Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q49988 (PPGK_MYCLE) Reviewed, UniProtKB/Swiss-Prot

Last modified November 13, 2013. Version 76. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Polyphosphate glucokinase

EC=2.7.1.63
Alternative name(s):
Polyphosphate--glucose phosphotransferase
Gene names
Name:ppgK
Ordered Locus Names:ML1023
ORF Names:u1764fg
OrganismMycobacterium leprae (strain TN) [Complete proteome] [HAMAP]
Taxonomic identifier272631 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacterium

Protein attributes

Sequence length324 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the phosphorylation of glucose using polyphosphate or ATP as the phosphoryl donor.

Catalytic activity

(Phosphate)(n) + D-glucose = (phosphate)(n-1) + D-glucose 6-phosphate.

Subunit structure

Monomer By similarity.

Subcellular location

Cytoplasm By similarity.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

polyphosphate-glucose phosphotransferase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 324324Polyphosphate glucokinase
PRO_0000058535

Regions

Nucleotide binding83 – 886ATP Potential

Sequences

Sequence LengthMass (Da)Tools
Q49988 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: 563A5C63CC9EF6EA

FASTA32434,102
        10         20         30         40         50         60 
MIRLRSAAAR DRCQVLSLAY RITVAGRCQT VSPHHRQAKV SEQPSLAKEI AITSTDATAD 

        70         80         90        100        110        120 
TPRTSPPSDT AGTTSRHRGF GIDIGGSSIK GGIVDLDIGQ LIGDRIKLLT PQPATPLAVA 

       130        140        150        160        170        180 
KTIAEVVNAF GWTAPLGVTY PGVVTQGVVR TAANVDDSWI GTNARDIISA ELNSQEVTIL 

       190        200        210        220        230        240 
NDADAAGLAE GRYGAGKNNS GLIVLLTFGT GIGSAVIHNG KLIPNTEFGH LEVDGKEAEQ 

       250        260        270        280        290        300 
RAASSVKDKY KWSYRTWAKQ VTRVLVAIEN AMCPDLFIAG GGISRKADRW IPLLENRTPM 

       310        320 
VAAALQNTAG IVGAAMASTA DVTH 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U15181 Genomic DNA. Translation: AAA62940.1.
AL583920 Genomic DNA. Translation: CAC31404.1.
PIRA87037.
RefSeqNP_301756.1. NC_002677.1.

3D structure databases

ProteinModelPortalQ49988.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING272631.ML1023.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAC31404; CAC31404; CAC31404.
GeneID910085.
KEGGmle:ML1023.
PATRIC18053814. VBIMycLep78757_1852.

Organism-specific databases

LepromaML1023.
CMRSearch...

Phylogenomic databases

eggNOGCOG1940.
HOGENOMHOG000150086.
KOK00886.
OMASWIGTDA.
OrthoDBEOG6VTK5N.
ProtClustDBCLSK2460514.

Family and domain databases

InterProIPR000600. ROK.
[Graphical view]
PfamPF00480. ROK. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePPGK_MYCLE
AccessionPrimary (citable) accession number: Q49988
Entry history
Integrated into UniProtKB/Swiss-Prot: July 15, 1999
Last sequence update: November 1, 1996
Last modified: November 13, 2013
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program