ID   MHPF_PSEPU              Reviewed;         312 AA.
AC   Q49KG0;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   13-SEP-2005, sequence version 1.
DT   16-JUN-2009, entry version 19.
DE   RecName: Full=Acetaldehyde dehydrogenase;
DE            EC=1.2.1.10;
DE   AltName: Full=Acetaldehyde dehydrogenase [acetylating];
GN   Name=mhpF1; Synonyms=cbzQ;
OS   Pseudomonas putida.
OG   Plasmid pKW1.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=303;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=GJ31;
RA   Reineke W., Kunze M.;
RT   "GJ31 meta-operon.";
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Catalyzes the terminal reaction in meta-cleavage
CC       pathways, that is, the transformation of acetaldehyde into acetyl
CC       coenzyme A (By similarity).
CC   -!- CATALYTIC ACTIVITY: Acetaldehyde + CoA + NAD(+) = acetyl-CoA +
CC       NADH.
CC   -!- PATHWAY: Aromatic compound metabolism; 3-phenylpropionic acid
CC       degradation.
CC   -!- SIMILARITY: Belongs to the acetaldehyde dehydrogenase family. MhpF
CC       subfamily.
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DR   EMBL; AY831461; AAX50131.1; -; Genomic_DNA.
DR   SMR; Q49KG0; 1-312.
DR   GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR   GO; GO:0008774; F:acetaldehyde dehydrogenase (acetylating) ac...; IEA:HAMAP.
DR   GO; GO:0051287; F:NAD or NADH binding; IEA:InterPro.
DR   GO; GO:0006520; P:amino acid metabolic process; IEA:InterPro.
DR   GO; GO:0019439; P:aromatic compound catabolic process; IEA:HAMAP.
DR   GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
DR   HAMAP; MF_01657; -; 1.
DR   InterPro; IPR003361; Acetaldehyde_dehydrogenase.
DR   InterPro; IPR015426; Acetylaldehyde_DH_C.
DR   InterPro; IPR000534; Semialdehyde_DH_NAD-bd.
DR   PANTHER; PTHR21123; Acetylald_dh; 1.
DR   Pfam; PF09290; AcetDehyd-dimer; 1.
DR   Pfam; PF01118; Semialdhyde_dh; 1.
DR   PIRSF; PIRSF015689; Actaldh_dh_actl; 1.
DR   TIGRFAMs; TIGR03215; ac_ald_DH_ac; 1.
PE   3: Inferred from homology;
KW   Aromatic hydrocarbons catabolism; NAD; Oxidoreductase; Plasmid.
FT   CHAIN         1    312       Acetaldehyde dehydrogenase.
FT                                /FTId=PRO_0000337983.
SQ   SEQUENCE   312 AA;  32710 MW;  51B57FFE9CF24B43 CRC64;
     MTTKRKVAIV GSGNVGTDLM IKILRNAEHL EMAVMVGIDP ASDGLARAGR MGVATTHEGV
     AGLVKMPEFA DVDFVFDATS AGAHVKNDAL LRATKPGIRV IDLTPAAIGP YCVPVVNLEQ
     HVNAENLNMV TCGGQATIPM VAAVSRVAKV HYAEIVASIA SKSAGPGTRA NIDEFTETTS
     KAIEAIGGAA KGKAIIIMNP AEPPLMMRDT VYVLSEAADQ DHVEASIEEM VAAVNAYVPG
     YRLKQKVQFE VIPDTAPLNI PGHGEFSGLK TSVFIEVEGA AHYLPAYAGN LDIMTSAALA
     TAERMAQSMS QA
//