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Protein

Alpha-1,3-glucosyltransferase

Gene

Alg8

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Pathwayi: protein glycosylation

This protein is involved in the pathway protein glycosylation, which is part of Protein modification.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway protein glycosylation and in Protein modification.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferaseUniRule annotation, Transferase

Enzyme and pathway databases

UniPathwayiUPA00378

Protein family/group databases

CAZyiGT57 Glycosyltransferase Family 57

Names & Taxonomyi

Protein namesi
Recommended name:
Alpha-1,3-glucosyltransferaseUniRule annotation (EC:2.4.1.-UniRule annotation)
Gene namesi
Name:Alg8Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi1305468 Alg8

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei104 – 122HelicalUniRule annotationAdd BLAST19
Transmembranei143 – 158HelicalUniRule annotationAdd BLAST16
Transmembranei188 – 214HelicalUniRule annotationAdd BLAST27
Transmembranei234 – 259HelicalUniRule annotationAdd BLAST26
Transmembranei336 – 355HelicalUniRule annotationAdd BLAST20
Transmembranei361 – 378HelicalUniRule annotationAdd BLAST18
Transmembranei429 – 449HelicalUniRule annotationAdd BLAST21
Transmembranei489 – 508HelicalUniRule annotationAdd BLAST20

Keywords - Cellular componenti

Endoplasmic reticulumUniRule annotation, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 18Sequence analysisAdd BLAST18
ChainiPRO_500423503219 – 526Alpha-1,3-glucosyltransferaseSequence analysisAdd BLAST508

PTM databases

iPTMnetiQ497D1
PhosphoSitePlusiQ497D1

Expressioni

Gene expression databases

GenevisibleiQ497D1 RN

Family & Domainsi

Sequence similaritiesi

Belongs to the ALG6/ALG8 glucosyltransferase family.UniRule annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGiKOG2576 Eukaryota
ENOG410XPPM LUCA
HOGENOMiHOG000168174
HOVERGENiHBG024332
KOiK03849
PhylomeDBiQ497D1

Family and domain databases

InterProiView protein in InterPro
IPR004856 Glyco_trans_ALG6/ALG8
PANTHERiPTHR12413 PTHR12413, 1 hit
PfamiView protein in Pfam
PF03155 Alg6_Alg8, 1 hit

Sequencei

Sequence statusi: Complete.

Q497D1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAFGLAAGS GHWFSALALG VTLLKCLLIP TYHSTDFEVH RNWLAITHNL
60 70 80 90 100
PISQWYYEAT SEWTLDYPPF FAWFEYALSH IAKYFDQEML DIHNLNYYSS
110 120 130 140 150
RTLLFQRFSV ILTDALFVYA VHECCKCIDG KRTGKDPTEK PKFVLSVLLL
160 170 180 190 200
WNFGLLIVDH IHFQYNGLLS GLLLLSIARL FQKRHIEGAF LFAVLLHFKH
210 220 230 240 250
IYLYVAPAYG IYLLRSYCFT ASKPDGSVRW DSFSIVRVTA LALIVFLVSA
260 270 280 290 300
LSLGPFLALN QLPQVFSRLF PFKRGLCHAY WAPNFWALYS ALDKALCVTG
310 320 330 340 350
LELKLLDPSQ IPRASMTSGL VQQSQHTVLP SVSPSATLIC TLIAILPSVF
360 370 380 390 400
CLWFKPQGPR GFLRCLVLCA LSSFMFGWHV HEKAILLAIL PMSLLAVEKA
410 420 430 440 450
GDATIFLILT TTGHYSLFPL LFTAPELPIK ILLMSLFTVY SISSLRTLFR
460 470 480 490 500
KEKPLFNWME TLYLLGLGPL EVCCEFLFPF TSWKLKYPFI PLLLTSVYCA
510 520
VGITYAWIRL YASVLTGCLV SKTKKH
Length:526
Mass (Da):59,663
Last modified:September 13, 2005 - v1
Checksum:iBD9D0FBDDBCE35A7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC100614 mRNA Translation: AAI00615.1
RefSeqiNP_001029299.1, NM_001034127.1
UniGeneiRn.12688

Genome annotation databases

GeneIDi293129
KEGGirno:293129
UCSCiRGD:1305468 rat

Similar proteinsi

Entry informationi

Entry nameiQ497D1_RAT
AccessioniPrimary (citable) accession number: Q497D1
Entry historyiIntegrated into UniProtKB/TrEMBL: September 13, 2005
Last sequence update: September 13, 2005
Last modified: May 23, 2018
This is version 72 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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