Q499G5 (Q499G5_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
E2F3 protein EMBL AAH99908.1

Gene names

Name:

E2F3 EMBL AAH99908.1

Organism

Homo sapiens (Human) EMBL AAH99908.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	126 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Subcellular location	Nucleus By similarity RuleBase RU003796.
Sequence similarities	Belongs to the E2F/DP family. RuleBase RU003796

Ontologies

Keywords
Biological process	Transcription Transcription regulation RuleBase RU003796
Cellular component	Nucleus RuleBase RU003796
Ligand	DNA-binding RuleBase RU003796
Gene Ontology (GO)
Biological_process	transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	transcription factor complex Inferred from electronic annotation. Source: InterPro
Molecular_function	DNA binding Inferred from electronic annotation. Source: UniProtKB-KW sequence-specific DNA binding transcription factor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q499G5 [UniParc]. Last modified September 13, 2005. Version 1. Checksum: 20EC8CA67D75D010	FASTA	126	13,874
	10 20 30 40 50 60 MDKRALLAGG GGPPAKRRLE LGESGHQYLS DGLKTPKGKG RAALRSPDSP KKKTRYDTSL 70 80 90 100 110 120 GLLTKKFIQL LSQSPDGVLD LNKAAEVLKV QKRRIYDITN VLEGISDLFD AYDLEKLPLV EDFMCS

References

[1]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M. , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J. Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Placenta EMBL AAH99908.1.

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Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BC099908 mRNA. Translation: AAH99908.1.
IPI	IPI00647428.
UniGene	Hs.269408. Hs.703174.
3D structure databases
ProteinModelPortal	Q499G5.
SMR	Q499G5. Positions 54-105.
ModBase	Search...
Protein-protein interaction databases
STRING	Q499G5.
Proteomic databases
PRIDE	Q499G5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Organism-specific databases
PharmGKB	PA27573.
Phylogenomic databases
HOGENOM	HOG000207031.
Gene expression databases
ArrayExpress	Q499G5.
Bgee	Q499G5.
Family and domain databases
Gene3D	1.10.10.10. 1 hit.
InterPro	IPR015633. E2F. IPR003316. E2F_TDP. IPR011991. WHTH_DNA-bd_dom. [Graphical view]
PANTHER	PTHR12081. PTHR12081. 1 hit.
Pfam	PF02319. E2F_TDP. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	13615291.

Entry information

Entry name

Q499G5_HUMAN

Accession

Primary (citable) accession number: Q499G5

Entry history

Integrated into UniProtKB/TrEMBL:	September 13, 2005
Last sequence update:	September 13, 2005
Last modified:	May 1, 2013
This is version 69 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.