10_037 EMBL AEY72835.1, VAC_DPP11_037 EMBL AEY73072.1, VAC_DPP12_037 EMBL AEY73312.1, VAC_DPP13_037 EMBL AEY73553.1, VAC_DPP15_037 EMBL AEY73784.1, VAC_DPP16_037 EMBL AEY74022.1, VAC_DPP17_037 EMBL AEY74262.1, VAC_DPP19_037 EMBL AEY74491.1, VAC_DPP20_037 EMBL AEY74731.1, VAC_DPP21_037 EMBL AEY74972.1, VAC_DPP9_037 EMBL AEY72597.1, VACAC2_037 EMBL AAR17871.1, VACCL3_037 EMBL AAQ93123.1, VACV-DUKE-037 EMBL ABD98499.1, VACV_026 EMBL ABD57558.1
OrganismVaccinia virus EMBL AAW23703.1
Taxonomic identifier10245 [NCBI]
Taxonomic lineageViruses › dsDNA viruses, no RNA stage › Poxviridae › Chordopoxvirinae › Orthopoxvirus

Protein attributes

Sequence length117 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

Ontologies

Keywords
   Technical term3D-structure PDB 4BBB PDB 4BBC PDB 4BBD PDB 2UXE
Gene Ontology (GO)
None. [Check GOA]

Sequences

Sequence LengthMass (Da)Tools
Q49PX0 [UniParc].

Last modified April 18, 2006. Version 1.
Checksum: 9050C1FECEB1B90B

FASTA11713,962
        10         20         30         40         50         60 
MRTLLIRYIL WRNDNDQTYY NDDFKKLMLL DELVDDGDVC TLIKNMRMTL SDGPLLDRLN 

        70         80         90        100        110 
QPVNNIEDAK RMIAISAKVA RDIGERSEIR WEESFTILFR MIETYFDDLM IDLYGEK

« Hide

References

[1]Bartlett N.W., Smith G.L.
Submitted (NOV-2001) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: WR EMBL AAL48257.1.
[2]Bartlett N.W., Smith G.L.
Submitted (DEC-2001) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: King Institute EMBL AAL57607.1, Lister EMBL AAL57606.1, USSR EMBL AAL57608.1 and Wyeth EMBL AAL57605.1.
[3]"The vaccinia virus N1L protein is an intracellular homodimer that promotes virulence."
Bartlett N., Symons J.A., Tscharke D.C., Smith G.L.
J. Gen. Virol. 83:1965-1976(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: King Institute EMBL AAL57607.1, Lister EMBL AAL57606.1, USSR EMBL AAL57608.1, WR EMBL AAL48257.1 and Wyeth EMBL AAL57605.1.
[4]"An attenuated LC16m8 smallpox vaccine: analysis of full-genome sequence and induction of immune protection."
Morikawa S., Sakiyama T., Hasegawa H., Saijo M., Maeda A., Kurane I., Maeno G., Kimura J., Hirama C., Yoshida T., Asahi-Ozaki Y., Sata T., Kurata T., Kojima A.
J. Virol. 79:11873-11891(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: LC16m8 EMBL AAW23421.1 and LC16mO EMBL AAW23703.1.
[5]"Genomic sequence and analysis of a vaccinia virus isolate from a patient with a smallpox vaccine-related complication."
Li G., Chen N., Feng Z., Buller R.M., Osborne J., Harms T., Damon I., Upton C., Esteban D.J.
Virol. J. 3:88-88(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: DUKE EMBL ABD98499.1.
[6]Wilson R.K., Clifton S.W., Storch G., Bhonagiri V., Pepin K.H., Stanley S., Fulton L., Nash W., Maupin R., Godfrey J., Delehaunty K., Latreille P., Wang C., Kohlberg S., Newman F.K., Frey S.E., Belshe R.B.
Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: 3737 EMBL ABD57558.1.
[7]"Functional and structural studies of the vaccinia virus virulence factor N1 reveal a Bcl-2-like anti-apoptotic protein."
Cooray S., Bahar M.W., Abrescia N.G., McVey C.E., Bartlett N.W., Chen R.A., Stuart D.I., Grimes J.M., Smith G.L.
J. Gen. Virol. 88:1656-1666(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.90 ANGSTROMS).
[8]"Genomic sequence of a clonal isolate of the vaccinia virus Lister strain employed for smallpox vaccination in France and its comparison to other orthopoxviruses."
Garcel A., Crance J.M., Drillien R., Garin D., Favier A.L.
J. Gen. Virol. 88:1906-1916(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: Lister EMBL ABD52475.1.
[9]"Genomic differences of Vaccinia virus clones from Dryvax smallpox vaccine: the Dryvax-like ACAM2000 and the mouse neurovirulent Clone-3."
Osborne J.D., Da Silva M., Frace A.M., Sammons S.A., Olsen-Rasmussen M., Upton C., Buller R.M., Chen N., Feng Z., Roper R.L., Liu J., Pougatcheva S., Chen W., Wohlhueter R.M., Esposito J.J.
Vaccine 25:8807-8832(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: Acambis EMBL AAQ93123.1.
[10]"N1L gene from Vaccinia virus strain IOC."
Reis S.A., Moussatche N., Damaso C.R.A.
Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: IOC EMBL ABP97444.1.
[11]"Genomic analysis of the vaccinia virus strain variants found in Dryvax vaccine."
Qin L., Upton C., Hazes B., Evans D.H.
J. Virol. 85:13049-13060(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: Dryvax EMBL AEY72597.1.
[12]"Comparison of host cell gene expression in cowpox, monkeypox or vaccinia virus-infected cells reveals virus-specific regulation of immune response genes."
Bourquain D., Dabrowski P.W., Nitsche A.
Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: IHD-W EMBL AGB75748.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AF451287 Genomic DNA. Translation: AAL48257.1.
AF455803 Genomic DNA. Translation: AAL57605.1.
AF455804 Genomic DNA. Translation: AAL57606.1.
AF455805 Genomic DNA. Translation: AAL57607.1.
AF455806 Genomic DNA. Translation: AAL57608.1.
AY313848 Genomic DNA. Translation: AAQ93123.1.
AY313847 Genomic DNA. Translation: AAR17871.1.
AY678275 Genomic DNA. Translation: AAW23421.1.
AY678277 Genomic DNA. Translation: AAW23703.1.
DQ121394 Genomic DNA. Translation: ABD52475.1.
DQ377945 Genomic DNA. Translation: ABD57558.1.
DQ439815 Genomic DNA. Translation: ABD98499.1.
EF488967 Genomic DNA. Translation: ABP97444.1.
JN654976 Genomic DNA. Translation: AEY72597.1.
JN654977 Genomic DNA. Translation: AEY72835.1.
JN654978 Genomic DNA. Translation: AEY73072.1.
JN654979 Genomic DNA. Translation: AEY73312.1.
JN654980 Genomic DNA. Translation: AEY73553.1.
JN654981 Genomic DNA. Translation: AEY73784.1.
JN654982 Genomic DNA. Translation: AEY74022.1.
JN654983 Genomic DNA. Translation: AEY74262.1.
JN654984 Genomic DNA. Translation: AEY74491.1.
JN654985 Genomic DNA. Translation: AEY74731.1.
JN654986 Genomic DNA. Translation: AEY74972.1.
KC201194 Genomic DNA. Translation: AGB75748.1.
RefSeqYP_232910.1. NC_006998.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
2UXEX-ray2.90A/B/C/D/E/F1-117[»]
SMRQ49PX0. Positions 1-116.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3707643.

Phylogenomic databases

ProtClustDBPHA2920.

Family and domain databases

InterProIPR009353. Orthopox_N1.
IPR022819. Poxvirus.
[Graphical view]
PfamPF06227. Poxvirus. 1 hit.
[Graphical view]
PIRSFPIRSF003784. VAC_N1L. 1 hit.
ProDomPD015763. Orthopox_N1. 1 hit.
[Graphical view] [Entries sharing at least one domain]
ProtoNetSearch...

Other

ChEMBLCHEMBL1075128.
EvolutionaryTraceQ49PX0.

Entry information

Entry nameQ49PX0_9POXV
AccessionPrimary (citable) accession number: Q49PX0
Entry history
Integrated into UniProtKB/TrEMBL: April 18, 2006
Last sequence update: April 18, 2006
Last modified: May 29, 2013
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·Ontologies·Sequences·References·Cross-refs·Entry info