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Protein
Submitted name:

NK-3 transcription factor, locus 1 (Drosophila)

Gene

Nkx3-1

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

DNA-bindingUniRule annotationSAAS annotationImported

Names & Taxonomyi

Protein namesi
Submitted name:
NK-3 transcription factor, locus 1 (Drosophila)Imported
Submitted name:
NK3 homeobox 1Imported
Submitted name:
Protein Nkx3-1Imported
Gene namesi
Name:Nkx3-1Imported
ORF Names:rCG_36969Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 15

Organism-specific databases

RGDi1305369. Nkx3-1.

Subcellular locationi

  • Nucleus UniRule annotationSAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

NucleusUniRule annotationSAAS annotation

Expressioni

Gene expression databases

BgeeiENSRNOG00000015477.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000020753.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini124 – 18461Homeobox DNA-bindingInterPro annotationAdd
BLAST

Sequence similaritiesi

Contains homeobox DNA-binding domain.SAAS annotation

Keywords - Domaini

HomeoboxUniRule annotationSAAS annotationImported

Phylogenomic databases

eggNOGiKOG0842. Eukaryota.
ENOG410XR21. LUCA.
GeneTreeiENSGT00840000129671.
HOGENOMiHOG000231923.
HOVERGENiHBG006689.
KOiK09348.
OMAiQTAKQPQ.
OrthoDBiEOG091G0RNV.
TreeFamiTF315720.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
InterProiIPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR020479. Homeobox_metazoa.
IPR009057. Homeodomain-like.
[Graphical view]
PfamiPF00046. Homeobox. 1 hit.
[Graphical view]
PRINTSiPR00024. HOMEOBOX.
SMARTiSM00389. HOX. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiPS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q497B7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLRVAEPQEA RLEAGGRSPW AAPPTQSKRL TSFLIQDILR DHAERRGGQP
60 70 80 90 100
STPQHQCQPD PKRDSASELD EAEGSSVTLE DPPGIRSSPT ETRAETESDA
110 120 130 140 150
HFETYLLDCE HTPVLSSAPQ VTKQPQKRSR AAFSHTQVIE LERKFSHQKY
160 170 180 190 200
LSAPERAHLA KNLKLTETQV KIWFQNRRYK TKRRQLSEDL GVLEKNSTLS
210 220 230
LPTLKDDSLS RASLVSVYAS YPYYPYLYCL GSWHPTFW
Length:238
Mass (Da):27,120
Last modified:September 13, 2005 - v1
Checksum:i26D6592E2AB20AB6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC141168 Genomic DNA. No translation available.
BC100628 mRNA. Translation: AAI00629.1.
CH473951 Genomic DNA. Translation: EDM02182.1.
RefSeqiNP_001029316.1. NM_001034144.1.
UniGeneiRn.43468.

Genome annotation databases

EnsembliENSRNOT00000020753; ENSRNOP00000020753; ENSRNOG00000015477.
GeneIDi305999.
KEGGirno:305999.
UCSCiRGD:1305369. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC141168 Genomic DNA. No translation available.
BC100628 mRNA. Translation: AAI00629.1.
CH473951 Genomic DNA. Translation: EDM02182.1.
RefSeqiNP_001029316.1. NM_001034144.1.
UniGeneiRn.43468.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000020753.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000020753; ENSRNOP00000020753; ENSRNOG00000015477.
GeneIDi305999.
KEGGirno:305999.
UCSCiRGD:1305369. rat.

Organism-specific databases

CTDi4824.
RGDi1305369. Nkx3-1.

Phylogenomic databases

eggNOGiKOG0842. Eukaryota.
ENOG410XR21. LUCA.
GeneTreeiENSGT00840000129671.
HOGENOMiHOG000231923.
HOVERGENiHBG006689.
KOiK09348.
OMAiQTAKQPQ.
OrthoDBiEOG091G0RNV.
TreeFamiTF315720.

Gene expression databases

BgeeiENSRNOG00000015477.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
InterProiIPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR020479. Homeobox_metazoa.
IPR009057. Homeodomain-like.
[Graphical view]
PfamiPF00046. Homeobox. 1 hit.
[Graphical view]
PRINTSiPR00024. HOMEOBOX.
SMARTiSM00389. HOX. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiPS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ497B7_RAT
AccessioniPrimary (citable) accession number: Q497B7
Entry historyi
Integrated into UniProtKB/TrEMBL: September 13, 2005
Last sequence update: September 13, 2005
Last modified: September 7, 2016
This is version 99 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.