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Protein
Submitted name:

UBR5 protein

Gene

UBR5

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei48Glycyl thioester intermediatePROSITE-ProRule annotation1

GO - Molecular functioni

Keywordsi

Biological processUbl conjugation pathwayPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
UBR5 proteinImported
Gene namesi
Name:UBR5Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Proteomic databases

PaxDbiQ49A65.
PeptideAtlasiQ49A65.

Expressioni

Gene expression databases

BgeeiENSG00000104517.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000429084.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 79HECT (E6AP-type E3 ubiquitin-protein ligase)InterPro annotationAdd BLAST79

Phylogenomic databases

eggNOGiKOG0943. Eukaryota.
COG5021. LUCA.
HOGENOMiHOG000046848.

Family and domain databases

InterProiView protein in InterPro
IPR000569. HECT_dom.
PfamiView protein in Pfam
PF00632. HECT. 1 hit.
SUPFAMiSSF56204. SSF56204. 1 hit.
PROSITEiView protein in PROSITE
PS50237. HECT. 1 hit.

Sequencei

Sequence statusi: Complete.

Q49A65-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSMTERQDLV YFWTSSPSLP ASEEGFQPMP SITIRPPDDQ HLPTANTCIS
60 70
RLYVPLYSSK QILKQKLLLA IKTKNFGFV
Length:79
Mass (Da):9,003
Last modified:September 13, 2005 - v1
Checksum:iE12B52482A48DDEE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC044598 mRNA. Translation: AAH44598.1.
UniGeneiHs.492445.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC044598 mRNA. Translation: AAH44598.1.
UniGeneiHs.492445.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000429084.

Proteomic databases

PaxDbiQ49A65.
PeptideAtlasiQ49A65.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiKOG0943. Eukaryota.
COG5021. LUCA.
HOGENOMiHOG000046848.

Miscellaneous databases

ChiTaRSiUBR5. human.

Gene expression databases

BgeeiENSG00000104517.

Family and domain databases

InterProiView protein in InterPro
IPR000569. HECT_dom.
PfamiView protein in Pfam
PF00632. HECT. 1 hit.
SUPFAMiSSF56204. SSF56204. 1 hit.
PROSITEiView protein in PROSITE
PS50237. HECT. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ49A65_HUMAN
AccessioniPrimary (citable) accession number: Q49A65
Entry historyiIntegrated into UniProtKB/TrEMBL: September 13, 2005
Last sequence update: September 13, 2005
Last modified: February 15, 2017
This is version 75 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.