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Protein

Centrosomal protein of 170 kDa protein B

Gene

cep170b

Organism
Xenopus laevis (African clawed frog)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Plays a role in microtubule organization.By similarity

Names & Taxonomyi

Protein namesi
Recommended name:
Centrosomal protein of 170 kDa protein B
Alternative name(s):
Centrosomal protein 170B
Short name:
Cep170B
Gene namesi
Name:cep170b
OrganismiXenopus laevis (African clawed frog)
Taxonomic identifieri8355 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusXenopus

Organism-specific databases

XenbaseiXB-GENE-5943463. cep170b.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton, Microtubule

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 16101610Centrosomal protein of 170 kDa protein BPRO_0000282891Add
BLAST

Interactioni

Protein-protein interaction databases

BioGridi592489. 1 interaction.
IntActiQ498L0. 1 interaction.

Structurei

3D structure databases

ProteinModelPortaliQ498L0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini23 – 7351FHAPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the CEP170 family.Curated
Contains 1 FHA domain.PROSITE-ProRule annotation

Phylogenomic databases

HOVERGENiHBG108016.
KOiK16463.

Family and domain databases

Gene3Di2.60.200.20. 1 hit.
InterProiIPR029300. CEP170_C.
IPR000253. FHA_dom.
IPR008984. SMAD_FHA_domain.
[Graphical view]
PfamiPF15308. CEP170_C. 2 hits.
PF00498. FHA. 1 hit.
[Graphical view]
SMARTiSM00240. FHA. 1 hit.
[Graphical view]
SUPFAMiSSF49879. SSF49879. 1 hit.
PROSITEiPS50006. FHA_DOMAIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q498L0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSVTSWFLVS SSGTRHRLPR EMIFVGREDC ELMLRSRSVD KQHAVINYDS
60 70 80 90 100
DKDEHRVKDL GSLNGTFIND VRIPDQKYIT LKLNDNIRFG YDINTYVLEQ
110 120 130 140 150
IQHQVPEEAL KYCDPPVIAF EQIPASSDKH EKYTSHLQMC SKTSAVREDQ
160 170 180 190 200
FKEQGAHMDS SQAKQEKVDK KSATDVPAYR TPLYGQPSWW GEDDDNKLGK
210 220 230 240 250
EGRSQDEHYS ERPKDMTQHE EEVSDNMGYR DSPDQCMYPF RREPSYFEIP
260 270 280 290 300
TKDFQQPVKP PETQVYEIPT KDTDTVPPVT PPVMQSHASF TIEFDDCKPG
310 320 330 340 350
KIKIKDHVTK PSMRQRKTAG KEPGPTEMVS AESKVADWLV HNDPSLIRRP
360 370 380 390 400
SPGEDVYSTK SDLPIHNRTL KGNKHEDGTQ SDSEDPLVTK PEQETGTADH
410 420 430 440 450
PQHQRQFNRE PEELLHSQQA FVIEFFDDDA PRKKRSQSFT HNSNSPPNDT
460 470 480 490 500
DPILKAKVDK RKGTVHVEKV STNGTGSTAP ASKSLSSPSF PQRSNSFRRE
510 520 530 540 550
KTEDRIASTP ITARLPGKNY GSVGKKSKLA QEFAAEYMHE QAEVVKQAAE
560 570 580 590 600
KPMTLPLSAS ILQQPASQVQ ISSQVQAMPV TSDVRSETIK NEEEDNLSDA
610 620 630 640 650
GTYTIETETQ DREVEQARKM IDQVFGVFEP DEYSKISSTV YRPVINKGKE
660 670 680 690 700
EHLGSEPSMT HKPIMSLSTP PIKLSNGLQA EPLIERPGSS SKSGQKWVSR
710 720 730 740 750
WASLADSYPD ASPTSPSDSQ KQGFIADDED VIERIEVQGE ADPTVPSRTR
760 770 780 790 800
RLLPQLPPEN VMPTIFVCQE SFSAESQRKH VEEPEKGISA ENSSLLLVQE
810 820 830 840 850
ELDPDSLSDT SRSDDGVLSV RKSAKASKIY RNGWKGEEPH SRESSVQRTL
860 870 880 890 900
VSSSEKKSTC FYVGNDDMGS LKQTTSGLSS KDVVKNHESH INLKANVHSN
910 920 930 940 950
VETPSAERLV NQFHKKENGS AKDPLSFVRQ ESFTKEKSSS NVSPNKLPHI
960 970 980 990 1000
STHPLLKDLS VTKSSHDYSQ ETRLILKETE TALAALEAKL FTQSHLDELE
1010 1020 1030 1040 1050
NTPSLRDDSL SGESDVDTAS TVSLVSDKNA PIHSQQNRIV NLQKEKSSST
1060 1070 1080 1090 1100
SSIQEQYCQS SARERLSEKR RTVPADAGTR SITKRVGMTR STGARGSLDF
1110 1120 1130 1140 1150
TDEERSSSLP YMPVSETVSS DYENSSSRHI SRRKPIGQTC KEDSSRSSNA
1160 1170 1180 1190 1200
QKVQQALTRS NSLSTPRPTR ASKLRRARLG ESSDNECADG ERSNISPGTS
1210 1220 1230 1240 1250
SANSSSAKSS TEPKKPSRLD ILAMPRKRAG SFNVPSDSET YSSVKAMFSG
1260 1270 1280 1290 1300
RSVDQTYTSR KPAVAESKQP PKKPVAPTQK QTPSKARSSS VKYSSSSTTQ
1310 1320 1330 1340 1350
TSRSSSVSRH HKSSRQDEDE VEQEVYNNFM AQSVEIAEIA RLSQTLVKDV
1360 1370 1380 1390 1400
ASLAREIHDV AGDGDSQSSS GTGQSTSISS VPNTPASTIS AREETIKRPL
1410 1420 1430 1440 1450
QRTRPLQLVH HIPEASLNYQ KIPPGSTGLE DFDQNMNDSR EDPSKRRARN
1460 1470 1480 1490 1500
IEEVIFDNLM LNPVSQLSHT ICSDTEVLTE KMKVLFQNTE KNWEEIEAKI
1510 1520 1530 1540 1550
NSENEVPILK TSNKEISSIL KELRRVQKQL EVINAIIDRS GNPEDTASNK
1560 1570 1580 1590 1600
KTSSTLLTSN ALPRTTNNSA ARTQSQTPGH LRNYIHKSSS SSSRSPGSSF
1610
SRDDEETYIV
Length:1,610
Mass (Da):179,342
Last modified:September 13, 2005 - v1
Checksum:i38F454C97D092DE0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC100173 mRNA. Translation: AAI00174.1.
RefSeqiNP_001089648.1. NM_001096179.1.
UniGeneiXl.13597.

Genome annotation databases

GeneIDi734708.
KEGGixla:734708.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC100173 mRNA. Translation: AAI00174.1.
RefSeqiNP_001089648.1. NM_001096179.1.
UniGeneiXl.13597.

3D structure databases

ProteinModelPortaliQ498L0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi592489. 1 interaction.
IntActiQ498L0. 1 interaction.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi734708.
KEGGixla:734708.

Organism-specific databases

CTDi283638.
XenbaseiXB-GENE-5943463. cep170b.

Phylogenomic databases

HOVERGENiHBG108016.
KOiK16463.

Family and domain databases

Gene3Di2.60.200.20. 1 hit.
InterProiIPR029300. CEP170_C.
IPR000253. FHA_dom.
IPR008984. SMAD_FHA_domain.
[Graphical view]
PfamiPF15308. CEP170_C. 2 hits.
PF00498. FHA. 1 hit.
[Graphical view]
SMARTiSM00240. FHA. 1 hit.
[Graphical view]
SUPFAMiSSF49879. SSF49879. 1 hit.
PROSITEiPS50006. FHA_DOMAIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. NIH - Xenopus Gene Collection (XGC) project
    Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Ovary.

Entry informationi

Entry nameiC170B_XENLA
AccessioniPrimary (citable) accession number: Q498L0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 3, 2007
Last sequence update: September 13, 2005
Last modified: May 11, 2016
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.