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Protein

Membrane transport protein XK

Gene

XK

Organism
Pan troglodytes (Chimpanzee)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

May be involved in sodium-dependent transport of neutral amino acids or oligopeptides.By similarity

GO - Biological processi

Keywordsi

Biological processAmino-acid transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Membrane transport protein XK
Alternative name(s):
XK-related protein 1
Gene namesi
Name:XK
Synonyms:XKR1, XRG1
OrganismiPan troglodytes (Chimpanzee)
Taxonomic identifieri9598 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePan
Proteomesi
  • UP000002277 Componenti: Unplaced

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 2CytoplasmicSequence analysis2
Transmembranei3 – 23HelicalSequence analysisAdd BLAST21
Topological domaini24 – 37ExtracellularSequence analysisAdd BLAST14
Transmembranei38 – 58HelicalSequence analysisAdd BLAST21
Topological domaini59 – 68CytoplasmicSequence analysis10
Transmembranei69 – 89HelicalSequence analysisAdd BLAST21
Topological domaini90 – 140ExtracellularSequence analysisAdd BLAST51
Transmembranei141 – 161HelicalSequence analysisAdd BLAST21
Topological domaini162 – 171CytoplasmicSequence analysis10
Transmembranei172 – 192HelicalSequence analysisAdd BLAST21
Topological domaini193 – 208ExtracellularSequence analysisAdd BLAST16
Transmembranei209 – 229HelicalSequence analysisAdd BLAST21
Topological domaini230 – 235CytoplasmicSequence analysis6
Transmembranei236 – 256HelicalSequence analysisAdd BLAST21
Topological domaini257 – 277ExtracellularSequence analysisAdd BLAST21
Transmembranei278 – 298HelicalSequence analysisAdd BLAST21
Topological domaini299 – 317CytoplasmicSequence analysisAdd BLAST19
Transmembranei318 – 338HelicalSequence analysisAdd BLAST21
Topological domaini339 – 349ExtracellularSequence analysisAdd BLAST11
Transmembranei350 – 370HelicalSequence analysisAdd BLAST21
Topological domaini371 – 444CytoplasmicSequence analysisAdd BLAST74

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001907691 – 444Membrane transport protein XKAdd BLAST444

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei115PhosphoserineBy similarity1
Disulfide bondi347Interchain (with C-72 in Kell)By similarity

Keywords - PTMi

Disulfide bond, Phosphoprotein

Proteomic databases

PaxDbiQ49LS5.

Interactioni

Protein-protein interaction databases

STRINGi9598.ENSPTRP00000054870.

Family & Domainsi

Sequence similaritiesi

Belongs to the XK family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410IE7C. Eukaryota.
ENOG410XP4P. LUCA.
HOGENOMiHOG000118070.
HOVERGENiHBG055838.
InParanoidiQ49LS5.
KOiK19522.

Family and domain databases

InterProiView protein in InterPro
IPR018629. XK-rel.
PfamiView protein in Pfam
PF09815. XK-related. 1 hit.

Sequencei

Sequence statusi: Complete.

Q49LS5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKFPASVLAS VFLFVAETTA ALSLSSTYRS GGDRMWQALT LLFSLLPCAL
60 70 80 90 100
VQLTLFFVHR DLSRDRPLVL LLHLLQLGPL FRCFEVFCIY FQSGNNEEPY
110 120 130 140 150
VSITKKRQMP KNGLSEEIEK EVGQAEGKLI THRSAFSRAS VIQAFLGSAP
160 170 180 190 200
QLTLQLYISV MQQDVTVGRS LLMTISLLSI VYGALRCNIL AIKIKYDEYE
210 220 230 240 250
VKVKPLAYVC IFLWRSFEIA TRVVVLVLFT SVLKTWVVVI ILINFFSFFL
260 270 280 290 300
YPWILFWCSG SPFPENIEKA LSRVGTTIVL CFLTLLYTGI NMFCWSAVQL
310 320 330 340 350
KIDSPDLISK SHNWYQLLVY YMIRFIENAI LLLLWYLFKT DIYMYVCAPL
360 370 380 390 400
LVLQLLIGYC TAILFMLVFY QFFHPCKKLF SSSVSEGFQR WLRCFCWACR
410 420 430 440
QQKPCEPIGK EDLQSSRDRD ETPSSSKTSP EPGQFLNAED LCSA
Length:444
Mass (Da):50,936
Last modified:September 13, 2005 - v1
Checksum:i6D921D799DD66D98
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY702904 mRNA. Translation: AAV83780.1.
RefSeqiNP_001073390.1. NM_001079921.1.
UniGeneiPtr.6168.

Genome annotation databases

GeneIDi473563.
KEGGiptr:473563.

Similar proteinsi

Entry informationi

Entry nameiXK_PANTR
AccessioniPrimary (citable) accession number: Q49LS5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 11, 2005
Last sequence update: September 13, 2005
Last modified: July 5, 2017
This is version 56 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families