Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q49988

- PPGK_MYCLE

UniProt

Q49988 - PPGK_MYCLE

Protein

Polyphosphate glucokinase

Gene

ppgK

Organism
Mycobacterium leprae (strain TN)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 79 (01 Oct 2014)
      Sequence version 1 (01 Nov 1996)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalyzes the phosphorylation of glucose using polyphosphate or ATP as the phosphoryl donor.

    Catalytic activityi

    (Phosphate)(n) + D-glucose = (phosphate)(n-1) + D-glucose 6-phosphate.

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi83 – 886ATPSequence Analysis

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. polyphosphate-glucose phosphotransferase activity Source: UniProtKB-EC

    Keywords - Molecular functioni

    Kinase, Transferase

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Polyphosphate glucokinase (EC:2.7.1.63)
    Alternative name(s):
    Polyphosphate--glucose phosphotransferase
    Gene namesi
    Name:ppgK
    Ordered Locus Names:ML1023
    ORF Names:u1764fg
    OrganismiMycobacterium leprae (strain TN)
    Taxonomic identifieri272631 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacterium
    ProteomesiUP000000806: Chromosome

    Organism-specific databases

    LepromaiML1023.

    Subcellular locationi

    Cytoplasm By similarity

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 324324Polyphosphate glucokinasePRO_0000058535Add
    BLAST

    Interactioni

    Subunit structurei

    Monomer.By similarity

    Protein-protein interaction databases

    STRINGi272631.ML1023.

    Structurei

    3D structure databases

    ProteinModelPortaliQ49988.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    eggNOGiCOG1940.
    HOGENOMiHOG000150086.
    KOiK00886.
    OMAiWDGPVGI.
    OrthoDBiEOG6VTK5N.

    Family and domain databases

    InterProiIPR000600. ROK.
    [Graphical view]
    PfamiPF00480. ROK. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q49988-1 [UniParc]FASTAAdd to Basket

    « Hide

    MIRLRSAAAR DRCQVLSLAY RITVAGRCQT VSPHHRQAKV SEQPSLAKEI    50
    AITSTDATAD TPRTSPPSDT AGTTSRHRGF GIDIGGSSIK GGIVDLDIGQ 100
    LIGDRIKLLT PQPATPLAVA KTIAEVVNAF GWTAPLGVTY PGVVTQGVVR 150
    TAANVDDSWI GTNARDIISA ELNSQEVTIL NDADAAGLAE GRYGAGKNNS 200
    GLIVLLTFGT GIGSAVIHNG KLIPNTEFGH LEVDGKEAEQ RAASSVKDKY 250
    KWSYRTWAKQ VTRVLVAIEN AMCPDLFIAG GGISRKADRW IPLLENRTPM 300
    VAAALQNTAG IVGAAMASTA DVTH 324
    Length:324
    Mass (Da):34,102
    Last modified:November 1, 1996 - v1
    Checksum:i563A5C63CC9EF6EA
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U15181 Genomic DNA. Translation: AAA62940.1.
    AL583920 Genomic DNA. Translation: CAC31404.1.
    PIRiA87037.
    RefSeqiNP_301756.1. NC_002677.1.
    WP_010908080.1. NC_002677.1.

    Genome annotation databases

    EnsemblBacteriaiCAC31404; CAC31404; CAC31404.
    GeneIDi910085.
    KEGGimle:ML1023.
    PATRICi18053814. VBIMycLep78757_1852.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U15181 Genomic DNA. Translation: AAA62940.1 .
    AL583920 Genomic DNA. Translation: CAC31404.1 .
    PIRi A87037.
    RefSeqi NP_301756.1. NC_002677.1.
    WP_010908080.1. NC_002677.1.

    3D structure databases

    ProteinModelPortali Q49988.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 272631.ML1023.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAC31404 ; CAC31404 ; CAC31404 .
    GeneIDi 910085.
    KEGGi mle:ML1023.
    PATRICi 18053814. VBIMycLep78757_1852.

    Organism-specific databases

    Lepromai ML1023.

    Phylogenomic databases

    eggNOGi COG1940.
    HOGENOMi HOG000150086.
    KOi K00886.
    OMAi WDGPVGI.
    OrthoDBi EOG6VTK5N.

    Family and domain databases

    InterProi IPR000600. ROK.
    [Graphical view ]
    Pfami PF00480. ROK. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Smith D.R., Robison K.
      Submitted (SEP-1994) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: TN.

    Entry informationi

    Entry nameiPPGK_MYCLE
    AccessioniPrimary (citable) accession number: Q49988
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 15, 1999
    Last sequence update: November 1, 1996
    Last modified: October 1, 2014
    This is version 79 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    External Data

    Dasty 3