Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

DCC protein

Gene

DCC

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
DCC proteinImported
Gene namesi
Name:DCCImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA27170.

PTM / Processingi

Proteomic databases

PaxDbiQ49AK4.
PRIDEiQ49AK4.

Expressioni

Gene expression databases

GenevisibleiQ49AK4. HS.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000389140.

Structurei

3D structure databases

ProteinModelPortaliQ49AK4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1 – 6969Ig-like (immunoglobulin-like)InterPro annotationAdd
BLAST
Domaini73 – 16391Ig-like (immunoglobulin-like)InterPro annotationAdd
BLAST
Domaini168 – 26093Ig-like (immunoglobulin-like)InterPro annotationAdd
BLAST
Domaini265 – 35086Ig-like (immunoglobulin-like)InterPro annotationAdd
BLAST
Domaini365 – 45894Fibronectin type-IIIInterPro annotationAdd
BLAST
Domaini464 – 55491Fibronectin type-IIIInterPro annotationAdd
BLAST
Domaini559 – 65294Fibronectin type-IIIInterPro annotationAdd
BLAST
Domaini662 – 75594Fibronectin type-IIIInterPro annotationAdd
BLAST

Keywords - Domaini

RepeatSAAS annotation

Phylogenomic databases

eggNOGiKOG4221. Eukaryota.
ENOG410Z913. LUCA.
HOVERGENiHBG005455.
KOiK06765.

Family and domain databases

Gene3Di2.60.40.10. 8 hits.
InterProiIPR033012. DCC.
IPR003961. FN3_dom.
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR013098. Ig_I-set.
IPR003599. Ig_sub.
IPR003598. Ig_sub2.
[Graphical view]
PANTHERiPTHR10489:SF68. PTHR10489:SF68. 1 hit.
PfamiPF00041. fn3. 4 hits.
PF07679. I-set. 3 hits.
[Graphical view]
SMARTiSM00060. FN3. 4 hits.
SM00409. IG. 4 hits.
SM00408. IGc2. 4 hits.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 4 hits.
SSF49265. SSF49265. 3 hits.
PROSITEiPS50853. FN3. 4 hits.
PS50835. IG_LIKE. 4 hits.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q49AK4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
SGVPVIKWKK DGIHLALGMD ERKQQLSNGS LLIQNILHSR HHKPDEGLYQ
60 70 80 90 100
CEASLGDSGS IISRTAKVAV AGPLRFLSQT ESVTAFMGDT VLLKCEVIGE
110 120 130 140 150
PMPTIHWQKN QQDLTPIPGD SRVVVLPSGA LQISRLQPGD IGIYRCSARN
160 170 180 190 200
PASSRTGNEA EVRILSDPGL HRQLYFLQRP SNVVAIEGKD AVLEGCVSGY
210 220 230 240 250
PPPSFTWLRG EEVIQLRSKK YSLLGGSNLL ISNVTDDDSG MYTCVVTYKN
260 270 280 290 300
ENISASAELT VLVPPWFLNH PSNLYAYESM DIEFECTVSG KPVPTVNWMK
310 320 330 340 350
NGDVVIPSDY FQIVGGSNLR ILGVVKSDEG FYQCVAENEA GNAQTSAQLI
360 370 380 390 400
VPKPAIPSSS VLPSAPRDVV PVLVSSRFVR LSWRPPAEAK GNIQTFTVFF
410 420 430 440 450
SREGDNRERA LNTTQPGSLQ LTVGNLKPEA MYTFRVVAYN EWGPGESSQP
460 470 480 490 500
IKVATQPELQ VPGPVENLQA VSTSPTSILI TWEPPAYANG PVQGYRLFCT
510 520 530 540 550
EVSTGKEQNI EVDGLSYKLE GLKKFTEYSL RFLAYNRYGP GVSTDDITVV
560 570 580 590 600
TLSDVPSAPP QNVSLEVVNS RSIKVSWLPP PSGTQNGFIT GYKIRHRKTT
610 620 630 640 650
RRGEMETLEP NNLWYLFTGL EKGSQYSFQV SAMTVNGTGP PSNWYTAETP
660 670 680 690 700
ENDLDESQVP DQPSSLHVRP QTNCIIMSWT PPLNPNIVVR GYIIGYGVGS
710 720 730 740 750
PYAETVRVDS KQRYYSIERL ESSSHYVISL KAFNNAGEGV PLYESATTRS
760 770
ITVRRHNISK LHSNRPQTKH NV
Length:772
Mass (Da):84,992
Last modified:September 13, 2005 - v1
Checksum:iE444052269F016DC
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC036524 mRNA. Translation: AAH36524.1.
RefSeqiNP_005206.2. NM_005215.3.
UniGeneiHs.162025.

Genome annotation databases

GeneIDi1630.
KEGGihsa:1630.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC036524 mRNA. Translation: AAH36524.1.
RefSeqiNP_005206.2. NM_005215.3.
UniGeneiHs.162025.

3D structure databases

ProteinModelPortaliQ49AK4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000389140.

Proteomic databases

PaxDbiQ49AK4.
PRIDEiQ49AK4.

Protocols and materials databases

DNASUi1630.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi1630.
KEGGihsa:1630.

Organism-specific databases

CTDi1630.
PharmGKBiPA27170.

Phylogenomic databases

eggNOGiKOG4221. Eukaryota.
ENOG410Z913. LUCA.
HOVERGENiHBG005455.
KOiK06765.

Miscellaneous databases

ChiTaRSiDCC. human.
GenomeRNAii1630.

Gene expression databases

GenevisibleiQ49AK4. HS.

Family and domain databases

Gene3Di2.60.40.10. 8 hits.
InterProiIPR033012. DCC.
IPR003961. FN3_dom.
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR013098. Ig_I-set.
IPR003599. Ig_sub.
IPR003598. Ig_sub2.
[Graphical view]
PANTHERiPTHR10489:SF68. PTHR10489:SF68. 1 hit.
PfamiPF00041. fn3. 4 hits.
PF07679. I-set. 3 hits.
[Graphical view]
SMARTiSM00060. FN3. 4 hits.
SM00409. IG. 4 hits.
SM00408. IGc2. 4 hits.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 4 hits.
SSF49265. SSF49265. 3 hits.
PROSITEiPS50853. FN3. 4 hits.
PS50835. IG_LIKE. 4 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: TestisImported.

Entry informationi

Entry nameiQ49AK4_HUMAN
AccessioniPrimary (citable) accession number: Q49AK4
Entry historyi
Integrated into UniProtKB/TrEMBL: September 13, 2005
Last sequence update: September 13, 2005
Last modified: June 8, 2016
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.