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Protein
Submitted name:

Protein Rbx1

Gene

Rbx1

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

ReactomeiR-RNO-110314. Recognition of DNA damage by PCNA-containing replication complex.
R-RNO-1170546. Prolactin receptor signaling.
R-RNO-1234176. Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha.
R-RNO-195253. Degradation of beta-catenin by the destruction complex.
R-RNO-4641258. Degradation of DVL.
R-RNO-5610780. Degradation of GLI1 by the proteasome.
R-RNO-5610785. GLI3 is processed to GLI3R by the proteasome.
R-RNO-5632684. Hedgehog 'on' state.
R-RNO-5696394. DNA Damage Recognition in GG-NER.
R-RNO-5696395. Formation of Incision Complex in GG-NER.
R-RNO-5696400. Dual Incision in GG-NER.
R-RNO-6781823. Formation of TC-NER Pre-Incision Complex.
R-RNO-6782135. Dual incision in TC-NER.
R-RNO-6782210. Gap-filling DNA repair synthesis and ligation in TC-NER.
R-RNO-983168. Antigen processing: Ubiquitination & Proteasome degradation.

Names & Taxonomyi

Protein namesi
Submitted name:
Protein Rbx1Imported
Submitted name:
Ring-box 1Imported
Gene namesi
Name:Rbx1Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 7

Organism-specific databases

RGDi1308453. Rbx1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

PTM databases

PhosphoSiteiQ498D8.

Expressioni

Gene expression databases

BgeeiENSRNOG00000019214.

Interactioni

GO - Molecular functioni

  • cullin family protein binding Source: GO_Central
  • protein complex binding Source: RGD

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000025979.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini53 – 9846RING-typeInterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiKOG2930. Eukaryota.
COG5194. LUCA.
GeneTreeiENSGT00390000017058.
HOGENOMiHOG000171951.
HOVERGENiHBG001507.
KOiK03868.
OMAiARSVCPL.
OrthoDBiEOG091G0TA5.
TreeFamiTF105503.

Family and domain databases

Gene3Di3.30.40.10. 1 hit.
InterProiIPR001841. Znf_RING.
IPR013083. Znf_RING/FYVE/PHD.
IPR024766. Znf_RING_H2.
[Graphical view]
PfamiPF12678. zf-rbx1. 1 hit.
[Graphical view]
PROSITEiPS50089. ZF_RING_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q498D8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAAMDVDTP SGTNSGAGKK RFEVKKWNAV ALWAWDIVVD NCAICRNHIM
60 70 80 90 100
DLCIECQANQ ASATSEECTV AWGVCNHAFH FHCISRWLKT RQVCPLDNRE

WEFQKYGH
Length:108
Mass (Da):12,274
Last modified:September 13, 2005 - v1
Checksum:i30FC5ADF66096C0E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07058535 Genomic DNA. No translation available.
AABR07058536 Genomic DNA. No translation available.
BC100258 mRNA. Translation: AAI00259.1.
RefSeqiNP_001029307.1. NM_001034135.1.
UniGeneiRn.8068.

Genome annotation databases

EnsembliENSRNOT00000086603; ENSRNOP00000069049; ENSRNOG00000058914.
GeneIDi300084.
KEGGirno:300084.
UCSCiRGD:1308453. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07058535 Genomic DNA. No translation available.
AABR07058536 Genomic DNA. No translation available.
BC100258 mRNA. Translation: AAI00259.1.
RefSeqiNP_001029307.1. NM_001034135.1.
UniGeneiRn.8068.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000025979.

PTM databases

PhosphoSiteiQ498D8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000086603; ENSRNOP00000069049; ENSRNOG00000058914.
GeneIDi300084.
KEGGirno:300084.
UCSCiRGD:1308453. rat.

Organism-specific databases

CTDi9978.
RGDi1308453. Rbx1.

Phylogenomic databases

eggNOGiKOG2930. Eukaryota.
COG5194. LUCA.
GeneTreeiENSGT00390000017058.
HOGENOMiHOG000171951.
HOVERGENiHBG001507.
KOiK03868.
OMAiARSVCPL.
OrthoDBiEOG091G0TA5.
TreeFamiTF105503.

Enzyme and pathway databases

ReactomeiR-RNO-110314. Recognition of DNA damage by PCNA-containing replication complex.
R-RNO-1170546. Prolactin receptor signaling.
R-RNO-1234176. Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha.
R-RNO-195253. Degradation of beta-catenin by the destruction complex.
R-RNO-4641258. Degradation of DVL.
R-RNO-5610780. Degradation of GLI1 by the proteasome.
R-RNO-5610785. GLI3 is processed to GLI3R by the proteasome.
R-RNO-5632684. Hedgehog 'on' state.
R-RNO-5696394. DNA Damage Recognition in GG-NER.
R-RNO-5696395. Formation of Incision Complex in GG-NER.
R-RNO-5696400. Dual Incision in GG-NER.
R-RNO-6781823. Formation of TC-NER Pre-Incision Complex.
R-RNO-6782135. Dual incision in TC-NER.
R-RNO-6782210. Gap-filling DNA repair synthesis and ligation in TC-NER.
R-RNO-983168. Antigen processing: Ubiquitination & Proteasome degradation.

Gene expression databases

BgeeiENSRNOG00000019214.

Family and domain databases

Gene3Di3.30.40.10. 1 hit.
InterProiIPR001841. Znf_RING.
IPR013083. Znf_RING/FYVE/PHD.
IPR024766. Znf_RING_H2.
[Graphical view]
PfamiPF12678. zf-rbx1. 1 hit.
[Graphical view]
PROSITEiPS50089. ZF_RING_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ498D8_RAT
AccessioniPrimary (citable) accession number: Q498D8
Entry historyi
Integrated into UniProtKB/TrEMBL: September 13, 2005
Last sequence update: September 13, 2005
Last modified: September 7, 2016
This is version 105 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.