Q49NQ7 (Q49NQ7_MUSSP) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Melanocortin 4 receptor EMBL AAV92657.1

Gene names

Name:

Mc4r EMBL AAV92657.1

Organism

Mus spretus (Western Mediterranean mouse) (Algerian mouse) EMBL AAV92657.1

Taxonomic identifier

10096 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	332 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Subcellular location	Cell membrane; Multi-pass membrane protein By similarity SAAS SAAS001671.
Sequence similarities	Belongs to the G-protein coupled receptor 1 family. RuleBase RU000688

Ontologies

Keywords
Cellular component	Cell membrane SAAS SAAS001671 Membrane
Domain	Transmembrane Transmembrane helix SAAS SAAS001671
Molecular function	G-protein coupled receptor RuleBase RU000688 SAAS SAAS001671 Receptor Transducer
Gene Ontology (GO)
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	melanocortin receptor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q49NQ7 [UniParc]. Last modified September 13, 2005. Version 1. Checksum: BAD7018E30CF4FC1	FASTA	332	36,959
	10 20 30 40 50 60 MNSTHHHGMY TSLHLWNRSS YGLHGNASES LGKGHPDGGC YEQLFVSPEV FVTLGVISLL 70 80 90 100 110 120 ENILVIVAIA KNKNLHSPMY FFICSLAVAD MLVSVSNGSE TIVITLLNST DTDAQSFTVN 130 140 150 160 170 180 IDNVIDSVIC SSLLASICSL LSIAVDRYFT IFYALQYHNI MTVRRVGIII SCIWAACTVS 190 200 210 220 230 240 GVLFIIYSDS SAVIICLISM FFTMLVLMAS LYVHMFLMAR LHIKRIAVLP GTGTIRQGTN 250 260 270 280 290 300 MKGAITLTIL IGVFVVCWAP FFLHLLFYIS CPQNPYCVCF MSHFNLYLIL IMCNAVIDPL 310 320 330 IYALRSQELR KTFKEIICFY PLGGICELSS RY

References

[1]	"Analysis of Mc4r locus in DIO and DR mice." Reichwald K., Petz U., Klingenspor M., Platzer M. Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: SPRET/Ei EMBL AAV92657.1. Tissue: Spleen EMBL AAV92657.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AY684821 Genomic DNA. Translation: AAV92657.1.
3D structure databases
ProteinModelPortal	Q49NQ7.
SMR	Q49NQ7. Positions 46-320.
ModBase	Search...
Protein family/group databases
GPCRDB	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
HOVERGEN	HBG108148.
Family and domain databases
InterPro	IPR000276. 7TM_GPCR_Rhodpsn. IPR017452. GPCR_Rhodpsn_supfam. IPR000155. Mcort_rcpt_4. IPR001908. Melancort_rcpt. IPR001671. Melcrt_ACTH_rcpt. [Graphical view]
Pfam	PF00001. 7tm_1. 1 hit. [Graphical view]
PRINTS	PR00237. GPCRRHODOPSN. PR00534. MCRFAMILY. PR00535. MELNOCORTINR. PR01062. MELNOCORTN4R.
PROSITE	PS00237. G_PROTEIN_RECEP_F1_1. 1 hit. PS50262. G_PROTEIN_RECEP_F1_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q49NQ7_MUSSP

Accession

Primary (citable) accession number: Q49NQ7

Entry history

Integrated into UniProtKB/TrEMBL:	September 13, 2005
Last sequence update:	September 13, 2005
Last modified:	November 16, 2011
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)