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Q49DS8

- Q49DS8_9HIV1

UniProt

Q49DS8 - Q49DS8_9HIV1

Protein
Submitted name:

Envelope glycoprotein

Gene

env

Organism
Human immunodeficiency virus 1
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 48 (01 Oct 2014)
      Sequence version 1 (13 Sep 2005)
      Previous versions | rss
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    Functioni

    GO - Biological processi

    1. membrane fusion involved in viral entry into host cell Source: UniProtKB-KW
    2. virion attachment to host cell Source: UniProtKB-KW

    Keywords - Biological processi

    Fusion of virus membrane with host membraneSAAS annotation, Host-virus interaction, Viral attachment to host cellSAAS annotation, Viral penetration into host cytoplasm, Virus entry into host cell

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Envelope glycoproteinImported
    Gene namesi
    Name:envImported
    OrganismiHuman immunodeficiency virus 1Imported
    Taxonomic identifieri11676 [NCBI]
    Taxonomic lineageiVirusesRetro-transcribing virusesRetroviridaeOrthoretrovirinaeLentivirusPrimate lentivirus group
    Virus hostiHomo sapiens (Human) [TaxID: 9606]

    Subcellular locationi

    GO - Cellular componenti

    1. viral envelope Source: UniProtKB-KW

    Keywords - Cellular componenti

    Viral envelope proteinImported, Virion

    PTM / Processingi

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi5 – 51N-linked (GlcNAc...)Imported
    Glycosylationi18 – 181N-linked (GlcNAc...)Imported
    Glycosylationi24 – 241N-linked (GlcNAc...)Imported
    Glycosylationi111 – 1111N-linked (GlcNAc...)Imported
    Glycosylationi117 – 1171N-linked (GlcNAc...)Imported
    Glycosylationi161 – 1611N-linked (GlcNAc...)Imported

    Keywords - PTMi

    Disulfide bondSAAS annotation

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    2NXYX-ray2.00A1-205[»]
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiQ49DS8.

    Family & Domainsi

    Family and domain databases

    Gene3Di2.170.40.20. 1 hit.
    InterProiIPR000777. HIV1_GP160.
    [Graphical view]
    PfamiPF00516. GP120. 1 hit.
    [Graphical view]
    SUPFAMiSSF56502. SSF56502. 1 hit.

    Sequencei

    Sequence statusi: Fragment.

    Q49DS8-1 [UniParc]FASTAAdd to Basket

    « Hide

    IRSENITNNA KIIIVQLNES VIINCTRPYN NTRRSTHVGP GQALFTTEII    50
    GDIRQAHCNI SGTSWNKTLQ QVTAKLKNLF NKTIVFKSPS GGDPEITTHS 100
    FNCGGEFFYC NTTNLFNNRE TVNNRTITLP CRIKQIINMW QGVGKAMYAP 150
    PIAGRINCSS NITGLLLTRD GGNGSQQNET FRPGGGDMRD NWRSELYKYK 200
    VVKIEPLG 208
    Length:208
    Mass (Da):23,212
    Last modified:September 13, 2005 - v1
    Checksum:iEEEDDE925D7E6C39
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported
    Non-terminal residuei208 – 2081Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY932129 Genomic DNA. Translation: AAY20506.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY932129 Genomic DNA. Translation: AAY20506.1 .

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    2NXY X-ray 2.00 A 1-205 [» ]
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Miscellaneous databases

    EvolutionaryTracei Q49DS8.

    Family and domain databases

    Gene3Di 2.170.40.20. 1 hit.
    InterProi IPR000777. HIV1_GP160.
    [Graphical view ]
    Pfami PF00516. GP120. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56502. SSF56502. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: TZMDE732-11-10Imported.
    2. "Risk of HIV-1 transmission by breastfeeding among mothers infected with recombinant and non-recombinant HIV-1 genotypes."
      Koulinska I.N., Villamor E., Msamanga G., Fawzi W., Blackard J., Renjifo B., Essex M.
      Virus Res. 120:191-198(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: TZMDE732-11-10Imported.
    3. Cited for: X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS) OF 1-205, GLYCOSYLATION AT ASN-5; ASN-18; ASN-24; ASN-111; ASN-117 AND ASN-161.

    Entry informationi

    Entry nameiQ49DS8_9HIV1
    AccessioniPrimary (citable) accession number: Q49DS8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 13, 2005
    Last sequence update: September 13, 2005
    Last modified: October 1, 2014
    This is version 48 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    3D-structureImported

    External Data

    Dasty 3