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Protein
Submitted name:

Mucolipin 2

Gene

Mcoln2

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-RNO-3295583 TRP channels

Names & Taxonomyi

Protein namesi
Submitted name:
Mucolipin 2Imported
Gene namesi
Name:Mcoln2Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 2

Organism-specific databases

RGDi1308884 Mcoln2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei289 – 316HelicalSequence analysisAdd BLAST28
Transmembranei346 – 363HelicalSequence analysisAdd BLAST18
Transmembranei375 – 397HelicalSequence analysisAdd BLAST23
Transmembranei417 – 439HelicalSequence analysisAdd BLAST23
Transmembranei485 – 506HelicalSequence analysisAdd BLAST22

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSRNOG00000015089

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000020452

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini378 – 513PKD_channelInterPro annotationAdd BLAST136

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3733 Eukaryota
ENOG410Z1HH LUCA
GeneTreeiENSGT00390000017126
HOGENOMiHOG000232158
HOVERGENiHBG052430
KOiK04993
OMAiRRQIPWK
OrthoDBiEOG091G026A
TreeFamiTF317783

Family and domain databases

InterProiView protein in InterPro
IPR013122 PKD1_2_channel
PfamiView protein in Pfam
PF08016 PKD_channel, 1 hit

Sequencei

Sequence statusi: Complete.

Q499S1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPEGEETLDL PAWNRAPDPA WGPQHRAAVA SLDSEVKEEC LREDLKFYFM
60 70 80 90 100
SPCEKYRARR QIPWKLALQI LKIVMVTTQL VRFGLGNQLV VAFKEDNTVA
110 120 130 140 150
FKHLFLKGFS GVDEDDYSCS IYTQEDAYES IFFAIKQYRH LKNISLATLG
160 170 180 190 200
YGKSEDNRTG LRFCKQHYKS GAMFSSNETL NIDSDIETDC THLDLQVLTK
210 220 230 240 250
DPEDWAQASF FRLDFHRLVQ VDISFALKGI DLQAVHSREV PDCYLFQNTI
260 270 280 290 300
TFDNTAHSGK IKIYFNSEAN IEECKHMNLS GSLQRSTRYV LVFDVFVIAI
310 320 330 340 350
CLASLILCTR SIVLALRLRK RFLNFFLEKY KQHVCDADRW EFINGWYVLV
360 370 380 390 400
TISDLMTIIG SILKMEIKAK NLTNYDLCSI LLGTSTLLVW VGVIRYLGYF
410 420 430 440 450
QTYNALILTM QASLPKVLRF SACAGLIYLG YTFCGWIVLG PYHEKFENLN
460 470 480 490 500
IVAECLFSLV NGDDMFATFA QIQQKSLLVW LFSRLYLYSF ISLFIYMVLS
510 520 530 540 550
LFIALITDSY HTIKKYQQNG FPETDLQKFL KESGSKEGYQ KEPSALLPCF
560
CCLRRRGSDD HLVLVD
Length:566
Mass (Da):65,160
Last modified:September 13, 2005 - v1
Checksum:iAD597A6E38958A0D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07013714 Genomic DNA No translation available.
AABR07013715 Genomic DNA No translation available.
BC099787 mRNA Translation: AAH99787.1
RefSeqiNP_001034094.1, NM_001039005.1
UniGeneiRn.35113

Genome annotation databases

EnsembliENSRNOT00000020452; ENSRNOP00000020452; ENSRNOG00000015089
GeneIDi292168
KEGGirno:292168

Similar proteinsi

Entry informationi

Entry nameiQ499S1_RAT
AccessioniPrimary (citable) accession number: Q499S1
Entry historyiIntegrated into UniProtKB/TrEMBL: September 13, 2005
Last sequence update: September 13, 2005
Last modified: May 23, 2018
This is version 84 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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