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Protein
Submitted name:

Envelope glycoprotein

Gene

env

Organism
Human immunodeficiency virus 1
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Keywordsi

Biological processFusion of virus membrane with host membraneSAAS annotation, Host-virus interaction, Viral attachment to host cellSAAS annotation, Viral penetration into host cytoplasm, Virus entry into host cell

Names & Taxonomyi

Protein namesi
Submitted name:
Envelope glycoproteinImported
Gene namesi
Name:envImported
OrganismiHuman immunodeficiency virus 1Imported
Taxonomic identifieri11676 [NCBI]
Taxonomic lineageiVirusesRetro-transcribing virusesRetroviridaeOrthoretrovirinaeLentivirusPrimate lentivirus group
Virus hostiHomo sapiens (Human) [TaxID: 9606]

Subcellular locationi

  • Virion membrane SAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

MembraneSAAS annotation, Viral envelope proteinImported, Virion

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi25 ↔ 58Combined sources
Disulfide bondi103 ↔ 158Combined sources
Disulfide bondi110 ↔ 131Combined sources

Keywords - PTMi

Disulfide bondSAAS annotation

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2NXYX-ray2.00A1-205[»]
SMRiQ49DS8.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ49DS8.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini9 – 208GP120InterPro annotationAdd BLAST200

Family and domain databases

InterProiView protein in InterPro
IPR000777. HIV1_GP160.
PfamiView protein in Pfam
PF00516. GP120. 1 hit.
SUPFAMiSSF56502. SSF56502. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q49DS8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
IRSENITNNA KIIIVQLNES VIINCTRPYN NTRRSTHVGP GQALFTTEII
60 70 80 90 100
GDIRQAHCNI SGTSWNKTLQ QVTAKLKNLF NKTIVFKSPS GGDPEITTHS
110 120 130 140 150
FNCGGEFFYC NTTNLFNNRE TVNNRTITLP CRIKQIINMW QGVGKAMYAP
160 170 180 190 200
PIAGRINCSS NITGLLLTRD GGNGSQQNET FRPGGGDMRD NWRSELYKYK

VVKIEPLG
Length:208
Mass (Da):23,212
Last modified:September 13, 2005 - v1
Checksum:iEEEDDE925D7E6C39
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei208Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY932129 Genomic DNA. Translation: AAY20506.1.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiQ49DS8_9HIV1
AccessioniPrimary (citable) accession number: Q49DS8
Entry historyiIntegrated into UniProtKB/TrEMBL: September 13, 2005
Last sequence update: September 13, 2005
Last modified: July 5, 2017
This is version 67 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources