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Q49988

- PPGK_MYCLE

UniProt

Q49988 - PPGK_MYCLE

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Protein

Polyphosphate glucokinase

Gene
ppgK, ML1023, u1764fg
Organism
Mycobacterium leprae (strain TN)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the phosphorylation of glucose using polyphosphate or ATP as the phosphoryl donor.

Catalytic activityi

(Phosphate)(n) + D-glucose = (phosphate)(n-1) + D-glucose 6-phosphate.

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi83 – 886ATP Reviewed prediction

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. polyphosphate-glucose phosphotransferase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Polyphosphate glucokinase (EC:2.7.1.63)
Alternative name(s):
Polyphosphate--glucose phosphotransferase
Gene namesi
Name:ppgK
Ordered Locus Names:ML1023
ORF Names:u1764fg
OrganismiMycobacterium leprae (strain TN)
Taxonomic identifieri272631 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacterium
ProteomesiUP000000806: Chromosome

Organism-specific databases

LepromaiML1023.

Subcellular locationi

Cytoplasm By similarity

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 324324Polyphosphate glucokinasePRO_0000058535Add
BLAST

Interactioni

Subunit structurei

Monomer By similarity.

Protein-protein interaction databases

STRINGi272631.ML1023.

Structurei

3D structure databases

ProteinModelPortaliQ49988.

Family & Domainsi

Phylogenomic databases

eggNOGiCOG1940.
HOGENOMiHOG000150086.
KOiK00886.
OMAiWDGPVGI.
OrthoDBiEOG6VTK5N.

Family and domain databases

InterProiIPR000600. ROK.
[Graphical view]
PfamiPF00480. ROK. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q49988-1 [UniParc]FASTAAdd to Basket

« Hide

MIRLRSAAAR DRCQVLSLAY RITVAGRCQT VSPHHRQAKV SEQPSLAKEI    50
AITSTDATAD TPRTSPPSDT AGTTSRHRGF GIDIGGSSIK GGIVDLDIGQ 100
LIGDRIKLLT PQPATPLAVA KTIAEVVNAF GWTAPLGVTY PGVVTQGVVR 150
TAANVDDSWI GTNARDIISA ELNSQEVTIL NDADAAGLAE GRYGAGKNNS 200
GLIVLLTFGT GIGSAVIHNG KLIPNTEFGH LEVDGKEAEQ RAASSVKDKY 250
KWSYRTWAKQ VTRVLVAIEN AMCPDLFIAG GGISRKADRW IPLLENRTPM 300
VAAALQNTAG IVGAAMASTA DVTH 324
Length:324
Mass (Da):34,102
Last modified:November 1, 1996 - v1
Checksum:i563A5C63CC9EF6EA
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U15181 Genomic DNA. Translation: AAA62940.1.
AL583920 Genomic DNA. Translation: CAC31404.1.
PIRiA87037.
RefSeqiNP_301756.1. NC_002677.1.
WP_010908080.1. NC_002677.1.

Genome annotation databases

EnsemblBacteriaiCAC31404; CAC31404; CAC31404.
GeneIDi910085.
KEGGimle:ML1023.
PATRICi18053814. VBIMycLep78757_1852.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U15181 Genomic DNA. Translation: AAA62940.1 .
AL583920 Genomic DNA. Translation: CAC31404.1 .
PIRi A87037.
RefSeqi NP_301756.1. NC_002677.1.
WP_010908080.1. NC_002677.1.

3D structure databases

ProteinModelPortali Q49988.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 272631.ML1023.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAC31404 ; CAC31404 ; CAC31404 .
GeneIDi 910085.
KEGGi mle:ML1023.
PATRICi 18053814. VBIMycLep78757_1852.

Organism-specific databases

Lepromai ML1023.

Phylogenomic databases

eggNOGi COG1940.
HOGENOMi HOG000150086.
KOi K00886.
OMAi WDGPVGI.
OrthoDBi EOG6VTK5N.

Family and domain databases

InterProi IPR000600. ROK.
[Graphical view ]
Pfami PF00480. ROK. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Smith D.R., Robison K.
    Submitted (SEP-1994) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: TN.

Entry informationi

Entry nameiPPGK_MYCLE
AccessioniPrimary (citable) accession number: Q49988
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1999
Last sequence update: November 1, 1996
Last modified: September 3, 2014
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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