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Q49988

- PPGK_MYCLE

UniProt

Q49988 - PPGK_MYCLE

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Protein

Polyphosphate glucokinase

Gene

ppgK

Organism
Mycobacterium leprae (strain TN)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the phosphorylation of glucose using polyphosphate or ATP as the phosphoryl donor.

Catalytic activityi

(Phosphate)(n) + D-glucose = (phosphate)(n-1) + D-glucose 6-phosphate.

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi83 – 886ATPSequence Analysis

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. polyphosphate-glucose phosphotransferase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Polyphosphate glucokinase (EC:2.7.1.63)
Alternative name(s):
Polyphosphate--glucose phosphotransferase
Gene namesi
Name:ppgK
Ordered Locus Names:ML1023
ORF Names:u1764fg
OrganismiMycobacterium leprae (strain TN)
Taxonomic identifieri272631 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacterium
ProteomesiUP000000806: Chromosome

Organism-specific databases

LepromaiML1023.

Subcellular locationi

Cytoplasm By similarity

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 324324Polyphosphate glucokinasePRO_0000058535Add
BLAST

Interactioni

Subunit structurei

Monomer.By similarity

Protein-protein interaction databases

STRINGi272631.ML1023.

Structurei

3D structure databases

ProteinModelPortaliQ49988.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiCOG1940.
HOGENOMiHOG000150086.
KOiK00886.
OMAiWDGPVGI.
OrthoDBiEOG6VTK5N.

Family and domain databases

InterProiIPR000600. ROK.
[Graphical view]
PfamiPF00480. ROK. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q49988-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MIRLRSAAAR DRCQVLSLAY RITVAGRCQT VSPHHRQAKV SEQPSLAKEI
60 70 80 90 100
AITSTDATAD TPRTSPPSDT AGTTSRHRGF GIDIGGSSIK GGIVDLDIGQ
110 120 130 140 150
LIGDRIKLLT PQPATPLAVA KTIAEVVNAF GWTAPLGVTY PGVVTQGVVR
160 170 180 190 200
TAANVDDSWI GTNARDIISA ELNSQEVTIL NDADAAGLAE GRYGAGKNNS
210 220 230 240 250
GLIVLLTFGT GIGSAVIHNG KLIPNTEFGH LEVDGKEAEQ RAASSVKDKY
260 270 280 290 300
KWSYRTWAKQ VTRVLVAIEN AMCPDLFIAG GGISRKADRW IPLLENRTPM
310 320
VAAALQNTAG IVGAAMASTA DVTH
Length:324
Mass (Da):34,102
Last modified:November 1, 1996 - v1
Checksum:i563A5C63CC9EF6EA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U15181 Genomic DNA. Translation: AAA62940.1.
AL583920 Genomic DNA. Translation: CAC31404.1.
PIRiA87037.
RefSeqiNP_301756.1. NC_002677.1.
WP_010908080.1. NC_002677.1.

Genome annotation databases

EnsemblBacteriaiCAC31404; CAC31404; CAC31404.
GeneIDi910085.
KEGGimle:ML1023.
PATRICi18053814. VBIMycLep78757_1852.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U15181 Genomic DNA. Translation: AAA62940.1 .
AL583920 Genomic DNA. Translation: CAC31404.1 .
PIRi A87037.
RefSeqi NP_301756.1. NC_002677.1.
WP_010908080.1. NC_002677.1.

3D structure databases

ProteinModelPortali Q49988.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 272631.ML1023.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAC31404 ; CAC31404 ; CAC31404 .
GeneIDi 910085.
KEGGi mle:ML1023.
PATRICi 18053814. VBIMycLep78757_1852.

Organism-specific databases

Lepromai ML1023.

Phylogenomic databases

eggNOGi COG1940.
HOGENOMi HOG000150086.
KOi K00886.
OMAi WDGPVGI.
OrthoDBi EOG6VTK5N.

Family and domain databases

InterProi IPR000600. ROK.
[Graphical view ]
Pfami PF00480. ROK. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Smith D.R., Robison K.
    Submitted (SEP-1994) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: TN.

Entry informationi

Entry nameiPPGK_MYCLE
AccessioniPrimary (citable) accession number: Q49988
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1999
Last sequence update: November 1, 1996
Last modified: October 29, 2014
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3